Disrupting 5-HT2A Receptor/PDZ Protein Interactions Reduces Hyperalgesia and Enhances SSRI Efficacy in Neuropathic Pain

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

Ethical guidelines for investigations of experimental pain in conscious animals

1983 • 7,639 citations

Descending control of pain

2002 • 2,885 citations

Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors

2002 • 2,019 citations

Algorithm for neuropathic pain treatment: An evidence based proposal

2005 • 1,341 citations

Antidepressants for neuropathic pain

2007 • 761 citations

Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin

2005 • 749 citations

Streptozocin-induced diabetic rats: behavioural evidence for a model of chronic pain

1993 • 447 citations

PSD-95 is required for activity-driven synapse stabilization

2007 • 443 citations

Antidepressants and pain

2006 • 402 citations

Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex

2008 • 213 citations

Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2C receptor

1996 • 193 citations

Rapid modulation of spine morphology by the 5-HT _2A serotonin receptor through kalirin-7 signaling

2009 • 186 citations

The Serotonin 5-HT2A and 5-HT2C Receptors Interact with Specific Sets of PDZ Proteins

2004 • 167 citations

Impaired NMDA Receptor-Mediated Postsynaptic Function and Blunted NMDA Receptor-Dependent Persistent Pain in Mice Lacking Postsynaptic Density-93 Protein

2003 • 148 citations

Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice

2007 • 144 citations

Mice Lacking Central Serotonergic Neurons Show Enhanced Inflammatory Pain and an Impaired Analgesic Response to Antidepressant Drugs

2007 • 140 citations

An Investigation of Monoamine Receptors Involved in Antinociceptive Effects of Antidepressants

2002 • 137 citations

Neuropathic Sensitization of Behavioral Reflexes and Spinal NMDA Receptor/CaM Kinase II Interactions Are Disrupted in PSD-95 Mutant Mice

2003 • 122 citations

PSD-95 Is Essential for Hallucinogen and Atypical Antipsychotic Drug Actions at Serotonin Receptors

2009 • 118 citations

Disruption of nNOS‐PSD95 protein–protein interaction inhibits acute thermal hyperalgesia and chronic mechanical allodynia in rodents

2009 • 101 citations

Antiallodynic effect of intrathecally administered 5-HT2 agonists in rats with nerve ligation

2001 • 87 citations

PICK1 uncoupling from mGluR7a causes absence-like seizures

2008 • 86 citations

Knockdown of PSD-95/SAP90 delays the development of neuropathic pain in rats

2001 • 74 citations

Opposite Effects of PSD-95 and MPP3 PDZ Proteins on Serotonin 5-Hydroxytryptamine_2CReceptor Desensitization and Membrane Stability

2006 • 72 citations

Effect of intrathecal administration of serotonin in chronic pain models in rats

2000 • 70 citations

Expression of PSD-95/SAP90 is critical for N-methyl-d-aspartate receptor-mediated thermal hyperalgesia in the spinal cord

2000 • 68 citations

Effect of knock down of spinal cord PSD-93/chapsin-110 on persistent pain induced by complete Freund's adjuvant and peripheral nerve injury

2003 • 59 citations

Cell-permeable Peptide Tat-PSD-95 PDZ2 Inhibits Chronic Inflammatory Pain Behaviors in Mice

2008 • 59 citations

Antinociception with Intrathecal ??-Methyl-5-Hydroxytryptamine, a 5-Hydroxytryptamine2A/2C Receptor Agonist, in Two Rat Models of Sustained Pain

2003 • 53 citations

Fluvoxamine, a selective serotonin reuptake inhibitor, exerts its antiallodynic effects on neuropathic pain in mice via 5-HT2A/2C receptors

2006 • 51 citations

Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases

2008 • 50 citations

Role of postsynaptic density protein-95 in the maintenance of peripheral nerve injury-induced neuropathic pain in rats

2003 • 50 citations

Expression patterns of 5-HT receptor subtypes 1A and 2A on GABAergic neurons within the spinal dorsal horn of GAD67-GFP knock-in mice

2009 • 44 citations

Emerging strategies for the treatment of neuropathic pain

2006 • 43 citations

Serotonin potentiates the response of neurons of the superficial laminae of the rat spinal dorsal horn to γ-aminobutyric acid

2000 • 35 citations