Insulin Rapidly Increases Diacylglycerol by Activating De Novo Phosphatidic Acid Synthesis

Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger.

1986 • 415 citations

Insulin-Stimulated Hydrolysis of a Novel Glycolipid Generates Modulators of cAMP Phosphodiesterase

1986 • 383 citations

Insulin increases membrane and cytosolic protein kinase C activity in BC3H-1 myocytes.

1987 • 171 citations

Insulin-stimulated diacylglycerol production results from the hydrolysis of a novel phosphatidylinositol glycan.

1987 • 166 citations

How is phosphatidylcholine biosynthesis regulated?

1979 • 160 citations

The de novo phospholipid effect of insulin is associated with increases in diacylglycerol, but not inositol phosphates or cytosolic Ca2+

1985 • 146 citations

Effects of insulin and protein synthesis inhibitors on phospholipid metabolism, diacylglycerol levels, and pyruvate dehydrogenase activity in BC3H-1 cultured myocytes.

1984 • 136 citations

Phorbol Ester Provokes Insulin-Like Effects on Glucose Transport, Amino Acid Uptake, and Pyruvate Dehydrogenase Activity in BC3H-1 Cultured Myocytes*

1985 • 130 citations

The fatty acid composition of phosphatidylinositol from thrombin-stimulated human platelets.

1981 • 125 citations

Insulin acutely increases phospholipids in the phosphatidate-inositide cycle in rat adipose tissue.

1982 • 110 citations

The development of insulin receptors and responses in the differentiating nonfusing muscle cell line BC3H-1.

1984 • 105 citations

Measurement of flow of carbon atoms from glucose and glycogen glucose to glyceride glycerol and glycerol in rat heart and epididymal adipose tissue. Effects of insulin, adrenaline and alloxan-diabetes

1967 • 72 citations

Insulin-stimulated phosphoinositide metabolism in isolated fat cells.

1985 • 71 citations

Insulin activates phospholipase C in fat cells: similarity with the activation of pyruvate dehydrogenase

1984 • 66 citations

Equilibrium model for insulin-induced receptor down-regulation. Regulation of insulin receptors in differentiated BC3H-1 myocytes.

1984 • 64 citations

Insulin provokes a transient activation of phospholipase C in the rat epididymal fat pad.

1986 • 58 citations

The relationship between phosphatidylinositol metabolism and mobilization of intracellular calcium elicited by alpha1-adrenergic receptor stimulation in BC3H-1 muscle cells.

1984 • 40 citations

Effects of adrenocorticotropin and cycloheximide on adrenal diglyceride kinase

1981 • 29 citations

The Mechanism of Action of Insulin on Phospholipid Metabolism in Rat Adipose Tissue: Requirement for Protein Synthesis and a Carbohydrate Source, and Relationship to Activation of Pyruvate Dehydrogenase

1984 • 25 citations

Phosphatidylinositol hydrolysis and phosphatidylinositol 4′,5′-diphosphate hydrolysis are separable responses during secretagogue action in the rat pancreas

1985 • 20 citations

Further Evidence Implicating Diacylglycerol Generation and Protein Kinase C Activation in Agonist-Induced Increases in Glucose Uptake: Insulin-Like Effects of Phenylephrine in BC3H-1 Myocytes

1986 • 12 citations