Proteolytic formation and properties of a fragment of protein C containing the .gamma.-carboxyglutamic acid rich domain and the EGF-like region

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Polyacrylamide Gel Electrophoresis of Viral Proteins

1971 • 1,477 citations

Deficiency of protein C in congenital thrombotic disease.

1981 • 1,260 citations

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C.

1982 • 709 citations

A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization.

1976 • 634 citations

Preparation and properties of bovine factor VIII (antihemophilic factor)

1980 • 504 citations

The inhibition of blood coagulation by activated protein C through the selective inactivation of activated factor V

1979 • 480 citations

The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases.

1987 • 479 citations

The Regulation of Hemostasis: The Protein C System

1986 • 443 citations

Reversible blocking of amino groups with citraconic anhydride

1968 • 430 citations

Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region

1987 • 399 citations

Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme

1982 • 385 citations

Inactivation of human coagulation factor V by activated protein C.

1983 • 374 citations

The nucleotide sequence of the gene for human protein C.

1985 • 360 citations

Vitamin K-Dependent Formation of γ-Carboxyglutamic Acid

1977 • 357 citations

Characterization of protein S, a .gamma.-carboxyglutamic acid containing protein from bovine and human plasma

1979 • 259 citations

Proteolytic activation of protein C from bovine plasma

1976 • 211 citations

Proteolytic formation and properties of gamma-carboxyglutamic acid-domainless protein C.

1983 • 202 citations

Preparation and partial characterization of two forms of bovine thrombin

1975 • 183 citations

Evolution and organization of the human protein C gene.

1986 • 169 citations

Amino acid sequence of the light chain of bovine protein C.

1982 • 162 citations

The interaction of a Ca2+-dependent monoclonal antibody with the protein C activation peptide region. Evidence for obligatory Ca2+ binding to both antigen and antibody.

1988 • 156 citations

Complete amino acid sequence of the light chain of human blood coagulation factor X: evidence for identification of residue 63 as .beta.-hydroxyaspartic acid

1983 • 142 citations

beta-Hydroxyaspartic acid in vitamin K-dependent protein C.

1983 • 138 citations

Structural changes required for activation of protein C are induced by Ca2+ binding to a high affinity site that does not contain gamma-carboxyglutamic acid.

1983 • 127 citations

Activation of prothrombin with (taipan snake) venom

1973 • 107 citations

Derivatives of blood coagulation factor IX contain a high affinity Ca2+-binding site that lacks gamma-carboxyglutamic acid.

1984 • 101 citations

Beta-hydroxyaspartic acid in the first epidermal growth factor-like domain of protein C. Its role in Ca2+ binding and biological activity.

1988 • 98 citations

Calcium-binding properties of bovine factor X lacking the gamma-carboxyglutamic acid-containing region.

1984 • 96 citations

Interaction of calcium with bovine plasma protein C

1981 • 88 citations

Hydroxylation of aspartic acid in domains homologous to the epidermal growth factor precursor is catalyzed by a 2-oxoglutarate-dependent dioxygenase.

1989 • 86 citations

Protein S, a new vitamin K‐dependent protein from bovine plasma

1979 • 70 citations

Inhibitors of 2-Ketoglutarate-dependent Dioxygenases Block Aspartyl β-Hydroxylation of Recombinant Human Factor IX in Several Mammalian Expression Systems

1989 • 69 citations

β-Hydroxyaspartic acid: Synthesis and separation of its diastereoisomers

1960 • 48 citations

Phospholipid binding properties of bovine prothrombin peptide residues 1-45.

1988 • 42 citations

Protein C in bovine plasma after warfarin treatment. Purification, partial characterization, and beta-hydroxyaspartic acid content.

1985 • 28 citations

Characterization of monoclonal antibodies against human protein C specific for the calcium ion‐induced conformation or for the activation peptide region

1985 • 26 citations

The role of the Gla domain in the activation of bovine coagulation factor X by the snake venom protein XCP

1983 • 26 citations

The effect of divalent cations on the amidolytic activity of bovine plasma activated protein C and des-1-41-light chain activated protein C.

1987 • 8 citations

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