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Self-Association Energetics of an Intact, Full-Length Nuclear Receptor: The B-Isoform of Human Progesterone Receptor Dimerizes in the Micromolar Range

Data up to Jan 2025

Published2005
Citations24
References62

Total Citations Per Year

Abstract

References (62)

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

Principles of Fluorescence Spectroscopy

1983 • 5,123 citations

How to measure and predict the molar absorption coefficient of a protein

1995 • 3,771 citations

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins*

1967 • 3,423 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

1998 • 2,622 citations

Proteins, amino acids and peptides

1943 • 2,189 citations

Analytical ultracentrifugation in biochemistry and polymer science

1995 • 1,970 citations

Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones*

1997 • 1,678 citations

Linked Functions and Reciprocal Effects in Hemoglobin: A Second Look

1964 • 1,613 citations

Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

1990 • 1,510 citations

Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter

2003 • 1,422 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques

1981 • 845 citations

Atomic structure of progesterone complexed with its receptor

1998 • 654 citations

Differential Gene Regulation by the Two Progesterone Receptor Isoforms in Human Breast Cancer Cells

2002 • 566 citations

Boundary analysis in sedimentation transport experiments: A procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile

1992 • 520 citations

MINIREVIEW: The Steroid Receptor Superfamily: More Excitement Predicted for the Future

1990 • 489 citations

λ Repressor and cro—components of an efficient molecular switch

1981 • 385 citations

Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor.

1990 • 333 citations

A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform.

1994 • 313 citations

Physical Biochemistry

1970 • 287 citations

Reproductive functions of the progesterone receptor isoforms: lessons from knock-out mice

2001 • 249 citations

Progesterone and Glucocorticoid Receptors Recruit Distinct Coactivator Complexes and Promote Distinct Patterns of Local Chromatin Modification

2003 • 244 citations

Rapid Periodic Binding and Displacement of the Glucocorticoid Receptor during Chromatin Remodeling

2004 • 234 citations

Breast Cancer Patients with Progesterone Receptor PR-A-Rich Tumors Have Poorer Disease-Free Survival Rates

2004 • 211 citations

PRINCIPLES OF FLUORESCENCE

1969 • 198 citations

Estrogen Receptor Dimerization: Ligand Binding Regulates Dimer Affinity and DimerDissociation Rate

2002 • 158 citations

Progesterone-Independent Effects of Human Progesterone Receptors (PRs) in Estrogen Receptor-Positive Breast Cancer: PR Isoform-Specific Gene Regulation and Tumor Biology

2004 • 140 citations

Dimerization of mammalian progesterone receptors occurs in the absence of DNA and is related to the release of the 90-kDa heat shock protein.

1991 • 133 citations

Homodimer formation is rate-limiting for high affinity DNA binding by glucocorticoid receptor.

1992 • 120 citations

Relative position of the hexahistidine tag effects binding properties of a tumor-associated single-chain Fv construct

2000 • 109 citations

Characterization and Functional Properties of the A and B Forms of Human Progesterone Receptors Synthesized in a Baculovirus System

1991 • 105 citations

Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin

2001 • 104 citations

Quantitative analysis of the glucocorticoid receptor-DNA interaction at the mouse mammary tumor virus glucocorticoid response element.

1990 • 101 citations

New Human Breast Cancer Cells to Study Progesterone Receptor Isoform Ratio Effects and Ligand-independent Gene Regulation

2002 • 95 citations

The N-terminal Region of the Human Progesterone A-receptor

2000 • 90 citations

Progesterone receptor and the mechanism of action of progesterone antagonists

1995 • 87 citations

Stoichiometric analysis of the specific interaction of the glucocorticoid receptor with DNA.

1986 • 79 citations

Hinge and Amino-Terminal Sequences Contribute to Solution Dimerization of Human Progesterone Receptor

1997 • 73 citations

Human factor VIIa and its complex with soluble tissue factor: evaluation of asymmetry and conformational dynamics by ultracentrifugation and fluorescence anisotropy decay methods

1993 • 73 citations

Functional properties of the N-terminal region of progesterone receptors and their mechanistic relationship to structure

2003 • 70 citations

The N-terminal Region of Human Progesterone B-receptors

2001 • 66 citations

Pure and functionally homogeneous recombinant retinoid X receptor.

1994 • 62 citations

Glucocorticosteroid Receptor Dimerization Investigated by Analysis of Receptor Binding to Glucocorticosteroid Responsive Elements Using a Monomer−Dimer Equilibrium Model

1996 • 61 citations

[14] Measurements of protein hydration by various techniques

1985 • 57 citations

Self-association Equilibria of Escherichia coli UvrD Helicase Studied by Analytical Ultracentrifugation

2003 • 53 citations

[17] Methods for extraction and quantification of receptors

1975 • 49 citations

Re-examining the oligomerization state of macrophage migration inhibitory factor (MIF) in solution

2004 • 47 citations

Dimerization of the Chicken Progesterone Receptorin VitroCan Occur in the Absence of Hormone and DNA

1990 • 44 citations

Characterization of the Calf Uterine Progesterone Receptor and Its Stabilization by Nucleic Acids*

1984 • 44 citations

[4] Linkage of protein assembly to protein-DNA binding

1995 • 44 citations

The Production of Antibodies Against the Conserved Cysteine Region of Steroid Receptors and Their Use in Characterizing the Avian Progesterone Receptor*

1988 • 43 citations

Characterization of R 5020 and RU 486 binding to progesterone receptor from calf uterus

1988 • 40 citations

Nuclear accessory factors enhance the binding of progesterone receptor to specific target DNA

1994 • 37 citations

NMR assignments for the amino-terminal residues of trp repressor and their role in DNA binding

1989 • 32 citations

Redox-Dependent DNA Binding of the Purified Androgen Receptor: Evidence for Disulfide-Linked Androgen Receptor Dimers

1999 • 30 citations

Differential DNA binding by calf uterine estrogen and progesterone receptors results from differences in oligomeric states

1991 • 30 citations

[5] Linkage at steady state: Allosteric transitions of thrombin

1995 • 15 citations

Specific binding of progesterone receptor to progesterone‐responsive elements does not require prior dimerization

1993 • 14 citations

Agonist and antagonist-induced qualitative and quantitative alterations of progesterone receptor from breast cancer cells.

1999 • 11 citations

Progesterone Receptor

2021 • 1 citations

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