Evolution and organization of the human protein C gene.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Deficiency of protein C in congenital thrombotic disease.

1981 • 1,260 citations

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

1978 • 1,117 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

1981 • 831 citations

The bidirectional transfer of DNA and RNA to nitrocellulose or diazobenzyloxymethyl-paper

1980 • 760 citations

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C.

1982 • 709 citations

Evolution of Proteolytic Enzymes

1984 • 641 citations

A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization.

1976 • 634 citations

Human Plasma Protein C

1979 • 511 citations

Recurrent Venous Thromboembolism in Patients with a Partial Deficiency of Protein S

1984 • 507 citations

Anticoagulant properties of bovine plasma protein C following activation by thrombin

1977 • 495 citations

Homozygous Protein C Deficiency Manifested by Massive Venous Thrombosis in the Newborn

1984 • 444 citations

Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: amino acid sequence homology with epidermal growth factor.

1983 • 403 citations

The gene structure of human anti-haemophilic factor IX.

1984 • 361 citations

The nucleotide sequence of the gene for human protein C.

1985 • 360 citations

INHERITED PROTEIN C DEFICIENCY AND COUMARIN-RESPONSIVE CHRONIC RELAPSING PURPURA FULMINANS IN A NEWBORN INFANT

1983 • 346 citations

The structure of the human tissue-type plasminogen activator gene: correlation of intron and exon structures to functional and structural domains.

1984 • 303 citations

Protein C Deficiency in a Dutch Family with Thrombotic Disease

1982 • 287 citations

Splice Junctions: Association with Variation in Protein Structure

1983 • 261 citations

Common evolutionary origin of the fibrin‐binding structures of fibronectin and tissue‐type plasminogen activator

1983 • 239 citations

Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity.

1985 • 216 citations

Deficiency of protein C inhibitor in combined factor V/VIII deficiency disease.

1980 • 207 citations

Organization of the rat γ-fibrinogen gene: Alternative mRNA splice patterns produce the γA and γB (γ′) chains of fibrinogen

1982 • 201 citations

Characterization of a cDNA coding for human protein C.

1984 • 183 citations

Amino acid sequence of the light chain of bovine protein C.

1982 • 162 citations

The structure and evolution of a 461 amino acid human protein C precursor and its messenger RNA, based upon the DNA sequence of cloned human liver cDNAs

1985 • 146 citations

Structure and Function of Protein C

1984 • 112 citations

THE PRIMARY STRUCTURE OF HUMAN UROGASTRONE

1977 • 99 citations

Proteolysis and Physiological Regulation

1976 • 89 citations

Amino acid sequence of crayfish (Astacus fluviatilis) trypsin If

1983 • 70 citations

Proteolysis and physiological regulation

1987 • 63 citations