Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gpl60

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

Infection of HTLV-III/LAV in HTLV-I-Carrying Cells MT-2 and MT-4 and Application in a Plaque Assay

1985 • 860 citations

Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.

1992 • 628 citations

Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus

1988 • 608 citations

Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway

1991 • 590 citations

Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160.

1988 • 442 citations

Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo.

1990 • 378 citations

Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein.

1990 • 360 citations

Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site.

1990 • 296 citations

Structural homology between the human fur gene product and the subtilisin-like protease encoded by yeast KEX2

1990 • 202 citations

Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex.

1990 • 190 citations

Failure of a human immunodeficiency virus (HIV) immune globulin to protect chimpanzees against experimental challenge with HIV.

1988 • 162 citations

Retained in vitro infectivity and cytopathogenicity of HIV-1 despite truncation of the C-terminal tail of the env gene product

1992 • 156 citations

Mutational analysis of the human immunodeficiency virus type 1 env gene product proteolytic cleavage site

1990 • 131 citations

Analysis of HIV particle formation using transient expression of subviral constructs in mammalian cells

1992 • 130 citations

Human retroviruses and aids, 1992

1992 • 119 citations

Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport

1989 • 103 citations

Mutations within the human immunodeficiency virus type 1 gp160 envelope glycoprotein alter its intracellular transport and processing

1991 • 75 citations

Expression of the human immunodeficiency virus envelope glycoprotein is restricted to basolateral surfaces of polarized epithelial cells

1989 • 73 citations

Characterization of an HIV-1 point mutant blocked in envelope glycoprotein cleavage

1990 • 71 citations

Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones

1989 • 61 citations

Expression of biologically active HIV glycoproteins using a T7 RNA polymerase-based eucaryotic vector system

1992 • 10 citations