Reciprocal control of retinal rod cyclic GMP phosphodiesterase by its γ subunit and transducin

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Cyclic GMP Cascade of Vision

1986 • 1,168 citations

Multiple cyclic nucleotide phosphodiesterase activities from rat brain

1971 • 1,054 citations

G Proteins: A Family of Signal Transducers

1986 • 975 citations

Flow of information in the light-triggered cyclic nucleotide cascade of vision.

1981 • 740 citations

Membrane formation in Tetrahymena pyriformis. 4. Lipid composition and biochemical properties of Tetrahymena pyriformis membrane systems

1971 • 674 citations

Isolation and characterization of cGMP phosphodiesterase from bovine rod outer segments.

1979 • 448 citations

Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments.

1980 • 391 citations

Light-activated phosphodiesterase of the rod outer segment. Kinetics and parameters of activation and deactivation.

1978 • 353 citations

Purification and characterization of the gamma regulatory subunit of the cyclic GMP phosphodiesterase from retinal rod outer segments.

1982 • 336 citations

Purification and properties of the light-activated cyclic nucleotide phosphodiesterase of rod outer segments

1975 • 271 citations

Trigger and Amplification Mechanisms in Visual Phototransduction

1985 • 196 citations

Magnitude of increase in retinal cGMP metabolic flux determined by 18O incorporation into nucleotide alpha-phosphoryls corresponds with intensity of photic stimulation.

1983 • 171 citations

Relationships within the family of GTP-binding proteins isolated from bovine central nervous system.

1985 • 160 citations

[72] Real time assay of rod disk membrane cGMP phosphodiesterase and its controller enzymes

1982 • 125 citations

Chapter 5 First Stage of Amplification in the Cyclic-Nucleotide Cascade of Vision

1981 • 121 citations

Activation mechanism of rod outer segment cyclic GMP phosphodiesterase. Release of inhibitor by the GTP/GTP-binding protein.

1983 • 117 citations

Stereochemistry of the guanyl nucleotide binding site of transducin probed by phosphorothioate analogs of GTP and GDP

1985 • 102 citations

Kinetic studies suggest that light-activated cyclic GMP phosphodiesterase is a complex with G-protein subunits

1986 • 93 citations

Characterization of transducin from bovine retinal rod outer segments. The role of sulfhydryl groups.

1984 • 78 citations

Guanine nucleotides and magnesium dependence of the association states of the subunits of transducin

1984 • 38 citations

Rod outer segment phosphodiesterase binding and activation in reconstituted membranes

1984 • 37 citations

Role of G-protein-receptor interaction in amplified phosphodiesterase activation of retinal rods.

1984 • 22 citations

Mechanism of cGMP control in retinal rod outer segments

1984 • 20 citations