Sole BCR-ABL inhibition is insufficient to eliminate all myeloproliferative disorder cell populations

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A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

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A chemical switch for inhibitor-sensitive alleles of any protein kinase

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Principles of Tumor Suppression

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Versatile retroviral vectors for potential use in gene therapy.

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Design of allele-specific inhibitors to probe protein kinase signaling

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A novel pyridopyrimidine inhibitor of abl kinase is a picomolar inhibitor of Bcr-abl-driven K562 cells and is effective against STI571-resistant Bcr-abl mutants.

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Mutation of Threonine 766 in the Epidermal Growth Factor Receptor Reveals a Hotspot for Resistance Formation against Selective Tyrosine Kinase Inhibitors

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SH1 Domain Autophosphorylation of P210 BCR/ABL Is Required for Transformation but Not Growth Factor Independence

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Phosphoinositide 3-kinase signaling is essential for ABL oncogene–mediated transformation of B-lineage cells

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Protein Engineering of Protein Kinase A Catalytic Subunits Results in the Acquisition of Novel Inhibitor Sensitivity

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Src−Abl Tyrosine Kinase Chimeras: Replacement of the Adenine Binding Pocket of c-Abl with v-Src To Swap Nucleotide and Inhibitor Specificities

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Cutting Edge: A Chemical Genetic System for the Analysis of Kinases Regulating T Cell Development

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BCR–ABL alters the proliferation and differentiation response of multipotent hematopoietic cells to stem cell factor

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IL-3 receptor signaling is dispensable for BCR-ABL-induced myeloproliferative disease

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