Transcriptional activation of a ras-like gene (kir) by oncogenic tyrosine kinases.

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction

1992 • 5,105 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

Induction of Chronic Myelogenous Leukemia in Mice by the P210 ^bcr/abl Gene of the Philadelphia Chromosome

1990 • 2,207 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

FUNCTION AND REGULATION OF RAS

1993 • 1,161 citations

PRIMARY RESPONSE GENES INDUCED BY GROWTH FACTORS AND TUMOR PROMOTERS

1991 • 1,078 citations

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

1984 • 913 citations

The Molecular Genetics of Philadelphia Chromosome–Positive Leukemias

1988 • 867 citations

Inhibition of NIH 3T3 Cell Proliferation by a Mutant ras Protein with Preferential Affinity for GDP

1988 • 757 citations

Acute leukaemia in bcr/abl transgenic mice

1990 • 701 citations

The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

1990 • 684 citations

BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

1993 • 667 citations

The ras protein family: evolutionary tree and role of conserved amino acids

1991 • 573 citations

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

1990 • 535 citations

Guanosine Triphosphatase Activating Protein (GAP) Interacts with the p21 ras Effector Binding Domain

1988 • 533 citations

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product

1988 • 402 citations

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.

1991 • 392 citations

In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome.

1987 • 380 citations

bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

1990 • 371 citations

An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia chromosome-positive human leukemias.

1993 • 317 citations

Rad: a Member of the Ras Family Overexpressed in Muscle of Type II Diabetic Humans

1993 • 301 citations

Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.

1986 • 291 citations

Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins.

1991 • 286 citations

Mutational analysis of a ras catalytic domain.

1986 • 205 citations

Differential Complementation of Bcr-Abl Point Mutants with c-Myc

1994 • 194 citations

The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.

1989 • 180 citations

Gem: an Induced, Immediate Early Protein Belonging to the Ras Family

1994 • 172 citations

Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice.

1993 • 158 citations

the Viral and Cellular Forms of the Abelson (Dbl) Oncogene

1988 • 157 citations

An active v-abl protein tyrosine kinase blocks immunoglobulin light-chain gene rearrangement.

1994 • 134 citations

SH1 Domain Autophosphorylation of P210 BCR/ABL Is Required for Transformation but Not Growth Factor Independence

1993 • 116 citations

Bruton's Tyrosine Kinase is a Key Regulator in B‐Cell Development

1994 • 107 citations

BCR First Exon Sequences Specifically Activate the BCR/ABL Tyrosine Kinase Oncogene of Philadelphia ChromosomePositive Human Leukemias

1991 • 97 citations

The BCR-ABL Oncogene Transforms Rat-1 Cells and Cooperates with v-myc

1989 • 50 citations

Activation of Tyrosine Kinase and Microfilament-Binding Functions of c-abl by bcr Sequences in bcr/abl Fusion Proteins

1991 • 47 citations

Mutational Analysis of a ras Catalytic Domain

1986 • 36 citations

Effector Domain Mutations Dissociate p21^ras Effector Function and GTPase-Activating Protein Interaction

1993 • 27 citations