Changes in Microsomal Phospholipases and Arachidonic Acid in Experimental Alcoholic Liver Injury: Relationship to Cytochrome P‐450 2E1 Induction and Conjugated Diene Formation

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Cytochrome P-450

1986 • 734 citations

Oxygen radical chemistry of polyunsaturated fatty acids

1989 • 716 citations

Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1)

1989 • 527 citations

[40] Spectrophotometric detection of lipid conjugated dienes

1984 • 485 citations

Biochemical and Molecular Basis of Alcohol-Induced Injury to Liver and Other Tissues

1988 • 452 citations

On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P-450. Products of oxygen reduction.

1984 • 324 citations

The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver

1989 • 320 citations

Ethanol-, fasting-, and aceton-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies

1988 • 316 citations

Ethanol-induced lipid peroxidation: potentiation by long-term alcohol feeding and attenuation by methionine.

1981 • 311 citations

Depressed hepatic glutathione and increased diene conjugates in alcoholic liver disease

1983 • 295 citations

Beef Fat Prevents Alcoholic Liver Disease in the Rat

1989 • 283 citations

Mammalian cytochromes P-450

1987 • 248 citations

Mechanisms of hydroxyl radical formation and ethanol oxidation by ethanol-inducible and other forms of rabbit liver microsomal cytochromes P-450.

1984 • 246 citations

Reactive free radical generation in vivo in heart and liver of ethanol-fed rats: correlation with radical formation in vitro.

1987 • 242 citations

Lipid peroxidation in human red cells.

1989 • 224 citations

Regulation of Microsomal Enzymes by Phospholipids

1971 • 207 citations

Role of xanthine oxidase in ethanol-induced lipid peroxidation in rats

1990 • 188 citations

Centrilobular expression of ethanol-inducible cytochrome P-450 (IIE1) in rat liver

1988 • 178 citations

Ethanol‐Induced Hepatic Fibrosis in the Rat: Role of the Amount of Dietary Fat

1986 • 158 citations

Ethanol and signal transduction in the liver.

1992 • 157 citations

Dietary linoleic acid is required for development of experimentally induced alcoholic liver injury

1989 • 143 citations

Ethanol and signal transduction in the liver

1992 • 138 citations

Monoclonal antibodies to ethanol-induced rat liver cytochrome P-450 that metabolizes aniline and nitrosamines.

1987 • 126 citations

The role of aldehyde oxidase in ethanol-induced hepatic lipid peroxidation in the rat

1990 • 111 citations

Decreased cytochrome oxidase activity in hepatic mitochondria after chronic ethanol consumption and the possible role of decreased cytochrome aa3 content and changes in phospholipids

1984 • 109 citations

Prognostic factors in patients with hepatocellular carcinoma receiving systemic chemotherapy

1992 • 107 citations

Female-Predominant Rat Hepatic P-450 Forms j (IIE1) and 3 (IIA1) Are under Hormonal Regulatory Controls Distinct from Those of the Sex-Specific P-450 Forms*

1989 • 97 citations

Dietary factors and Alcoholic Cirrhosis

1986 • 96 citations

Ethanol causes desensitization of receptor-mediated phospholipase C activation in isolated hepatocytes

1991 • 91 citations

Hydroxyl-radical production and ethanol oxidation by liver microsomes isolated from ethanol-treated rats

1986 • 88 citations

Role of acetone, dietary fat and total energy intake in induction of hepatic microsomal ethanol oxidizing system.

1988 • 79 citations

Ethanol Ingestion and Polyunsaturated Fatty Acids: Effects on the Acyl‐CoA Desaturases

1983 • 77 citations

The Formation of Monoacylglycerophosphate from sn-Glycerol 3-Phosphate by a Rat Liver Particulate Preparation

1970 • 73 citations

Effects of Dietary Fat Composition on Activities of the Microsomal Ethanol Oxidizing System and Ethanol‐Inducible Cytochrome P450 (CYP2E1) in the Liver of Rats Chronically Fed Ethanol

1992 • 71 citations

Effect of chronic ethanol administration on energy metabolism and phospholipase A2 activity in rat liver

1979 • 64 citations

[24] Rat hepatic P450IIA and P450IIC subfamily expression using catalytic, immunochemical, and molecular probes

1991 • 63 citations

New Perspectives in Catalase Dependent Ethanol Metabolism

1989 • 53 citations

Effects of Short‐Term Ethanol and Nutrition on the Hepatic Microsomal Monooxygenase System in a Model Utilizing Total Enteral Nutrition in the Rat

1991 • 49 citations

Hepatic lipid peroxidation and mitochondrial susceptibility to peroxidative attacks during ethanol inhalation and withdrawal

1983 • 48 citations

Reductive beta-scission of the hydroperoxides of fatty acids and xenobiotics: role of alcohol-inducible cytochrome P-450.

1990 • 47 citations

Drug Metabolizing Enzymes: Genetics, Regulation and Toxicology

1990 • 41 citations

The effect of ethanol on the fatty acid composition of hepatic microsomes and inner and outer mitochondrial membranes.

1971 • 31 citations

Degradation of arachidonyl phospholipids catalyzed by two phospholipases A2 and phospholipase C in a lipopolysaccharide-treated macrophage cell line, RAW264.7

1989 • 21 citations

The influence of CCl4 biotransformation on the activation of rat liver phospholipase C in vitro

1988 • 16 citations

Effects of Dietary Fat on Eicosanoid Production in Normal Tissues

1989 • 14 citations

Effect of phospholipid hydrolysis on the structural and functional integrity of mitochondria.

1971 • 8 citations