Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells.

Cancer Cell Cycles

1996 • 5,379 citations

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

A minute chromosome in human chronic granulocytic leukemia

1960 • 2,329 citations

Induction of Chronic Myelogenous Leukemia in Mice by the P210 ^bcr/abl Gene of the Philadelphia Chromosome

1990 • 2,207 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1984 • 1,644 citations

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

1982 • 1,385 citations

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

1995 • 1,017 citations

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

1984 • 913 citations

Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis

1996 • 700 citations

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein.

1988 • 602 citations

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

1990 • 535 citations

Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia

1994 • 514 citations

The P190, P210, and P230 Forms of the BCR/ABL Oncogene Induce a Similar Chronic Myeloid Leukemia–like Syndrome in Mice but Have Different Lymphoid Leukemogenic Activity

1999 • 503 citations

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

1989 • 427 citations

Dominant negative MYC blocks transformation by ABL oncogenes

1992 • 410 citations

BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: a mechanism of resistance to multiple anticancer agents

1995 • 363 citations

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

1999 • 340 citations

Structural and Signaling Requirements for BCR-ABL-Mediated Transformation and Inhibition of Apoptosis

1995 • 282 citations

Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene

1995 • 261 citations

Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia

1999 • 243 citations

The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells

1997 • 228 citations

Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2.

1995 • 207 citations

Unregulated proliferation of primitive chronic myeloid leukemia progenitors in the presence of normal marrow adherent cells.

1986 • 191 citations

Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice.

1993 • 158 citations

Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells.

1989 • 145 citations

Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development

2000 • 140 citations

p19 ^Arf induces p53-dependent apoptosis during Abelson virus-mediated pre-B cell transformation

1998 • 137 citations

Secondary Mutation Maintains the Transformed State in BaF3 Cells With Inducible BCR/ABL Expression

1998 • 124 citations

Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL

1997 • 123 citations

Blast crisis in a murine model of chronic myelogenous leukemia.

1991 • 119 citations

Cooperative and redundant effects of STAT5 and Ras signaling in BCR/ABL transformed hematopoietic cells

2001 • 92 citations

Key Effectors of Signal Transduction and G 1 Progression

1998 • 53 citations

bcr/abl expression in 32D cl3(G) cells inhibits apoptosis induced by protein tyrosine kinase inhibitors.

1994 • 50 citations

BCR-ABL and v-SRC tyrosine kinase oncoproteins support normal erythroid development in erythropoietin receptor-deficient progenitor cells

1999 • 45 citations

Clonal lymphoid progenitor cell lines expressing the BCR/ABL oncogene retain full differentiative function.

1990 • 44 citations