Peptide chain termination

The 3′-Terminal Sequence of Escherichia coli 16S Ribosomal RNA: Complementarity to Nonsense Triplets and Ribosome Binding Sites

1974 • 3,603 citations

Codon—anticodon pairing: The wobble hypothesis

1966 • 1,961 citations

A two-dimensional fractionation procedure for radioactive nucleotides

1965 • 1,162 citations

Amber Suppression: a Nucleotide Change in the Anticodon of a Tyrosine Transfer RNA

1968 • 420 citations

Inhibitors of protein synthesis

1974 • 411 citations

Release factors differing in specificity for terminator codons.

1968 • 374 citations

Genetic Code: The ‘Nonsense’ Triplets for Chain Termination and their Suppression

1965 • 369 citations

Co-Linearity of the Gene with the Polypeptide Chain

1964 • 368 citations

Tryptophan transfer RNA as the UGA suppressor

1971 • 362 citations

Polypeptide cleavages in the formation of poliovirus proteins.

1968 • 353 citations

Haemoglobin Constant Spring—A Chain Termination Mutant ?

1971 • 305 citations

Ribosome structure determined by electron microscopy of Escherichia coli small subunits, large subunits and monomeric ribosomes

1976 • 296 citations

Nonsense codons and polarity in the tryptophan operon

1966 • 284 citations

8-AZAGUANINE RESISTANCE IN MAMMALIAN CELLS I. HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE

1972 • 273 citations

Nonsense mutants and polarity in the Lac operon of Escherichia coli

1965 • 262 citations

Evidence for large precursor proteins in poliovirus synthesis.

1968 • 253 citations

Sense and Nonsense in the Genetic Code

1968 • 224 citations

Classification of aminotransferase (C gene) mutants in the histidine operon

1966 • 224 citations

Suppression in vitro: Identification of a Serine-sRNA as a "Nonsense" Suppressor

1965 • 219 citations

A CHANGE FROM NONSENSE TO SENSE IN THE GENETIC CODE

1962 • 219 citations

Polypeptide chain termination in vitro: isolation of a release factor.

1967 • 196 citations

The RNA Code and Protein Synthesis

1966 • 190 citations

Base Composition of Nonsense Condons in E. coli: Evidence from Amino-Acid Substitutions at a Tryptophan Site in Alkaline Phosphatase

1965 • 171 citations

A Strong Suppressor Specific for UGA

1967 • 171 citations

Nucleotide Sequence from the Polypeptide Chain Termination Region of the Coat Protein Cistron in Bacteriophage R17 RNA

1970 • 171 citations

UGA: A Third Nonsense Triplet in the Genetic Code

1967 • 169 citations

Suppressor genes for nonsense mutations

1965 • 167 citations

Translation of the UGA triplet in vitro by tryptophan transfer RNA's

1971 • 162 citations

SUPPRESSION OF MUTATIONS IN THE ALKALINE PHOSPHATASE STRUCTURAL CISTRON OF E. COLI

1962 • 154 citations

Restoration of operon activity by suppressors

1963 • 152 citations

Sequential Translation of Trinucleotide Codons for the Initiation and Termination of Protein Synthesis

1968 • 148 citations

Ribosome-catalyzed ester formation

1970 • 146 citations

Ribosome-catalyzed peptidyl transfer: substrate specificity at the P-site.

1968 • 146 citations

Polarity and the Degradation of mRNA

1969 • 145 citations

Ribosome-catalysed peptidyl transfer: the polyphenylalanine system

1968 • 140 citations

Mutations Affecting the Structure of Hypoxanthine: Guanine Phosphoribosyltransferase in Cultured Chinese Hamster Cells

1973 • 139 citations

Mutational Alteration of the Maximal Level of Lac Operon Expression

1966 • 130 citations

Nonsense Mutations and tRNA Suppressors

1980 • 130 citations

GENETIC MAPPING OF NONSENSE SUPPRESSORS IN YEAST

1968 • 128 citations

Characterization of Three Proteins Involved in Polypeptide Chain Termination

1969 • 119 citations

Stepwise synthesis of a tripeptide.

1968 • 115 citations

Molecular mechanisms of antibiotic action on protein biosynthesis and membranes

1974 • 114 citations

Polarity in the histidine operon

1966 • 111 citations

Characterization of reticulocyte release factor.

1977 • 110 citations

Amino Acid Sequence of the f2 Coat Protein

1967 • 107 citations

Haemoglobin Icaria, a new chain-termination mutant which causes α thalassaemia

1974 • 104 citations

Ribosome Structure

1978 • 103 citations

Hydrolysis of fMet-tRNA by Peptidyl Transferase

1971 • 103 citations

A Protein Involved in the Peptidyltransferase Activity of Escherichia coli Ribosomes

1973 • 102 citations

PEPTIDE CHAIN TERMINATION, III. STIMULATION OF in vitro TERMINATION

1969 • 98 citations

Tryptophan tRNA of Escherichia coli

1970 • 97 citations

Role of 5S RNA in the Functions of 50S Ribosomal Subunits

1971 • 96 citations

Ribosomal proteins. XXV. Immunological studies on Escherichia coli ribosomal proteins

1971 • 95 citations

The Peptidyl Transferase Activity of Ribosomes

1969 • 94 citations

Relief of Polarity in E. coli by “suA”

1970 • 93 citations

Fate of the message-ribosome complex upon translation of termination signals

1969 • 92 citations

Ribosomal protein neighborhoods. I. S18 and S21 as well as S5 and S8 are neighbors.

1972 • 91 citations

Possible involvement of peptidyl transferase in the termination step of protein biosynthesis

1969 • 91 citations

Ribosomes Cannot Interact Simultaneously with Elongation Factors EF Tu and EF G

1972 • 88 citations

Suppressor genes for nonsense mutations

1966 • 87 citations

Mammalian Peptide Chain Termination, II. Codon Specificity and GTPase Activity of Release Factor

1971 • 86 citations

Demonstration of a guanosine triphosphate-dependent enzymatic binding of aminoacyl-ribonucleic acid to Escherichia coli ribosomes.

1967 • 86 citations

Inability of E. coli ribosomes to interact simultaneously with the bacterial elongation factors EF Tu and EF G

1972 • 85 citations

Restriction and modification enzymes and their recognition sequences

1980 • 84 citations

Inhibition by Elongation Factor EF G of Aminoacyl-tRNA Binding to Ribosomes

1972 • 84 citations

Elongation Factors EF Tu and EF G Interact at Related Sites on Ribosomes

1972 • 83 citations

Yeast suppressors of UAA and UAG nonsense codons work efficiently in vitro via tRNA

1976 • 81 citations

Peptide Chain Termination, Codon, Protein Factor, and Ribosomal Requirements

1969 • 81 citations

Identification of nonsense codons in yeast

1969 • 81 citations

Proteins occurring at, or near, the subunit interface of E. coli ribosomes

1973 • 80 citations

The role of guanosine 5'-triphosphate in the initiation of peptide synthesis. 3. Binding of formylmethionyl-tRNA to ribosomes.

1967 • 77 citations

Amino acid substitutions resulting from suppression of nonsense mutations

1969 • 77 citations

Streptomycin Resistance Mutation in Escherichia coli : Altered Ribosomal Protein

1968 • 76 citations

PEPTIDE CHAIN TERMINATION, V. THE ROLE OF RELEASE FACTORS IN MRNA TERMINATOR CODON RECOGNITION

1969 • 76 citations

Guanosine 5'-triphosphatase activity of initiation factor f2.

1968 • 75 citations

The Requirement for Ribosomal Proteins L7 and L12 in Peptide-Chain Termination

1974 • 74 citations

Dissociation of Ribosomes on Polypeptide Chain Termination and Origin of Single Ribosomes

1970 • 70 citations

Peptide Chain Termination with Mammalian Release Factor

1970 • 67 citations

Location of proteins S5, S13 and S14 on the surface of the 30S ribosomal subunit from Escherichia coli as determined by immune electron microscopy

1974 • 66 citations

RECESSIVE LETHALS: A NEW CLASS OF NONSENSE SUPPRESSORS IN Escherichia coli

1969 • 66 citations

Transesterification by Peptidyl Transferase

1970 • 64 citations

Peptide Chain Termination: Effect of Protein S on Ribosomal Binding of Release Factors

1970 • 62 citations

Polypeptide chain tennination using synthetic polynucleotides

1965 • 59 citations

Loss of Dispensable Endonuclease Activity in Relief of Polarity by suA

1971 • 59 citations

Inhibition of Transcription of the Tryptophan Operon in Escherichia coli by a Block in Initiation of Translation

1971 • 59 citations

Demonstration of UAG as a nonsense codon in bakers' yeast by amino-acid replacements in iso-1-cytochrome c

1972 • 55 citations

Base composition of nonsense codons in Escherichia coli

1967 • 53 citations

Peptide Chain Termination, VII. The Ribosomal and Release Factor Requirements for Peptide Release

1970 • 51 citations

Identification of an ochre-suppressing anticodon

1971 • 50 citations

The conversion of amber suppressors to ochre suppressors.

1968 • 49 citations

Release Factors mediating Termination of Complete Proteins

1970 • 49 citations

Inhibition of peptide chain termination by antibodies specific for ribosomal proteins

1975 • 49 citations

Sequences of RNA fragments from the bacteriophage f2 coat protein cistron which differ from their R17 counterparts

1971 • 48 citations

The protein neighborhood of ribosome‐bound elongation factor Tu

1976 • 47 citations

Structural and functional studies of ribonucleoprotein fragments isolated from Escherichia coli 50 S ribosomal subunits

1975 • 46 citations

The Intercistronic Divide: Translation of an Intercistronic Region in the Histidine Operon of Salmonella typhimurium

1970 • 46 citations

Polypeptide Chain Termination

1971 • 45 citations

Polypeptide Chain Termination in Cell-Free Extracts of E. coli

1966 • 44 citations

Studies on Polynucleotides

1968 • 43 citations

Influence of Guanine Nucleotides and Elongation Factors on Interaction of Release Factors with the Ribosome

1973 • 42 citations

Release Factor Translation of RNA Phage Terminator Codons

1970 • 42 citations

Studies on the mechanism of polypeptide chain termination in cell-free extracts of E. coli.

1966 • 42 citations

Conserved Terminal Sequence in 18S rRNA May Represent Terminator Anticodons

1973 • 41 citations

Release of Polypeptide Chain Initiation Factor IF-2 During Initiation Complex Formation

1972 • 40 citations

Amino acid replacements resulting from super-suppression of a nonsense mutant of yeast

1968 • 34 citations

Translation of the genetic message, IV. UAA as a chain termination codon.

1967 • 34 citations

Peptide Chain Termination, VI. Purification and Site of Action of S

1970 • 32 citations

A leucyl-transfer RNA specified by the amber suppressor gene Su6+

1970 • 31 citations

Amino acid substitutions resulting from suppression of nonsense mutations

1970 • 30 citations

Polypeptide chain termination in vitro: Competition for nonsense codons between a purified release factor and suppressor tRNA

1970 • 28 citations

Suppression of UGA codon by a tryptophan tRNA

1971 • 28 citations

Sex-associated Differential Fluorescence of Mudminnow Chromosomes and Spermatozoa

1973 • 28 citations

Recessive-lethal nonsense suppressors in Salmonella typhimurium

1971 • 27 citations

Template Activity of Modified Terminator Codons

1970 • 27 citations

The release of polypeptide chains from ribosomes in cell-free amino acid-incorporating systems by specific combinations of bases in synthetic polyribonucleotides.

1965 • 26 citations

Characteristics of the Genetic Code in vivo

1966 • 25 citations

Inhibition of phenylalanyl-tRNA binding and elongation factor Tu-dependent GTP hydrolysis by antibodies specific for several ribosomal proteins

1974 • 25 citations

Amino acid substitutions resulting from suppression of nonsense mutations

1967 • 24 citations

Coordinate Inhibition of Elongation Factor G Function and Ribosomal Subunit Association by Antibodies to Several Ribosomal Proteins

1974 • 24 citations

REVERSION OF THE am LOCUS IN NEUROSPORA: EVIDENCE FOR NONSENSE SUPPRESSION

1968 • 22 citations

Peptide analyses of a protein component, 50-8, of 50s ribosomal subunit from erythromycin resistant mutants of Escherichia coli and Escherichia freundii

1972 • 21 citations

Release factor binding to ribosome requires an intact 16 S rRNA 3' terminus.

1977 • 20 citations

The universal RNA genetic code

1970 • 18 citations

Oligonucleotide-Ribosome-AA-sRNA Interactions

1966 • 17 citations

Release factor regulating termination of complete protein in a eukaryotic organism

1973 • 15 citations

A simple assay for protein chain termination using natural peptidyl-tRNA

1971 • 15 citations

Requirement for the Escherichia coli ribosomal protein L11 in peptide chain termination

1978 • 15 citations

Studies on polynucleotides. LXXXIII Synthesis in vitro of the tripeptide valyl-seryl-lysine directed by poly r(G-U-A-A)

1968 • 13 citations

Studies on peptidyl transferase in free ribosomes derived from rat liver

1974 • 13 citations

Untranslated T7 Phage mRNA is stabilized in suA Host

1971 • 11 citations

Asymmetries in Compact Sources at 2,298 MHz

1972 • 7 citations

Synthesis of a Chemically Reactive Analog of the Nonsense Codon U-G-A. Its Reaction with Ribosomes of Escherichia coli

1975 • 5 citations

UGA nonsense suppression assayed by T4 DNA-dependent in vitro synthesis of lysozyme

1970 • 4 citations