Phosphoinositide regulation of clathrin-mediated endocytosis

Regulated portals of entry into the cell

2003 • 3,642 citations

YOLK PROTEIN UPTAKE IN THE OOCYTE OF THE MOSQUITO AEDES AEGYPTI. L

1964 • 1,298 citations

Curvature of clathrin-coated pits driven by epsin

2002 • 1,008 citations

Endocytosis by Random Initiation and Stabilization of Clathrin-Coated Pits

2004 • 863 citations

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

2005 • 852 citations

Essential Role of Phosphoinositide Metabolism in Synaptic Vesicle Recycling

1999 • 825 citations

Phosphatidylinositol 4-Phosphate 5-Kinase α Is a Downstream Effector of the Small G Protein ARF6 in Membrane Ruffle Formation

1999 • 800 citations

Simultaneous Binding of PtdIns(4,5)P ₂ and Clathrin by AP180 in the Nucleation of Clathrin Lattices on Membranes

2001 • 719 citations

Molecular Architecture and Functional Model of the Endocytic AP2 Complex

2002 • 601 citations

Protein sorting into multivesicular endosomes

2003 • 496 citations

Multiple Roles for Arf6: Sorting, Structuring, and Signaling at the Plasma Membrane

2003 • 469 citations

ADAPTORS FOR CLATHRIN COATS: Structure and Function

2004 • 458 citations

Type Iγ phosphatidylinositol phosphate kinase targets and regulates focal adhesions

2002 • 436 citations

Distinct monoubiquitin signals in receptor endocytosis

2003 • 436 citations

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1γ by the FERM domain of talin

2002 • 432 citations

Dynamin and its partners: a progress report

1998 • 403 citations

Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking

2004 • 371 citations

Sorting it out

2003 • 347 citations

Phosphoinositides in membrane traffic at the synapse

2001 • 334 citations

PI-loting membrane traffic

2004 • 334 citations

C<scp>ELL</scp>B<scp>IOLOGY OF THE</scp>P<scp>RESYNAPTIC</scp>T<scp>ERMINAL</scp>

2003 • 327 citations

Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: Insights from vesicle recycling in nerve terminals

2004 • 322 citations

Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor

2002 • 304 citations

Phosphoinositide–Ap-2 Interactions Required for Targeting to Plasma Membrane Clathrin-Coated Pits

1999 • 304 citations

Fission and Uncoating of Synaptic Clathrin-Coated Vesicles Are Perturbed by Disruption of Interactions with the SH3 Domain of Endophilin

2000 • 297 citations

Phosphatidylinositol-(4,5)-Bisphosphate Regulates Sorting Signal Recognition by the Clathrin-Associated Adaptor Complex AP2

2005 • 289 citations

Endophilin Is Required for Synaptic Vesicle Endocytosis by Localizing Synaptojanin

2003 • 285 citations

A Structural Explanation for the Binding of Multiple Ligands by the α-Adaptin Appendage Domain

1999 • 284 citations

ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Iγ

2003 • 278 citations

Phosphatidylinositol Phosphate Kinases Put PI4,5P 2 in Its Place

2003 • 250 citations

Plasmalemmal Phosphatidylinositol-4,5-Bisphosphate Level Regulates the Releasable Vesicle Pool Size in Chromaffin Cells

2005 • 228 citations

ARF6 regulates a plasma membrane pool of phosphatidylinositol(4,5)bisphosphate required for regulated exocytosis

2003 • 228 citations

PIP Kinase Iγ Is the Major PI(4,5)P2 Synthesizing Enzyme at the Synapse

2001 • 223 citations

Evolving nature of the AP2 α-appendage hub during clathrin-coated vesicle endocytosis

2004 • 193 citations

Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses

2004 • 181 citations

Delineation of the Oligomerization, AP-2 Binding, and Synprint Binding Region of the C2B Domain of Synaptotagmin

1998 • 180 citations

Endocytosis and the cytoskeleton

2002 • 179 citations

A phosphatidylinositol (4,5)-bisphosphate binding site within μ2-adaptin regulates clathrin-mediated endocytosis

2002 • 166 citations

BAR domains and membrane curvature: bringing your curves to the BAR.

2005 • 153 citations

Phosphatidylinositol phosphate 5-kinase Iβ recruits AP-2 to the plasma membrane and regulates rates of constitutive endocytosis

2003 • 141 citations

Dual interaction of synaptotagmin with micro2- and alpha-adaptin facilitates clathrin-coated pit nucleation

2000 • 132 citations

Retrograde regulation of synaptic vesicle endocytosis and recycling

2003 • 126 citations

The Small G-protein Arf6GTP Recruits the AP-2 Adaptor Complex to Membranes

2005 • 107 citations

Recognition of a Basic AP-2 Binding Motif within the C2B Domain of Synaptotagmin Is Dependent on Multimerization

2004 • 74 citations

The Adaptor Complex 2 Directly Interacts with the α1b-Adrenergic Receptor and Plays a Role in Receptor Endocytosis

2003 • 74 citations

Site-Specific Cross-Linking Reveals a Differential Direct Interaction of Class 1, 2, and 3 ADP-Ribosylation Factors with Adaptor Protein Complexes 1 and 3

2002 • 62 citations

A presynaptic role for the ADP ribosylation factor (ARF)-specific GDP/GTP exchange factor msec7-1

1999 • 61 citations

Single-molecule live-cell imaging of clathrin-based endocytosis.

2005 • 17 citations