Analysis of HIV particle formation using transient expression of subviral constructs in mammalian cells

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

1984 • 3,566 citations

Complete nucleotide sequence of the AIDS virus, HTLV-III

1985 • 2,236 citations

Active human immunodeficiency virus protease is required for viral infectivity.

1988 • 1,309 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

1985 • 1,155 citations

Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

1988 • 936 citations

Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1.

1989 • 831 citations

Assembly and release of HIV-1 precursor Pr55gag virus-like particles from recombinant baculovirus-infected insect cells

1989 • 734 citations

Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release.

1991 • 644 citations

Myristoylation-dependent replication and assembly of human immunodeficiency virus 1.

1990 • 634 citations

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA.

1989 • 634 citations

Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins

1987 • 517 citations

VIRAL PROTEINASES

1988 • 448 citations

Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity

1989 • 373 citations

Identification of a sequence required for efficient packaging of human immunodeficiency virus type 1 RNA into virions

1989 • 372 citations

The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region

1989 • 359 citations

Standardized and simplified nomenclature for proteins common to all retroviruses

1988 • 336 citations

Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220

1987 • 329 citations

The gag gene products of human immunodeficiency virus type 1: alignment within the gag open reading frame, identification of posttranslational modifications, and evidence for alternative gag precursors

1988 • 310 citations

Human immunodeficiency virus-like particles produced by a vaccinia virus expression vector.

1989 • 223 citations

Human immunodeficiency virus proteinase dimer as component of the viral polyprotein prevents particle assembly and viral infectivity.

1991 • 190 citations

Human immunodeficiency virus type 1 Pr55gag and Pr160gag-pol expressed from a simian virus 40 late replacement vector are efficiently processed and assembled into viruslike particles

1990 • 184 citations

High frequency of aberrant expression of moloney murine leukemia virus in clonal infections

1978 • 176 citations

Properties of avian retrovirus particles defective in viral protease

1990 • 172 citations

Activity of purified biosynthetic proteinase of human immunodeficiency virus on natural substrates and synthetic peptides.

1989 • 166 citations

Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments.

1991 • 161 citations

Creation and expression of myristylated forms of Rous sarcoma virus gag protein in mammalian cells

1989 • 152 citations

Human immunodeficiency virus type 1 protease cleaves the intermediate filament proteins vimentin, desmin, and glial fibrillary acidic protein.

1990 • 145 citations

Human immunodeficiency virus-like, nonreplicating, gag-env particles assemble in a recombinant vaccinia virus expression system

1990 • 144 citations

Morphogenesis and morphology of HIV structure-function relations

1989 • 140 citations

Identification oftrans-dominant HIV-1 rev protein mutants by direct transfer of bacterially produced proteins into human cells

1990 • 128 citations

Active site mutagenesis of the AIDS virus protease and its alleviation by trans complementation.

1988 • 127 citations

Expression of the gag-pol fusion protein of Moloney murine leukemia virus without gag protein does not induce virion formation or proteolytic processing

1988 • 125 citations

Production of human immunodeficiency virus (HIV)-like particles from cells infected with recombinant vaccinia viruses carrying the gag gene of HIV

1990 • 125 citations

Processing of in vitro-synthesized gag precursor proteins of human immunodeficiency virus (HIV) type 1 by HIV proteinase generated in Escherichia coli

1988 • 110 citations

Synthesis of Avian RNA Tumor Virus Structural Proteins

1974 • 110 citations

Incorporation of chimeric gag protein into retroviral particles

1990 • 108 citations

Cooperative dimeric and tetrameric clam haemoglobins are novel assemblages of myoglobin folds

1985 • 93 citations

Construction of a fusion gene that confers resistance against hygromycin B to mammalian cells in culture

1985 • 86 citations

Incorporation of 12-methoxydodecanoate into the human immunodeficiency virus 1 gag polyprotein precursor inhibits its proteolytic processing and virus production in a chronically infected human lymphoid cell line.

1991 • 70 citations

Processing, assembly, and immunogenicity of human immunodeficiency virus core antigens expressed by recombinant vaccinia virus

1990 • 66 citations

Identification and analysis of antisense RNA target regions of the human immunodeficiency virus type 1

1991 • 61 citations

Specific inhibitor of human immunodeficiency virus proteinase prevents the cytotoxic effects of a single-chain proteinase dimer and restores particle formation

1992 • 56 citations

Analysis of non-infectious HIV particles produced in presence of HIV proteinase inhibitor

1991 • 48 citations

Expression inEscherichiacoli and Purification of Human Immunodeficiency Virus Type 1 Capsid Protein (p24)

1990 • 42 citations

Human retroviruses, cancer, and AIDS: Approaches to prevention and therapy

1989 • 41 citations

Identification and characterization of human immunodeficiency virus type 1 gag-pol fusion protein in transfected mammalian cells

1991 • 32 citations