Release of Peptide Promoted by the GGQ Motif of Class 1 Release Factors Regulates the GTPase Activity of RF3

The Guanine Nucleotide-Binding Switch in Three Dimensions

2001 • 1,779 citations

A ratchet-like inter-subunit reorganization of the ribosome during translocation

2000 • 796 citations

The Crystal Structure of Human Eukaryotic Release Factor eRF1—Mechanism of Stop Codon Recognition and Peptidyl-tRNA Hydrolysis

2000 • 456 citations

Release factors differing in specificity for terminator codons.

1968 • 374 citations

Mutations in the highly conserved GGQ motif of class 1 polypeptide release factors abolish ability of human eRF1 to trigger peptidyl-tRNA hydrolysis

1999 • 352 citations

Large-Scale Movement of Elongation Factor G and Extensive Conformational Change of the Ribosome during Translocation

2000 • 293 citations

A tripeptide ‘anticodon’ deciphers stop codons in messenger RNA

2000 • 285 citations

Release factor RF3 in E.coli accelerates the dissociation of release factors RF1 and RF2 from the ribosome in a GTP-dependent manner

1997 • 281 citations

Novel Roles for Classical Factors at the Interface between Translation Termination and Initiation

1999 • 223 citations

A Posttermination Ribosomal Complex Is the Guanine Nucleotide Exchange Factor for Peptide Release Factor RF3

2001 • 206 citations

Translational termination comes of age

2000 • 202 citations

Bacterial Polypeptide Release Factor RF2 Is Structurally Distinct from Eukaryotic eRF1

2001 • 200 citations

The accuracy of codon recognition by polypeptide release factors

2000 • 161 citations

Class-1 translation termination factors: invariant GGQ minidomain is essential for release activity and ribosome binding but not for stop codon recognition

2001 • 151 citations

The hemK gene in Escherichia coli encodes the N5-glutamine methyltransferase that modifies peptide release factors

2002 • 150 citations

A post-translational modification in the GGQ motif of RF2 from Escherichia coli stimulates termination of translation

2000 • 142 citations

Identification of the prfC gene, which encodes peptide-chain-release factor 3 of Escherichia coli.

1994 • 134 citations

Localization and characterization of the gene encoding release factor RF3 in Escherichia coli.

1994 • 123 citations

Fast recycling of Escherichia coli ribosomes requires both ribosome recycling factor (RRF) and release factor RF3

1997 • 122 citations

Peptide chain termination

1980 • 120 citations

Hydrolysis of fMet-tRNA by Peptidyl Transferase

1971 • 103 citations

PEPTIDE CHAIN TERMINATION, III. STIMULATION OF in vitro TERMINATION

1969 • 98 citations