Amplitude control of cell-cycle waves by nuclear import

Comprehensive Identification of Cell Cycle–regulated Genes of the YeastSaccharomyces cerevisiaeby Microarray Hybridization

1998 • 4,811 citations

A synthetic oscillatory network of transcriptional regulators

2000 • 4,543 citations

Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity

2000 • 911 citations

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

2001 • 761 citations

Kinetic analysis of translocation through nuclear pore complexes

2001 • 756 citations

Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2

2003 • 738 citations

Precision and functional specificity in mRNA decay

2002 • 713 citations

Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion

2001 • 706 citations

Serial Regulation of Transcriptional Regulators in the Yeast Cell Cycle

2001 • 664 citations

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

2001 • 575 citations

A Role for the Segment Polarity Gene shaggy/GSK-3 in the Drosophila Circadian Clock

2001 • 508 citations

The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SW15

1991 • 501 citations

Separase, Polo Kinase, the Kinetochore Protein Slk19, and Spo12 Function in a Network that Controls Cdc14 Localization during Early Anaphase

2002 • 441 citations

The degradation signal in a short-lived protein

1989 • 427 citations

The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation.

1992 • 414 citations

Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins

1993 • 376 citations

Regulation of Transcriptional Activation Domain Function by Ubiquitin

2001 • 363 citations

In vivo nuclear transport kinetics in Saccharomyces cerevisiae: a role for heat shock protein 70 during targeting and translocation.

1996 • 210 citations

Synthetic Gene Network for Entraining and Amplifying Cellular Oscillations

2002 • 210 citations

G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast.

1995 • 204 citations

Importin Provides a Link between Nuclear Protein Import and U snRNA Export

1996 • 189 citations

Securin and B-cyclin/CDK are the only essential targets of the APC

2003 • 178 citations

RNase MRP Cleaves the CLB2 mRNA To Promote Cell Cycle Progression: Novel Method of mRNA Degradation

2004 • 151 citations

Deregulated G₁-cyclin expression induces genomic instability by preventing efficient pre-RC formation

2002 • 150 citations

Cell Cycle Regulated Transport Controlled by Alterations in the Nuclear Pore Complex

2003 • 146 citations

Periodic Transcription: A Cycle within a Cycle

2003 • 141 citations

In Vivo Kinetics of mRNA Splicing and Transport in Mammalian Cells

2002 • 136 citations

Accelerating the Rate of Disassembly of Karyopherin·Cargo Complexes

2002 • 125 citations

Modeling the fission yeast cell cycle: Quantized cycle times in wee1 ⁻ cdc25Δ mutant cells

2000 • 120 citations

Recruitment of Thr 319-phosphorylated Ndd1p to the FHA domain of Fkh2p requires Clbkinase activity: a mechanism for CLB cluster gene activation

2003 • 111 citations

G₁ Cyclin Degradation: the PEST Motif of Yeast Cln2 Is Necessary, but Not Sufficient, for Rapid Protein Turnover

1994 • 108 citations

A genetic system for detection of protein nuclear import and export

2000 • 105 citations

Two Redundant Oscillatory Mechanisms in the Yeast Cell Cycle

2003 • 98 citations

Relationship between the function and the location of G1 cyclins inS. cerevisiae

2001 • 76 citations

Cyclin transcription: Timing is everything

2000 • 61 citations

Timing of Events in Mitosis

2002 • 57 citations

Mechanisms Controlling Subcellular Localization of the G₁ Cyclins Cln2p and Cln3p in Budding Yeast

2001 • 56 citations

Early Cell Cycle Box-Mediated Transcription ofCLN3 and SWI4 Contributes to the Proper Timing of the G₁-to-S Transition in Budding Yeast

2001 • 50 citations

Cell Cycle Activation of the Swi6p Transcription Factor Is Linked to Nucleocytoplasmic Shuttling

2003 • 48 citations

The strategy for coupling the RanGTP gradient to nuclear protein export

2003 • 42 citations