The prime-boost strategy: exciting prospects for improved vaccination

DNA VACCINES

1997 • 977 citations

Regulation of Immunity to Parasites by T Cells and T Cell-Derived Cytokines

1992 • 843 citations

Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara

1998 • 663 citations

Immunology Taught by Viruses

1996 • 656 citations

T Cell Affinity Maturation by Selective Expansion during Infection

1999 • 420 citations

Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations

1999 • 384 citations

Enhanced T-Cell Immunogenicity and Protective Efficacy of a Human Immunodeficiency Virus Type 1 Vaccine Regimen Consisting of Consecutive Priming with DNA and Boosting with Recombinant Fowlpox Virus

1998 • 334 citations

Host Range and Cytopathogenicity of the Highly Attenuated MVA Strain of Vaccinia Virus: Propagation and Generation of Recombinant Viruses in a Nonhuman Mammalian Cell Line

1997 • 334 citations

Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination

1997 • 314 citations

Effective Induction of Simian Immunodeficiency Virus-Specific Cytotoxic T Lymphocytes in Macaques by Using a Multiepitope Gene and DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccination Regimen

1999 • 312 citations

An inverse relationship between T cell receptor affinity and antigen dose during CD4⁺T cell responsesin vivoandin vitro

1999 • 259 citations

The Relationship Between Humoral and Cell‐Mediated Immunity

1972 • 228 citations

A case for cytokines as effector molecules in the resolution of virus infection

1993 • 216 citations

T lymphocyte responses in HIV-1 infection: implications for vaccine development

1999 • 116 citations

Fowlpox Virus Host Range Restriction: Gene Expression, DNA Replication, and Morphogenesis in Nonpermissive Mammalian Cells

1993 • 113 citations

DNA vaccination against virus infection and enhancement of antiviral immunity following consecutive immunization with DNA and viral vectors

1997 • 71 citations

The prime-boost concept applied to HIV preventive vaccines.

1997 • 67 citations