Up-regulation of RGS4 mRNA by opioid receptor agonists in PC12 cells expressing cloned μ- or κ-opioid receptors

Molecular and Cellular Basis of Addiction

1997 • 1,324 citations

Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications

1995 • 1,267 citations

Turning off the signal: desensitization of β‐adrenergic receptor function

1990 • 1,241 citations

Molecular mechanisms of drug addiction

2004 • 1,080 citations

THE ROLE OF RECEPTOR KINASES AND ARRESTINS IN G PROTEIN–COUPLED RECEPTOR REGULATION

1998 • 1,074 citations

Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

1997 • 770 citations

GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits

1996 • 729 citations

The Regulator of G Protein Signaling Family

2000 • 586 citations

EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins

1996 • 573 citations

RGS family members: GTPase-activating proteins for heterotrimeric G-protein α-subunits

1996 • 547 citations

RGS Proteins and Signaling by Heterotrimeric G Proteins

1997 • 522 citations

Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family

1996 • 470 citations

Regulators of G-Protein Signaling (RGS) Proteins: Region-Specific Expression of Nine Subtypes in Rat Brain

1997 • 437 citations

Molecular mechanisms of drug addiction [published erratum appears in J Neurosci 1992 Aug;12(8):following table of contents]

1992 • 392 citations

RGS4 and GAIP are GTPase-activating proteins for G _qα and block activation of phospholipase Cβ by γ-thio-GTP-G _qα

1997 • 355 citations

RGS10 is a selective activator of Gαi GTPase activity

1996 • 354 citations

Molecular biology of the opioid receptors: structures, functions and distributions

1995 • 345 citations

Adrenergic Receptors as Models for G Protein-Coupled Receptors

1992 • 340 citations

Dynamic Regulation of RGS2 Suggests a Novel Mechanism in G-Protein Signaling and Neuronal Plasticity

1998 • 296 citations

GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain.

1995 • 291 citations

Molecular pharmacology of the opioid receptors

1995 • 255 citations

Emerging roles for RGS proteins in cell signalling

1999 • 255 citations

Cloning and expression of a cDNA for the rat k‐opioid receptor

1993 • 234 citations

Chronic Opioid Treatment Induces Adenylyl Cyclase V Superactivation

1996 • 198 citations

Multiple Morphine and Enkephalin Receptors and the Relief of Pain

1988 • 194 citations

Carboxyl-terminal Splicing of the Rat μ Opioid Receptor Modulates Agonist-mediated Internalization and Receptor Resensitization

1998 • 190 citations

Attenuation of G _i - and G _q -mediated signaling by expression of RGS4 or GAIP in mammalian cells

1997 • 176 citations

Adenylylcyclase Supersensitization in μ-Opioid Receptor-transfected Chinese Hamster Ovary Cells Following Chronic Opioid Treatment

1995 • 162 citations

RGS4 Inhibits Gq-mediated Activation of Mitogen-activated Protein Kinase and Phosphoinositide Synthesis

1997 • 157 citations

Differential Opioid Agonist Regulation of the Mouse μ Opioid Receptor

1997 • 124 citations

Mechanism of RGS4, a GTPase-activating Protein for G Protein α Subunits

1998 • 122 citations

Regulators of G Protein Signaling: Rapid Changes in mRNA Abundance in Response to Amphetamine

1998 • 111 citations

Specific Regulation of RGS2 Messenger RNA by Angiotensin II in Cultured Vascular Smooth Muscle Cells

2000 • 97 citations

Molecular cloning and in situ hybridization histochemistry for rat μ-opioid receptor

1994 • 95 citations

RGS9 proteins facilitate acute tolerance to mu‐opioid effects

2001 • 91 citations

Regulation of RGS mRNAs by cAMP in PC12 Cells

1998 • 79 citations

Expression of GTPase-deficient Giα2 Results in Translocation of Cytoplasmic RGS4 to the Plasma Membrane

1998 • 78 citations

A Set of Human Putative Lymphocyte G₀/G₁Switch Genes Includes Genes Homologous to Rodent Cytokine and Zinc Finger Protein-Encoding Genes

1990 • 77 citations

Comparison of mRNA Expression of Two Regulators of G-Protein Signaling,RGS1/BL34/1R20andRGS2/G0S8, in Cultured Human Blood Mononuclear Cells

1997 • 67 citations

Desensitization of the δ‐Opioid Receptor Correlates with Its Phosphorylation in SK‐N‐BE Cells: Involvement of a G Protein‐Coupled Receptor Kinase

1998 • 59 citations

Effects of regulators of G protein-signaling proteins on the functional response of the mu-opioid receptor in a melanophore-based assay.

1999 • 54 citations

Nerve growth factor induces specific enkephalin binding sites in a nerve cell line.

1982 • 43 citations

Characterization of a delta opioid receptor in rat pheochromocytoma cells.

1995 • 26 citations

Chronic fentanyl treatments induce the up-regulation of μ opioid receptor mRNA in rat pheochromocytoma cells

2000 • 20 citations

PC12 Cells as a Model to Study the Effects of Opioids on Normal and Tumoral Adrenal Chromaffin Cells

1995 • 13 citations

Sensitization of the Adenylyl Cyclase System in Cloned k-Opioid Receptor-Transfected Cells Following Sustained Agonist Treatment. A Chimeric Study Using G Protein .ALPHA.i2/.ALPHA.q Subunits.

1999 • 8 citations

Sensitization of the Adenylyl Cyclase System in Cloned κ-Opioid Receptor-Transfected Cells Following Sustained Agonist Treatment: A Chimeric Study Using G Protein αi2/αq Subunits

1999 • 3 citations