High promutagen activating capacity of yeast microsomes containing human cytochrome P-450 1A and human NADPH-cytochrome P-450 reductase

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture.

1982 • 1,559 citations

A general method for polyethylene-glycol-induced genetic transformation of bacteria and yeast

1983 • 462 citations

An improved bacterial test system for the detection and classification of mutagens and carcinogens

1973 • 295 citations

Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450.

1990 • 291 citations

Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae

1990 • 207 citations

Assay for gene mutation in a human lymphoblast line, AHH-1, competent for xenobiotic metabolism

1984 • 113 citations

Identification of a human liver cytochrome P-450 homologous to the major isosafrole-inducible cytochrome P-450 in the rat.

1986 • 110 citations

Mammalian cell mutagenicity and metabolism of heterocyclic aromatic amines

1991 • 90 citations

Primary Structure of Saccharomyces cerevisiae NADPH-Cytochrome P450 Reductase Deduced from Nucleotide Sequence of Its Cloned Gene1

1988 • 89 citations

Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.

1993 • 88 citations

The use of transgenic mice for short-term, in vivo mutagenicity testing

1990 • 85 citations

Cooked-food mutagens: current knowledge of formation and biological significance

1990 • 67 citations

Monoclonal Antibody-Directed Radioimmunoassay Detects Cytochrome P-450 in Human Placenta and Lymphocytes

1985 • 56 citations

Transfection of a human cytochrome P-450 gene into the human lymphoblastoid cell line, AHH-1, and use of the recombinant cell line in gene mutation assays

1989 • 52 citations

Constitutive and inducible expression of human cytochrome P450IA1 in yeast Saccharomyces cerevisiae: An alternative enzyme source for in vitro studies

1990 • 52 citations

Tests for recombinagens in somatic cells of Drosophila

1992 • 45 citations

Altered Regulation of the Cytochrome P4501A1 Gene: Novel Inducer-Independent Gene Expression in Pulmonary Carcinoma Cell Lines

1989 • 34 citations

Functional co-expression of human oxidoreductase and cytochrome P450 1A1 in Saccharomyces cerevisiae results in increased erod activity

1992 • 29 citations

Mitotic recombination in mammalian cells in vivo

1991 • 24 citations

Stable Expression of Mouse NADPH-Cytochrome P450 Reductase and Monkey P4501A1 cDNAs in Chinese Hamster Cells: Establishment of Cell Lines Highly Sensitive to Aflatoxin B1

1993 • 17 citations

Bacterial assays for recombinagens

1992 • 15 citations

The detection of promutagen activation by extracts of cells expressing cytochrome P450IA2 cDNA: preincubation dramatically increases revertant yield in the Ames test

1992 • 15 citations

A yeast strain for simultaneous detection of induced mitotic crossing over, mitotic gene conversion and reverse mutation

1975 • 13 citations