Post-translational Processing and Renal Expression of Mouse Indian Hedgehog

Sonic hedgehog mediates the polarizing activity of the ZPA

1993 • 2,313 citations

Signal sequences

1985 • 2,179 citations

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 • 2,146 citations

Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein

1996 • 1,952 citations

HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo

1995 • 1,380 citations

PTH/PTHrP Receptor in Early Development and Indian Hedgehog—Regulated Bone Growth

1996 • 1,303 citations

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

1993 • 1,086 citations

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

1995 • 886 citations

Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein

1994 • 842 citations

Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud

1994 • 801 citations

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

1994 • 624 citations

Patterning of mammalian somites by surface ectoderm and notochord: Evidence for sclerotome induction by a hedgehog homolog

1994 • 594 citations

Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog

1992 • 585 citations

Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system

1990 • 562 citations

Autoproteolysis in hedgehog protein biogenesis

1994 • 541 citations

Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut

1995 • 531 citations

Hedgehog Patterning Activity: Role of a Lipophilic Modification Mediated by the Carboxy-Terminal Autoprocessing Domain

1996 • 529 citations

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

1995 • 505 citations

Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants

1995 • 491 citations

Ectopic expression of Sonic hedgehog alters dorsal-ventral patterning of somites

1994 • 451 citations

The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye

1993 • 423 citations

The TGFβ homolog dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina

1993 • 414 citations

Long-range sclerotome induction by sonic hedgehog: Direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway

1995 • 341 citations

Proteolytic Processing Yields Two Secreted Forms of Sonic hedgehog

1995 • 309 citations

Drosophila hedgehog acts as a morphogen in cellular patterning

1994 • 215 citations

Cloning, Expression, and Chromosomal Location of SHH and IHH: Two Human Homologues of the Drosophila Segment Polarity Gene Hedgehog

1995 • 191 citations

Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo

1993 • 172 citations

Identification, molecular cloning, and characterization of dual leucine zipper bearing kinase. A novel serine/threonine protein kinase that defines a second subfamily of mixed lineage kinases.

1994 • 125 citations

SA Gene Expression in the Proximal Tubule of Normotensive and Hypertensive Rats

1996 • 22 citations