Brain dysfunction associated with an induction of nitric oxide synthase following an intracerebral injection of lipopolysaccharide in rats

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Developments of a water-maze procedure for studying spatial learning in the rat

1984 • 6,896 citations

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1988 • 2,572 citations

Glutamate, nitric oxide and cell-cell signalling in the nervous system

1991 • 2,406 citations

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

1991 • 2,173 citations

Neuronal NADPH diaphorase is a nitric oxide synthase.

1991 • 1,917 citations

Nitric oxide, a novel neuronal messenger

1992 • 1,864 citations

Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

1989 • 1,850 citations

Regulation of biosynthesis of nitric oxide.

1994 • 1,698 citations

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

1994 • 1,578 citations

Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase

1991 • 1,364 citations

Aminoguanidine Prevents Diabetes-Induced Arterial Wall Protein Cross-Linking

1986 • 1,154 citations

A Requirement for the Intercellular Messenger Nitric Oxide in Long-Term Potentiation

1991 • 1,136 citations

Gases as biological messengers: nitric oxide and carbon monoxide in the brain

1994 • 1,052 citations

Bright and dark sides of nitric oxide in ischemic brain injury

1997 • 1,043 citations

Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures

1993 • 1,024 citations

Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger.

1991 • 1,016 citations

Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death

1992 • 939 citations

Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum

1991 • 875 citations

Synthesis of nitric oxide in CNS glial cells

1993 • 627 citations

Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains

1994 • 570 citations

Induction of Nitric Oxide Synthase in Glial Cells

1992 • 501 citations

Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures.

1992 • 484 citations

Inducible Nitric Oxide Synthase Gene Expression in Brain following Cerebral Ischemia

1995 • 479 citations

Long-Term Potentiation Is Reduced in Mice That Are Doubly Mutant in Endothelial and Neuronal Nitric Oxide Synthase

1996 • 436 citations

A correlation between soluble brain nitric oxide synthase and NADPH-diaphorase activity is only seen after exposure of the tissue to fixative

1993 • 428 citations

Immunologic NO Synthase: Elevation in Severe AIDS Dementia and Induction by HIV-1 gp41

1996 • 422 citations

Aminoguanidine selectively inhibits inducible nitric oxide synthase

1993 • 412 citations

Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.

1994 • 389 citations

Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage

1995 • 378 citations

Altered synaptic plasticity and memory formation in nitric oxide synthase inhibitor-treated rats.

1993 • 340 citations

Inducible Nitric Oxide Synthase Gene Expression in Vascular Cells After Transient Focal Cerebral Ischemia

1996 • 331 citations

Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS

1994 • 301 citations

Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease.

1996 • 285 citations

Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures

1994 • 251 citations

Hepatic and extrahepatic pathobiology of bacterial lipopolysaccharides.

1993 • 240 citations

Aminoguanidine Ameliorates and <scp>l</scp> -Arginine Worsens Brain Damage From Intraluminal Middle Cerebral Artery Occlusion

1996 • 184 citations

Attenuated hippocampal damage after global cerebral ischemia in mice mutant in neuronal nitric oxide synthase

1996 • 165 citations

Role of nitric oxide in learning and memory and in monoamine metabolism in the rat brain

1995 • 161 citations

Simultaneous Measurement of Nitrite and Nitrate Levels as Indices of Nitric Oxide Release in the Cerebellum of Conscious Rats

1997 • 160 citations

Diethyldithiocarbamate inhibits induction of macrophage NO synthase

1993 • 132 citations

Predominant localization in glial cells of freel-arginine. Immunocytochemical evidence

1991 • 119 citations

The role of nitric oxide in dizocilpine-induced impairment of spontaneous alternation behavior in mice.

1996 • 114 citations

Role of nitric oxide and cyclic GMP in the dizocilpine-induced impairment of spontaneous alternation behavior in mice

1996 • 110 citations

Nitric Oxide Synthase Expression in Glial Cells: Suppression by Tyrosine Kinase Inhibitors

1994 • 105 citations

NADPH-diaphorase activity in activated astrocytes represents inducible nitric oxide synthase

1994 • 104 citations

Potential role of nitric oxide in the pathophysiology of experimental bacterial meningitis in rats

1995 • 87 citations

Reduction in the number of NADPH-diaphorase-positive cells in the cerebral cortex and striatum in aged rats

1996 • 69 citations

Highly sensitive assay for choline acetyltransferase activity by high-performance liquid chromatography with electrochemical detection

1985 • 67 citations

Two pathways of nitric oxide production through glutamate receptors in the rat cerebellum in vivo

1997 • 66 citations

In vivo induction of inducible nitric oxide synthase by microinjection with interferon-? and lipopolysaccharide in rat hippocampus

1996 • 46 citations

Modulation of inducible nitric oxide synthase expression in astroglial cells

1994 • 42 citations

Protein Kinase C Modulates Calcium Sensitivity of Nitric Oxide Synthase in Cerebellar Slices

1995 • 42 citations

Stimulation of Arginine Transport and Nitric Oxide Production by Lipopolysaccharide Is Mediated by Different Signaling Pathways in Astrocytes

1995 • 41 citations

Pharmacological characterization of nitric oxide production in a rat model of meningitis

1996 • 36 citations

Possible involvement of tyrosine kinase activation in lipopolysaccharide-induced expression of Ca2+-insensitive but calmodulin-coupling nitric oxide synthase in rat glial cells

1996 • 25 citations

Changes in extracellular nitrite and nitrate levels after inhibition of glial metabolism with fluorocitrate

1997 • 15 citations

Effects of the subacute administration of nefiracetam on abnormal behavior in aged rats

1996 • 13 citations

The Effect of Nonionic Detergents on the Activity and/or Stability of Rat Brain Nitric Oxide Synthase

1993 • 12 citations

Inhibition of polyamine oxidase in rats improves the sensitivity of urinary polyamines as markers for cell death.

1990 • 9 citations

NITRIC OXIDE PRODUCTION IN VIVO IN THE BRAIN FOLLOWING A DIRECT INTRAHIPPOCAMPAL INJECTION OF LIPOPOLYSACCHARIDE IN RATS

1997 • 1 citations