Ammonium chloride inhibits basal degradation of newly synthesized collagen in human fetal lung fibroblasts

Statistical methods

1967 • 19,533 citations

Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins

1971 • 1,396 citations

Proteinases in mammalian cells and tissues

1978 • 701 citations

Cathepsin B1. A lysosomal enzyme that degrades native collagen

1974 • 405 citations

Vesicles and cisternae in the trans golgi apparatus of human fibroblasts are acidic compartments

1985 • 350 citations

Fibroblasts degrade newly synthesised collagen within the cell before secretion

1978 • 201 citations

Control of collagen production by human diploid lung fibroblasts.

1980 • 158 citations

Intracellular degradation of newly synthesized secretory proteins

1983 • 158 citations

The ATP dependence of the degradation of short- and long-lived proteins in growing fibroblasts.

1985 • 113 citations

Bovine spleen cathepsin B1 and collagenolytic cathepsin. A comparative study of the properties of the two enzymes in the degradation of native collagen

1976 • 97 citations

Regulation of Collagen Production by the β-Adrenergic System

1981 • 83 citations

The purification of bovine cathepsin B1 and its mode of action on bovine collagens

1974 • 70 citations

Intracellular Degradation of Newly Synthesized Collagen

1984 • 67 citations

Measurement of intracellular collagen degradation

1981 • 46 citations

Effects of prostaglandin E1 on collagen production and degradation in human fetal lung fibroblasts

1988 • 38 citations

Lysosomal function in the degradation of defective collagen in cultured lung fibroblasts

1984 • 34 citations

Collagen degradation in human lung fibroblasts: Extent of degradation, role of lysosomal proteases, and evaluation of an alternate hypothesis

1984 • 32 citations

Lysosomotropic agents ammonium chloride and chloroquine inhibit both the synthesis and secretion of procollagen by freshly isolated embryonic chick tendon cells

1982 • 28 citations

Effects of puromycin and hydroxynorvaline on net production and intracellular degradation of collagen in human fetal lung fibroblasts

1989 • 23 citations

Rapid intracellular degradation of newly synthesized collagen by bone cells Effect of dichloromethylenebisphosphonate

1982 • 21 citations

The proteinase inhibitors leupeptin, pepstatin A, and TLCK cause reduced collagen production in freshly isolated embryonic chick fibroblasts in suspension culture

1984 • 11 citations

Radiochemical Purity of [14C]-Proline: Implications for Measurement of Intracellular Collagen Degradation

1984 • 7 citations

Collagen Degradation in Human Lung Fibroblasts Is Time Dependenta

1985 • 3 citations