Rapid activation of phosphatidate phosphohydrolase in mesangial cells by lipid A

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

Multiple, Distinct Forms of Bovine and Human Protein Kinase C Suggest Diversity in Cellular Signaling Pathways

1986 • 1,044 citations

Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins

1989 • 846 citations

Bacterial Endotoxins and Host Immune Responses

1980 • 629 citations

Growth factor-like action of phosphatidic acid

1986 • 531 citations

Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells.

1986 • 496 citations

Phosphatidate accumulation in hormone-treated hepatocytes via a phospholipase D mechanism.

1987 • 472 citations

Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin.

1980 • 441 citations

Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger.

1986 • 415 citations

Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism

1988 • 413 citations

ENZYMATIC ESTERIFICATION OF α-GLYCEROPHOSPHATE BY LONG CHAIN FATTY ACIDS

1953 • 412 citations

Stimulation of rat mesangial cell proliferation by macrophage interleukin 1.

1983 • 219 citations

Bacterial lipopolysaccharides prime macrophages for enhanced release of arachidonic acid metabolites.

1986 • 211 citations

Insulin Rapidly Increases Diacylglycerol by Activating De Novo Phosphatidic Acid Synthesis

1987 • 200 citations

Specific endotoxic lipopolysaccharide-binding proteins on murine splenocytes. I. Detection of lipopolysaccharide-binding sites on splenocytes and splenocyte subpopulations.

1988 • 173 citations

Interleukin 1 and the glomerular mesangium. I. Purification and characterization of a mesangial cell-derived autogrowth factor.

1986 • 164 citations

Regulation of protein kinase C activity by lipids

1988 • 155 citations

Oleic acid promotes the activation and translocation of phosphatidate phosphohydrolase from the cytosol to particulate fractions of isolated rat hepatocytes

1984 • 153 citations

Improved procedure for the separation of phospholipids by high-performance liquid chromatography

1982 • 152 citations

Neutral proteinase activity produced in vitro by cells of the glomerular mesangium

1983 • 149 citations

The de novo phospholipid effect of insulin is associated with increases in diacylglycerol, but not inositol phosphates or cytosolic Ca2+

1985 • 146 citations

Pertussis Toxin Inhibition of B Cell and Macrophage Responses to Bacterial Lipopolysaccharide

1986 • 140 citations

Interleukin-1 generates transmembrane signals from phospholipids through novel pathways in cultured rat mesangial cells.

1989 • 128 citations

Lipopolysaccharide and phorbol esters induce differentiation but have opposite effects on phosphatidylinositol turnover and Ca2+ mobilization in 70Z/3 pre-B lymphocytes.

1985 • 119 citations

Specific endotoxic lipopolysaccharide-binding proteins on murine splenocytes. II. Membrane localization and binding characteristics.

1988 • 111 citations

Bacterial lipopolysaccharides, phorbol myristate acetate, and zymosan induce the myristoylation of specific macrophage proteins.

1986 • 88 citations

Modulation of enzyme activities in isolated lymphocyte plasma membranes by enzymatic modification of phospholipid fatty acids.

1981 • 87 citations

Calcium-induced lateral phase separation in phosphatidic acid/phosphatidylcholine monolayers as revealed by fluorescence microscopy

1988 • 68 citations

Partial Purification, Properties, and Subcellular Distribution of Rat Liver Phosphatidate Phosphatase 1

1975 • 65 citations

Phospholipids containing polyunsaturated fatty acyl groups are mitogenic for normal mouse mammary epithelial cells in serum-free primary cell culture.

1989 • 62 citations

Interleukin I and the glomerular mesangium. II. Monokine stimulation of mesangial cell prostanoid secretion.

1987 • 60 citations

Effects of bacterial lipopolysaccharide on protein synthesis in murine peritoneal macrophages: Relationship to activation for macrophage tumoricidal function

1986 • 58 citations

Acylation of monocyte and glomerular mesangial cell proteins. Myristyl acylation of the interleukin 1 precursors.

1988 • 57 citations

Quantitative determination of phosphatidal ethanolamine and other phosphatides in various tissues of the rat

1968 • 51 citations

Effects of vasopressin and corticosterone on fatty acid metabolism and on the activities of glycerol phosphate acyltransferase and phosphatidate phosphohydrolase in rat hepatocytes

1984 • 50 citations

Signal Transmission in Exocrine Cells Is Associated with Rapid Activity Changes of Acyltransferases and Diacylglycerol Kinase Due to Reversible Protein Phosphorylation

1989 • 49 citations

Interleukin 1 and the glomerular mesangium. III. IL-1-dependent stimulation of mesangial cell protein kinase activity

1988 • 40 citations

Apparent phosphorylation — dephosphorylation of soluble phosphatidic acid phosphatase in rat liver

1982 • 36 citations

Angiogenin activates phospholipase C and elicits a rapid incorporation of fatty acid into cholesterol esters in vascular smooth muscle cells

1990 • 35 citations

Separation of 1-acylglycerolphosphate acyltransferase and 1-acylglycerolphosphorylcholine acyltransferase of rat liver microsomes.

1975 • 33 citations

Phosphatidic acid and arachidonic acid each interact synergistically with glucagon to stimulate Ca2+ influx in the perfused rat liver

1987 • 26 citations

Interleukin 1 release by human monocytes treated with liposome-encapsulated lipopolysaccharide.

1987 • 26 citations

Incorporation of cis-parinaric acid, a fluorescent fatty acid, into synaptosomal phospholipids by an acyl-CoA acyltransferase

1983 • 10 citations

Age-related changes in the translocation of phosphatidate phosphohydrolase from the cytosol to microsomal membranes in rat liver

1988 • 6 citations