The role of interferon‐gamma in the pathogenesis of experimental autoimmune disease of the peripheral nervous system

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.

1983 • 1,918 citations

The Heterogeneity of Mononuclear Phagocytes in Lymphoid Organs: Distinct Macrophage Subpopulations in Rat Recognized by Monoclonal Antibodies ED1, ED2 and ED3

1985 • 1,605 citations

The Basis for the Immunoregulatory Role of Macrophages and Other Accessory Cells

1987 • 1,040 citations

Treatment of multiple sclerosis with gamma interferon

1987 • 739 citations

Identification of Ia glycoproteins in rat thymus and purification from rat spleen

1979 • 682 citations

ALLERGIC NEURITIS: AN EXPERIMENTAL DISEASE OF RABBITS INDUCED BY THE INJECTION OF PERIPHERAL NERVOUS TISSUE AND ADJUVANTS

1955 • 570 citations

Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors.

1986 • 532 citations

Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity.

1982 • 481 citations

Lymphokines

1987 • 459 citations

Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma.

1988 • 432 citations

In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon.

1987 • 396 citations

Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma.

1985 • 356 citations

Functions of Rat T‐Lymphocyte Subsets Isolated by Means of Monoclonal Antibodies

1983 • 330 citations

A permanent rat T cell line that mediates experimental allergic neuritis in the Lewis rat in vivo.

1984 • 257 citations

Macrophage-activating factor produced by a T cell hybridoma: physiochemical and biosynthetic resemblance to gamma-interferon.

1983 • 236 citations

Inflammation: Basic Principles and Clinical Correlates

1988 • 228 citations

Mechanism of demyelination in experimental allergic neuritis. Electron microscopic studies.

1969 • 224 citations

The Purification and Characterization of Rat Gamma Interferon by Use of Two Monoclonal Antibodies

1986 • 204 citations

Antigen presentation in the peripheral nervous system: Schwann cells present endogenous myelin autoantigens to lymphocytes

1986 • 184 citations

Mechanisms of lymphocyte adhesion to human vascular endothelial cells in culture. T lymphocyte adhesion to endothelial cells through endothelial HLA-DR antigens induced by gamma interferon.

1986 • 180 citations

Lymphocyte recruitment in delayed-type hypersensitivity. The role of IFN-gamma.

1988 • 170 citations

Treatment with gamma-interferon triggers the onset of collagen arthritis in mice

1988 • 158 citations

THE ROLE OF MACROPHAGES AND EICOSANOIDS IN THE PATHOGENESIS OF EXPERIMENTAL ALLERGIC NEURITIS

1988 • 152 citations

Activation of terminal components of complement in patients with Guillain-Barré syndrome and other demyelinating neuropathies.

1987 • 148 citations

Regulation by interferons of the local inflammatory response to bacterial lipopolysaccharide.

1987 • 140 citations

IL-1 and IFN-gamma increase vascular permeability.

1988 • 131 citations

In vitro and in vivo activation of human mononuclear phagocytes by interferon-gamma. Studies with normal and AIDS monocytes.

1987 • 124 citations

Biological and antigenic similarities of murine interferon-gamma and macrophage-activating factor.

1984 • 121 citations

Adhesion of lymphocytes to cerebral microvascular cells: effects of interferon-gamma, tumour necrosis factor and interleukin-1.

1988 • 119 citations

Conduction failure and nerve conduction slowing in experimental allergic neuritis induced by P₂‐specific T‐cell lines

1986 • 98 citations

Anti‐interferon‐γ antibody protects mice against the generalized Shwartzman reaction

1987 • 95 citations

Suppression of murine collagen-induced arthritis with monoclonal anti-Ia antibodies and augmentation with IFN-gamma.

1988 • 92 citations

Suppression of experimental autoimmune neuritis by the oxygen radical scavengers superoxide dismutase and catalase

1988 • 91 citations

Guillain‐barré syndrome

1987 • 88 citations

Immune Mechanisms in Inflammatory Polyneuropathya

1988 • 87 citations

Regulation of monocyte/macrophage C2 production and HLA-DR expression by IL-4 (BSF-1) and IFN-gamma.

1989 • 81 citations

Transfer of experimental allergic neuritis with P2-reactive T-cell lines

1985 • 79 citations

Demyelination and axonal degeneration in Lewis rat experimental allergic neuritis depend on the myelin dosage.

1988 • 71 citations

Complement depletion suppresses Lewis rat experimental allergic neuritis

1987 • 67 citations

The role of myelin P₂ protein in the production of experimental allergic neuritis

1984 • 58 citations

The role of macrophages in experimental autoimmune neuritis induced by a P₂‐Specific T‐Cell line

1988 • 57 citations

Blood-nerve barrier studies in experimental allergic neuritis

1985 • 55 citations

Suppression of experimental allergic neuritis by cyclosporin-A

1983 • 55 citations

Gamma interferon, but notMycobacterium leprae, induces major histocompatibility class II antigens on cultured rat Schwann cells

1987 • 50 citations

Interferon gamma and lipopolysaccharide promote macrophage adherence to basement membrane glycoproteins.

1989 • 50 citations

Protection against experimental allergic neuritis with silica quartz dust

1982 • 47 citations

Medicine at the end of life

1987 • 5 citations

Lymphokine Research and the Biology of Immunologic Diseases

1987 • 3 citations