Treatment with gamma-interferon triggers the onset of collagen arthritis in mice

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

Mac‐1: a macrophage differentiation antigen identified by monoclonal antibody

1979 • 1,144 citations

EXACERBATIONS OF MULTIPLE SCLEROSIS IN PATIENTS TREATED WITH GAMMA INTERFERON

1987 • 1,062 citations

Immunisation against heterologous type II collagen induces arthritis in mice

1980 • 1,025 citations

Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates.

1981 • 705 citations

Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors.

1986 • 532 citations

Structural studies on cartilage collagen employing limited cleavage and solubilization with pepsin

1972 • 420 citations

Serum transfer of collagen-induced arthritis in mice.

1983 • 414 citations

Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules.

1983 • 312 citations

A rat anti-mouse T4 monoclonal antibody (H129.19) inhibits the proliferation of Ia-reactive T cell clones and delineates two phenotypically distinct (T4+, Lyt-2,3-, and T4-, Lyt-2,3+) subsets among anti-Ia cytolytic T cell clones.

1984 • 308 citations

Nature of the collagen synthesized by a transplanted chondrosarcoma

1975 • 248 citations

Functional identity between murine γ Interferon and macrophage activating factor

1983 • 206 citations

The Purification and Characterization of Rat Gamma Interferon by Use of Two Monoclonal Antibodies

1986 • 204 citations

Homologous type II collagen induces chronic and progressive arthritis in mice

1986 • 196 citations

T‐Cell Unresponsiveness in vivo and in vitro: Fine Specificity of Induction and Molecular Characterization of the Unresponsive State

1987 • 190 citations

Prostaglandin production by rheumatoid synovial cells: stimulation by a factor from human mononuclear Cells.

1977 • 188 citations

Effect of IFN-γ on the immune response in vivo and on gene expression in vitro

1984 • 149 citations

Demonstration of a soluble mediator that induces exudates rich in Ia-positive macrophages.

1980 • 148 citations

Interferon-gamma regulates an antigen specific for endothelial cells involved in lymphocyte traffic.

1986 • 145 citations

The relationship between immune interferon production and proliferation in antigen-specific, MHC-restricted T cell lines and clones.

1983 • 141 citations

Female sex hormones suppress development of collagen‐induced arthritis in mice

1986 • 138 citations

High antibody response to autologous type II collagen is restricted to H-2 q

1986 • 109 citations

Interferon-gamma inhibits the action of B cell stimulatory factor (BSF)-1 on resting B cells.

1986 • 107 citations

In vivo and in vitro activation of alveolar macrophages by recombinant interferon-gamma.

1987 • 97 citations

Early appearance of activated CD4+ T lymphocytes and class II antigen-expressing cells in joints of DBA/1 mice immunized with type II collagen.

1988 • 93 citations

A demineralization procedure for immunohistopathological use

1986 • 92 citations

Role of T lymphocytes in murine collagen induced arthritis

1986 • 62 citations

An arthritogenic lymphokine in the rat.

1985 • 60 citations

Induction of MHC-determined antigens in the lung by interferon-gamma.

1986 • 55 citations

Changes in cell surface antigen expression on human articular chondrocytes induced by gamma‐interferon

1987 • 47 citations

In vivo induction of Ia antigens on rat keratinocytes by γ-interferon

1986 • 44 citations

Immune‐interferon (IFN‐γ), Macrophage‐activating Factors (MAFs), and Colony‐stimulating Factors (CSFs) Secreted by T Cell Clones in Limiting Dilution Microcultures, Long‐term Cultures, and by T Cell Hybridomas

1983 • 43 citations

Origin of the autoreactive anti-type II collagen response. I. Frequency of specific and multispecific B cells in primed murine lymph nodes.

1987 • 38 citations

Enhancement of DTH reaction and inhibition of the expression of class II transplantation antigens by in vivo treatment with antibodies against gamma-interferon.

1988 • 37 citations

Collagens Act as Ligands to Stimulate Human Monocytes to Produce Mononuclear Cell Factor (MCF) and Prostaglandins (PGE2)

1982 • 35 citations

Modulation of suppressor T cell induction with gamma-interferon.

1985 • 24 citations

Effect of cimetidine on wound healing in rats

1986 • 11 citations