Animal models of anxiety and depression: how are females different?
Data up to Jan 2025
Total Citations Per Year
Abstract
References (147)
Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States
1994 • 12,456 citations
The descent of man and selection in relation to sex
1907 • 11,265 citations
Sexual Selection and the Descent of Man
2017 • 6,982 citations
Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study
1997 • 4,490 citations
Behavioural despair in rats: A new model sensitive to antidepressant treatments
1978 • 3,035 citations
Psychopharmacology: The Fourth Generation of Progress
1995 • 2,920 citations
The Evolution of Human Sexuality
1979 • 2,337 citations
Learned helplessness: Theory and evidence.
1976 • 2,255 citations
The Growth of Biological Thought: Diversity, Evolution, and Inheritance
1982 • 2,170 citations
Sex Differences in Cognitive Abilities
2000 • 1,967 citations
Sex differences in unipolar depression: Evidence and theory.
1987 • 1,869 citations
Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation
1997 • 1,773 citations
The Expression of the Emotions in Man and Animals
2013 • 1,293 citations
Social Phobia
1992 • 1,133 citations
Sexual differentiation of the brain
1981 • 911 citations
Competition for mates and predominant juvenile male dispersal in mammals
1982 • 855 citations
Organizational and activational effects of sex steroids on brain and behavior: A reanalysis
1985 • 811 citations
Social Support and the Outcome of Major Depression
1989 • 743 citations
Exploratory behavior models of anxiety in mice
1985 • 730 citations
Animal models of anxiety: an ethological perspective
1997 • 648 citations
Gonadal hormones and sex differences in nonreproductive behaviors in rodents: Organizational and activational influences
1979 • 639 citations
Sensation seeking: A comparative approach to a human trait
1984 • 631 citations
The Stress Process and the Social Distribution of Depression
1999 • 589 citations
Sex differences in animal tests of anxiety
1991 • 576 citations
Variations in sex-related cognitive abilities across the menstrual cycle
1990 • 563 citations
Psychopathology in Women and Men: Focus on Female Hormones
1997 • 530 citations
Sex differences in dendritic atrophy of CA3 pyramidal neurons in response to chronic restraint stress
1997 • 522 citations
Visible burrow system as a model of chronic social stress: Behavioral and neuroendocrine correlates
1995 • 472 citations
Animal models for the study of anti-anxiety agents: A review
1985 • 457 citations
Neural Gonadal Steroid Actions
1981 • 451 citations
Depression: The predisposing influence of stress
1982 • 431 citations
Estrogen control of central neurotransmission: Effect on mood, mental state, and memory
1996 • 426 citations
Effects of the estrous cycle and ovarian hormones on behavioral indices of anxiety in female rats
1996 • 414 citations
Life Events and Depressive Disorder Reviewed
1980 • 402 citations
Rodent sex differences in emotional and related behavior
1975 • 390 citations
Sex Differences in the Prevalence and Detection of Depressive and Anxiety Disorders in General Health Care Settings
1998 • 375 citations
Sex differences in depression: a role for preexisting anxiety
1995 • 358 citations
Sex Differences in Spatial Ability: An Evolutionary Hypothesis and Test
1986 • 349 citations
Mother rats interact differently with male amd female offspring.
1979 • 340 citations
The influence of age and sex on the prevalence of depressive conditions: report from the National Survey of Psychiatric Morbidity
1998 • 336 citations
Animal models as simulations of depression
1991 • 328 citations
Effects of chronic mild stress on performance in behavioural tests relevant to anxiety and depression
1994 • 323 citations
Ethology and psychopharmacology
1995 • 316 citations
Ethoexperimental Approaches to the Study of Behavior
1989 • 307 citations
Influence of social isolation, gender, strain, and prior novelty on plus-maze behaviour in mice
1993 • 302 citations
Female rats are more vulnerable than males in an animal model of depression: the possible role of serotonin
1986 • 298 citations
Effects of housing on male and female rats: Crowding stresses males but calms females
1995 • 264 citations
Gender differences in pharmacokinetics and pharmacodynamics of psychotropic medication
1992 • 257 citations
Defeat is a major stressor in males while social instability is stressful mainly in females: towards the development of a social stress model in female rats
1999 • 250 citations
The Biology of Aggression
1981 • 246 citations
Stress: From synapse to syndrome.
1993 • 245 citations
Self-esteem and depression
1990 • 244 citations
Sex differences in emotional behaviour in mammals including man: Endocrine bases
1971 • 240 citations
Gender differences in depression: implications for treatment.
1997 • 238 citations
Social stress in mice
2001 • 235 citations
The Differences between the Sexes
1994 • 235 citations
The free-exploratory paradigm
1993 • 234 citations
Gender differences in pharmacokinetics and pharmacodynamics.
1999 • 223 citations
Animal Models in Psychopharmacology
1991 • 216 citations
Life History AND BIOECONOMY OF THE House Mouse
1992 • 204 citations
Social defeat and subordination as models of social stress in laboratory rodents: A review
1998 • 202 citations
5-Ht1a Agonists, 5-Ht3 Antagonists and Benzodiazepines: Their Comparative Behavioural Pharmacology
1991 • 194 citations
Sex differences in anxiety behavior in rats: Role of gonadal hormones
1993 • 193 citations
Sex and Estrous Cycle Variations of Rat Striatal Dopamine Uptake Sites
1993 • 186 citations
Selection, evolution of behavior and animal models in behavioral neuroscience
1999 • 184 citations
Sex differences in “cognitive” regions of the rat brain
1991 • 183 citations
Synaptogenic action of sex steroids in developing and adult neuroendocrine brain
1991 • 179 citations
Anxiety and depression: a common neurobiological substrate?
1988 • 174 citations
A regional study of sex differences in rat brain serotonin
1988 • 173 citations
Proximate and evolutionary studies of anxiety, stress and depression: synergy at the interface
1999 • 171 citations
Gender differences in the prevalence of depression: a survey in primary care
1999 • 170 citations
Psychosocial stress in tree shrews: Clomipramine counteracts behavioral and endocrine changes
1996 • 168 citations
Self-esteem and depression
1990 • 168 citations
Sex differences in psychiatric disorders: origins and developmental influences.
1987 • 167 citations
“Isolation stress” revisited: Isolation-rearing effects depend on animal care methods
1991 • 164 citations
Risk Assessment and Animal Models of Anxiety
1991 • 164 citations
RELATIONSHIPS BETWEEN EXPLORATORY BEHAVIOUR AND FEAR: A REVIEW
1973 • 163 citations
Diazepam changes risk assessment in an anxiety/defense test battery
1990 • 161 citations
Psychosocial Disorders in Young People
1995 • 159 citations
Behavioral correlates of chronic dominance-subordination relationships of male rats in a seminatural situation
1990 • 158 citations
Animal models of depression: Parallels and correlates to severe depression in humans
1985 • 155 citations
The interpretation of physiological correlates of differential housing in laboratory rats
1979 • 155 citations
Gender Differences in the Clinical Features of Unipolar Major Depressive Disorder
1990 • 153 citations
Gender differences in the presentation and management of social anxiety disorder.
1999 • 149 citations
Gender differences in depression in primary care
1995 • 148 citations
Sex effects in defensive behavior: Baseline differences and drug interactions
1991 • 148 citations
Genetically Triggered Sexual Differentiation of Brain and Behavior
1996 • 146 citations
Animal Models for Predicting Clinical Efficacy of Anxiolytic Drugs: Social Behaviour
1985 • 142 citations
Behaviorally Selective Effects of Neuroactive Steroids on Plus-Maze Anxiety in Mice
1998 • 140 citations
The actions of diazepam and serotonergic anxiolytics vary according to the gender and the estrous cycle phase
1990 • 136 citations
Effect of isolation on brain monoamines and the behavior of mice in tests of exploration, locomotion, anxiety and behavioral ‘despair’
1989 • 133 citations
Sex differences in behavioral despair: Relationships between behavioral despair and open field activity
1991 • 133 citations
Ethopharmacology of imipramine in the forced-swimming test: gender differences
1998 • 131 citations
Gender Differences in Brain and Behavior
1999 • 129 citations
Sex differences in forced-swim and open-field test behaviours after chronic administration of melatonin
2000 • 127 citations
Effects of isolation, handling and novelty on the pituitary-adrenal response in the mouse
1982 • 121 citations
Interindividual Variability in Swiss Male Mice: Relationship between Social Factors, Aggression, and Anxiety
1998 • 119 citations
Gender differences in human pharmacokinetics and pharmacodynamics
1994 • 119 citations
Progesterone and estrogens in rat brain: Modulation of GABA (γ-aminobutyric acid) receptor activity
1984 • 115 citations
Animal models of depression: an overview.
1984 • 111 citations
The epidemiology of depression
1968 • 109 citations
Low self‐esteem in different psychiatric conditions
1991 • 108 citations
Behavioral and physiological markers of experimental depression induced by social conflicts (DISC)
1998 • 102 citations
Social isolation in animal models of relevance to neuropsychiatric disorders
1996 • 97 citations
Gender differences in DSM-IV alcohol use disorders and major depression as distributed in the general population: Clinical implications
1997 • 97 citations
Effect of ovarian hormones on conflict behavior
1984 • 94 citations
Sex differences in GABA/benzodiazepine receptor changes and corticosterone release after acute stress in rats
1994 • 92 citations
Gender Differences in Depression and Antidepressant Pharmacokinetics and Adverse Events
2000 • 88 citations
Sex-dependent effects of aversive stimulation on holeboard and elevated plus-maze behavior
1991 • 87 citations
Natural History and Preventative Treatment of Recurrent Mood Disorders
1999 • 87 citations
Social stress by repeated defeat: effects on social behaviour and emotionality
1994 • 85 citations
Social stress of variable intensity: physiological and behavioral consequences
1999 • 82 citations
Gender bias in the preclinical psychopharmacology of anxiety: male models for (predominantly) female disorders
1995 • 80 citations
A model of ???antipredator??? defense in Swiss-Webster mice
1995 • 78 citations
The Organizational Concept and Vertebrates without Sex Chromosomes
1993 • 77 citations
Changes in tyrosine hydroxylase mRNA levels in medullary A1 and A2 neurons and locus coeruleus following castration and estrogen replacement in rats
1992 • 73 citations
A pretest procedure reliably predicts performance in two animal models of inescapable stress
1989 • 69 citations
Women and Anxiety
1989 • 67 citations
Loss of social status: preliminary evaluation of a novel animal model of depression
1995 • 64 citations
Sex differences in the course of depression: evidence from a longitudinal study of a representative sample of the Belgian population
1998 • 60 citations
Serotonergic interhemispheric asymmetry: gender difference in the orbital cortex
1991 • 54 citations
Puberal status and sex differences: Activity and maze behavior in rats
1976 • 53 citations
Influence of a natural stressor (predator odor) on locomotor activity in the meadow vole (Microtus pennsylvanicus): modulation by sex, reproductive condition and gonadal hormones
2000 • 52 citations
Investigation into sex-related differences in locomotor activity, place learning and passive avoidance responding in NMRI mice
1988 • 51 citations
Chronic Stress Effects on Sexual Behavior in Male and Female Rats
1998 • 51 citations
Effect of Induced Œstrus on Emotional Behaviour in Selected Strains of Rats
1964 • 47 citations
Anxiolytic actions of diazepam, but not of buspirone, are influenced by gender and the endocrine stage
1997 • 45 citations
Effects of gender and social isolation on electroencephalogram and neuroendocrine parameters in rats
1993 • 44 citations
Sex differences in open-field behavior in response to the β-carboline FG 7142 in rats
1993 • 42 citations
Short and Long Term Physiological and Neurochemical Adaptations to Social Conflict
1990 • 36 citations
Male urinary cues stimulate intra-sexual aggression and urine-marking in wild female mice, Mus musculus domesticus
1994 • 36 citations
Sex differences following pharmacological manipulation of the cholinergic system by DFP and philocarpine
1979 • 35 citations
A Comparison of Aggressiveness in Dominant Subordinate and Isolated House Mice
1981 • 34 citations
Development of open‐field behavior in mice: Effects of age and experience
1968 • 34 citations
Sex differences in the adrenergic response to hypoglycemic stress in human
1980 • 33 citations
Social stress in rats: An animal model of depression?
1995 • 31 citations
Gender differences in the development of depression
1996 • 30 citations
The influence of early and recent life stress on severity of depression
1990 • 24 citations
Gender differences in risk factors for mood and anxiety disorders: implications for clinical treatment research.
1995 • 23 citations
Malignant Primary Hypertension in Pregnancy Treated with Lisinopril
2000 • 21 citations
Brain structure: Causes and consequences of brain sex
1994 • 21 citations
Des variations intersexuelles relatives aux traitements en psychiatrie
1999 • 20 citations
Gender differences in reactivity of adult squirrel monkeys to short-term environmental challenges
1991 • 17 citations
Modulation of oxytocin secretion by ascending nordrenergic pathways: sexual dimorphism in rats
1987 • 15 citations
Maternal Sex-Stereotyping of Newborns
1994 • 13 citations
Behavioral and Social Sciences
1991 • 9 citations
An evaluation of the use of defeat-induced loss of status in the rat as a model of loss of self-esteem and depression in humans
1998 • 7 citations