Derivatives of blood coagulation factor IX contain a high affinity Ca2+-binding site that lacks gamma-carboxyglutamic acid.

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Fluorescence Energy Transfer as a Spectroscopic Ruler

1978 • 2,370 citations

Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

1981 • 831 citations

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C.

1982 • 709 citations

A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization.

1976 • 634 citations

Blood Coagulation

1980 • 562 citations

[2] Titration of trypsin, plasmin, and thrombin with p-nitrophenyl p′-guanidinobenzoate HCl

1970 • 497 citations

Anticoagulant properties of bovine plasma protein C following activation by thrombin

1977 • 495 citations

The inhibition of blood coagulation by activated protein C through the selective inactivation of activated factor V

1979 • 480 citations

Factor X activating enzyme from Russell's viper venom: isolation and characterization

1976 • 387 citations

Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme

1982 • 385 citations

Vitamin K Metabolism and Vitamin K Dependent Proteins

1980 • 375 citations

Basic Mechanisms in Blood Coagulation

1975 • 366 citations

Lanthanides as probes for calcium in biological systems

1979 • 362 citations

Vitamin K-Dependent Formation of γ-Carboxyglutamic Acid

1977 • 357 citations

Activation of bovine factor IX (Christmas factor) by factor XIa (activated plasma thromboplastin antecedent) and a protease from Russell's viper venom.

1978 • 332 citations

Functional properties of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

1981 • 330 citations

Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme

1982 • 308 citations

Molecular cloning of the gene for human anti-haemophilic factor IX

1982 • 272 citations

Proteolytic activation of protein C from bovine plasma

1976 • 211 citations

Isolation and characterization of bovine factor IX (Christmas factor)

1973 • 210 citations

Proteolytic formation and properties of gamma-carboxyglutamic acid-domainless protein C.

1983 • 202 citations

Mechanism of activation of bovine factor IX (Christmas factor) by bovine factor XIa(activated plasma thromboplastin antecedent)

1974 • 197 citations

Beta-hydroxyaspartic acid in vitamin K-dependent proteins.

1983 • 163 citations

Amino acid sequence of the light chain of bovine protein C.

1982 • 162 citations

Comparison of amino acid sequence of bovine coagulation Factor IX (Christmas Factor) with that of other vitamin K-dependent plasma proteins.

1979 • 147 citations

Complete amino acid sequence of the light chain of human blood coagulation factor X: evidence for identification of residue 63 as .beta.-hydroxyaspartic acid

1983 • 142 citations

beta-Hydroxyaspartic acid in vitamin K-dependent protein C.

1983 • 138 citations

A new vitamin K-dependent protein. A phospholipid-binding zymogen of a serine esterase.

1976 • 134 citations

Structural changes required for activation of protein C are induced by Ca2+ binding to a high affinity site that does not contain gamma-carboxyglutamic acid.

1983 • 127 citations

Calcium-binding properties of bovine factor X lacking the gamma-carboxyglutamic acid-containing region.

1984 • 96 citations

The occurrence of β-hydroxyaspartic acid in the vitamin K-dependent blood coagulation zymogens

1983 • 88 citations

Zymogens and Cofactors of Blood Coagulatio

1980 • 86 citations

Cooperative Ca2+ binding to human factor IX. Effects of Ca2+ on the kinetic parameters of the activation of factor IX by factor XIa.

1982 • 82 citations

Formation of a calcium-binding site on bovine activated factor V following recombination of the isolated subunits.

1982 • 75 citations

The interaction of Ca2+ with human factor IX

1981 • 49 citations

The binding of metal ions to bovine factor IX.

1978 • 43 citations

The binding of calcium to the activation products of bovine factor IX.

1979 • 35 citations

The role of the Gla domain in the activation of bovine coagulation factor X by the snake venom protein XCP

1983 • 26 citations

Metal ion specificity of the conversion of bovine factors IX, IX alpha, and IXa alpha to bovine factor IXa beta.

1980 • 20 citations