The Bloom syndrome protein interacts and cooperates with p53 in regulation of transcription and cell growth control

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1990 • 2,129 citations

The Bloom's syndrome gene product is homologous to RecQ helicases

1995 • 1,371 citations

The p53 pathway

1999 • 1,322 citations

Differential induction of transcriptionally active p53 following UV or lonizing radiation: Defects in chromosome instability syndromes?

1993 • 799 citations

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

2001 • 581 citations

Bloom Syndrome

1993 • 529 citations

The candidate tumour suppressor p33ING1cooperates with p53 in cell growth control

1998 • 294 citations

Transgenic mice with p53-responsive lacZ: p53activity varies dramatically during normal development and determines radiation and drug sensitivity invivo

1997 • 270 citations

Clinical implications of p53 mutations

1999 • 230 citations

p53-Mediated apoptosis is attenuated in Werner syndrome cells

1999 • 175 citations

Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains.

1996 • 171 citations

A putative nucleic acid-binding domain in Bloom's and Werner's syndrome helicases

1997 • 149 citations

Functional Interaction of p53 and BLM DNA Helicase in Apoptosis

2001 • 149 citations

Li-Fraumeni Syndrome and the Role of the p53 Tumor Suppressor Gene in Cancer Susceptibility

1998 • 34 citations