Activation of cGMP phosphodiesterase in retinal rods: mechanism of interaction with the GTP-binding protein (transducin)

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment

1985 • 1,213 citations

Flow of information in the light-triggered cyclic nucleotide cascade of vision.

1981 • 740 citations

Characterization of transducin from bovine retinal rod outer segments. I. Separation and reconstitution of the subunits.

1983 • 492 citations

Isolation and characterization of cGMP phosphodiesterase from bovine rod outer segments.

1979 • 448 citations

Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments.

1980 • 391 citations

Purification and characterization of the gamma regulatory subunit of the cyclic GMP phosphodiesterase from retinal rod outer segments.

1982 • 336 citations

Kinetics of the Photocurrent of Retinal Rods

1972 • 334 citations

Characterization of transducin from bovine retinal rod outer segments. II. Evidence for distinct binding sites and conformational changes revealed by limited proteolysis with trypsin.

1983 • 331 citations

Characterization of bovine rod outer segment G-protein.

1982 • 281 citations

Purification and properties of the light-activated cyclic nucleotide phosphodiesterase of rod outer segments

1975 • 271 citations

cGMP phosphodiesterase of retinal rods is regulated by two inhibitory subunits.

1988 • 246 citations

Characterization of a bovine cone photoreceptor phosphodiesterase purified by cyclic GMP-sepharose chromatography.

1988 • 241 citations

Visual transduction in vertebrate rods and cones: A tale of two transmitters, calcium and cyclic GMP

1986 • 178 citations

Chapter 5 Interactions between photoexcited rhodopsin and light-activated enzymes in rods

1984 • 174 citations

Reciprocal control of retinal rod cyclic GMP phosphodiesterase by its γ subunit and transducin

1986 • 151 citations

Characterization of transducin from bovine retinal rod outer segments. Participation of the amino-terminal region of T alpha in subunit interaction.

1987 • 131 citations

[72] Real time assay of rod disk membrane cGMP phosphodiesterase and its controller enzymes

1982 • 125 citations

The G-protein of retinal rod outer segments (transducin). Mechanism of interaction with rhodopsin and nucleotides.

1985 • 122 citations

Activation mechanism of rod outer segment cyclic GMP phosphodiesterase. Release of inhibitor by the GTP/GTP-binding protein.

1983 • 117 citations

Activation of retinal rod cyclic GMP‐phosphodiesterase by transducin: Characterization of the complex formed by phosphodiesterase inhibitor and transducin α‐subunit

1986 • 102 citations

Kinetic studies suggest that light-activated cyclic GMP phosphodiesterase is a complex with G-protein subunits

1986 • 93 citations

Chemical cross-linking of bovine retinal transducin and cGMP phosphodiesterase.

1988 • 71 citations

Light‐Induced Interactions between Rhodopsin and the GTP‐Binding Protein

1982 • 70 citations

Interaction of retinal transducin with guanosine triphosphate analog: specificity of the .gamma.-phosphate binding region

1986 • 50 citations