Tissue hypoxia (3rd European Consensus Conference in Intensive Care Medicine Organized by the Soci�t� de R�animation de Langue Fran�aise Co-sponsored by the American Thoracic Society In conjunction with the European Society of Intensive Care Medicine)

Prospective Trial of Supranormal Values of Survivors as Therapeutic Goals in High-Risk Surgical Patients

1988 • 1,808 citations

A Trial of Goal-Oriented Hemodynamic Therapy in Critically Ill Patients

1995 • 1,526 citations

Multiple Organ Failure Pathophysiology and Potential Future Therapy

1992 • 1,398 citations

Defense Strategies Against Hypoxia and Hypothermia

1986 • 1,098 citations

Heat shock, stress proteins, chaperones, and proteotoxicity

1991 • 1,069 citations

A Randomized Clinical Trial of the Effect of Deliberate Perioperative Increase of Oxygen Delivery on Mortality in High-Risk Surgical Patients

1993 • 949 citations

Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients

1992 • 865 citations

Effect of Stored-Blood Transfusion on Oxygen Delivery in Patients With Sepsis

1993 • 807 citations

Blood Lactate Levels Are Superior to Oxygen-Derived Variables in Predicting Outcome in Human Septic Shock

1991 • 717 citations

Validation of near-infrared spectroscopy in humans

1994 • 661 citations

Goal-Directed Fluid Therapy Based on Stroke Volume Variations Improves Fluid Management and Gastrointestinal Perfusion in Patients Undergoing Major Orthopedic Surgery

2014 • 628 citations

Elevation of Cardiac Output and Oxygen Delivery Improves Outcome in Septic Shock

1992 • 555 citations

Reevaluation of the Role of Cellular Hypoxia and Bioenergetic Failure in Sepsis

1992 • 383 citations

Preoperative Optimization of Cardiovascular Hemodynamics Improves Outcome in Peripheral Vascular Surgery

1991 • 373 citations

Regional blood flow and oxygen transport in septic shock

1993 • 358 citations

Effect of maximizing oxygen delivery on morbidity and mortality rates in critically ill patients

1993 • 354 citations

Prospective, Randomized Trial of Survivor Values of Cardiac Index, Oxygen Delivery, and Oxygen Consumption as Resuscitation Endpoints in Severe Trauma

1995 • 353 citations

A Controlled Clinical Trial of Dichloroacetate for Treatment of Lactic Acidosis in Adults

1992 • 318 citations

Identification of the critical oxygen delivery for anaerobic metabolism in critically ill septic and nonseptic humans

1993 • 280 citations

Prospective Trial of Supranormal Values as Goals of Resuscitation in Severe Trauma

1992 • 270 citations

Gut and muscle tissue PO2 in endotoxemic dogs during shock and resuscitation

1994 • 233 citations

Effect of cooling on oxygen consumption in febrile critically ill patients.

1995 • 231 citations

Effect of sepsis on activity of pyruvate dehydrogenase complex in skeletal muscle and liver.

1989 • 169 citations

The oxygen delivery/consumption controversy. Approaches to management of the critically ill.

1994 • 166 citations

Regional and Systemic Oxygen Delivery/Uptake Relations and Lactate Flux in Hyperdynamic, Endotoxin-treated Dogs

1992 • 135 citations

Evaluation of the role of cellular hypoxia in sepsis by the hypoxic marker [18F]fluoromisonidazole

1991 • 104 citations

Mathematical coupling explains dependence of oxygen consumption on oxygen delivery in ARDS.

1994 • 89 citations

The oxygen delivery/consumption controversy : approaches to management of the critically III

1994 • 83 citations

Gastric Tonometry: A New Monitoring Modality in the Intensive Care Unit

1995 • 53 citations

Hypoxia-induced bacterial translocation in the puppy

1992 • 33 citations

Of men and mitochondria: coping with hypoxic dysoxia. The 1980 J. Burns Amberson Lecture.

1980 • 27 citations

The first European Consensus Conference in Intensive Care Medicine: Introductory remarks

1992 • 24 citations