Multicenter Study of a Commercial, Automated Polymerase Chain Reaction System for the Rapid Detection of Mycobacterium tuberculosis in Respiratory Specimens in Routine Clinical Practice

Isolation and direct complete nucleotide determination of entire genes. Characterization of a gene coding for 16S ribosomal RNA

1989 • 2,622 citations

Detection and identification of mycobacteria by amplification of rRNA

1990 • 523 citations

Characterization of a Mycobacterium tuberculosis insertion sequence, IS6110, and its application in diagnosis

1990 • 483 citations

Sensitivity and specificity of PCR for detection of Mycobacterium tuberculosis: a blind comparison study among seven laboratories

1994 • 436 citations

RAPID DIAGNOSIS OF TUBERCULOSIS BY AMPLIFICATION OF MYCOBACTERIAL DNA IN CLINICAL SAMPLES

1989 • 406 citations

Detection ofMycobacterium tuberculosisin Sputum Samples Using a Polymerase Chain Reaction

1991 • 364 citations

Detection and identification of mycobacteria by amplification of mycobacterial DNA

1989 • 313 citations

An Internal Control for Routine Diagnostic PCR: Design, Properties, and Effect on Clinical Performance

1998 • 259 citations

Detection and identification of Mycobacterium tuberculosis directly from sputum sediments by amplification of rRNA

1993 • 258 citations

Reliability of nucleic acid amplification for detection of Mycobacterium tuberculosis: an international collaborative quality control study among 30 laboratories

1996 • 180 citations

Diagnostic performance of amplified Mycobacterium tuberculosis direct test with cerebrospinal fluid, other nonrespiratory, and respiratory specimens

1996 • 175 citations

Rapid diagnosis of pulmonary tuberculosis by using Roche AMPLICOR Mycobacterium tuberculosis PCR test

1995 • 164 citations

The Role of Clinical Suspicion in Evaluating a New Diagnostic Test for Active Tuberculosis

2000 • 154 citations

COBAS AMPLICOR: fully automated RNA and DNA amplification and detection system for routine diagnostic PCR

1996 • 143 citations

Diagnosis of Tuberculosis

1979 • 126 citations

Direct detection of Mycobacterium tuberculosis complex in respiratory specimens by Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test and Roche Amplicor Mycobacterium Tuberculosis Test

1995 • 108 citations

Detection and identification of Mycobacterium tuberculosis directly from sputum sediments by Amplicor PCR

1995 • 105 citations

Clinical evaluation of the Roche AMPLICOR PCR Mycobacterium tuberculosis test for detection of M. tuberculosis in respiratory specimens

1996 • 99 citations

Diagnosis of tuberculosis by Amplicor Mycobacterium tuberculosis test: a multicenter study

1995 • 98 citations

Evaluation of automated COBAS AMPLICOR PCR system for detection of several infectious agents and its impact on laboratory management

1996 • 92 citations

Evaluation of Amplicor PCR for direct detection of Mycobacterium tuberculosis from sputum specimens

1995 • 88 citations

Sequence analysis and amplification by polymerase chain reaction of a cloned DNA fragment for identification of Mycobacterium tuberculosis

1990 • 85 citations

Diagnostic value of an amplification method (Gen-Probe) compared with that of culture for diagnosis of tuberculosis

1995 • 84 citations

Multiplex strand displacement amplification (SDA) and detection of DNA sequences fromMycobacterium tuberculosisand other mycobacteria

1994 • 78 citations

Evaluation of Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test and Roche PCR-microwell plate hybridization method (AMPLICOR MYCOBACTERIUM) for direct detection of mycobacteria

1996 • 76 citations

Comparison of Amplicor, in-house PCR, and conventional culture for detection of Mycobacterium tuberculosis in clinical samples

1995 • 76 citations

Evaluation of Roche Amplicor PCR assay for Mycobacterium tuberculosis

1996 • 73 citations

Comparative evaluation of two commercial amplification assays for direct detection of Mycobacterium tuberculosis complex in respiratory specimens

1997 • 68 citations

Quantitative culture of Mycobacterium tuberculosis from clinical sputum specimens and dilution endpoint of its detection by the Amplicor PCR assay

1995 • 55 citations

Detection of Mycobacterium tuberculosis Complex in Sputum Specimens by the Automated Roche Cobas Amplicor Mycobacterium Tuberculosis Test

1998 • 54 citations

Detection of Mycobacterium tuberculosis in respiratory specimens by strand displacement amplification of DNA

1996 • 38 citations

Evaluation of the COBAS AMPLICOR MTB system

1997 • 30 citations

Detection ofMycobacterium tuberculosis complex in clinical specimens by a commercial polymerase chain reaction kit

1995 • 27 citations

Multicenter International Work Flow Study of an Automated Polymerase Chain Reaction Instrument

1998 • 27 citations

Comparison of amplified Q beta replicase and PCR assays for detection of Mycobacterium tuberculosis

1995 • 26 citations

Prospective clinical evaluation of Amplicor Mycobacterium tuberculosis PCR test as a screening method in a low-prevalence population

1996 • 25 citations

Assessment of Use of the COBAS AMPLICOR System with BACTEC 12B Cultures for Rapid Detection of Frequently Identified Mycobacteria

1999 • 24 citations

Detection of Mycobacterium tuberculosis in BACTEC 12B broth cultures by the Roche Amplicor PCR assay

1997 • 20 citations

Comparison of the Roche AMPLICOR MYCOBACTERIUM assay and Digene SHARP Signal System with in-house PCR and culture for detection of Mycobacterium tuberculosis in respiratory specimens

1996 • 19 citations

Evaluation of the roche amplicor™ polymerase chain reaction system for detection of Mycobacterium tuberculosis complex in specimens

1996 • 12 citations

Clinical evaluation of a commercial ligase-based gene amplification method for detection ofMycobacterium tuberculosis

1998 • 10 citations

AMPLICOR™ MTB polymerase chain reaction test for identification of Mycobacterium tuberculosis in positive difco ESP II broth cultures

1997 • 10 citations

[Reliability of Amplicor Mycobacteria test for detection of Mycobacterium tuberculosis complex. M. avium and M. intracellulare: a cooperative study among 9 laboratories].

1997 • 3 citations