Collagen degradation in human lung fibroblasts: Extent of degradation, role of lysosomal proteases, and evaluation of an alternate hypothesis

Fibroblasts degrade newly synthesised collagen within the cell before secretion

1978 • 201 citations

Regulation of the production of secretory proteins: Intracellular degradation of newly synthesized “defective” collagen

1980 • 164 citations

Intracellular degradation of newly synthesized secretory proteins

1983 • 158 citations

Type I osteogenesis imperfecta: a nonfunctional allele for pro alpha 1 (I) chains of type I procollagen.

1982 • 137 citations

Collagen biosynthesis by human skin fibroblasts. I. Optimization of the culture conditions for synthesis of type I and type III procollagens

1980 • 112 citations

Synthesis of a shortened pro-alpha 2(I) chain and decreased synthesis of pro-alpha 2(I) chains in a proband with osteogenesis imperfecta.

1983 • 107 citations

Minireview: Mechanisms of protein turnover in cultured cells

1981 • 104 citations

Ascorbate deficiency results in decreased collagen production: Under-hydroxylation of proline leads to increased intracellular degradation

1983 • 62 citations

Nonenzymatic hydroxylations of proline and lysine by reduced oxygen derivatives

1981 • 60 citations

Synthesis of collagen by human fibroblasts and their SV40 transformants

1980 • 59 citations

Simulation of Genetic Mucopolysaccharidoses in Normal Human Fibroblasts by Alteration of pH of the Medium

1972 • 54 citations

Measurement of intracellular collagen degradation

1981 • 46 citations

Intracellular degradation of newly synthesized collagen is conformation‐dependent

1981 • 40 citations

Intracellular Degradation of Newly Synthesized Collagen.

1982 • 36 citations

The appearance of free hydroxyproline as the major product of degradation of newly synthesized collagen in cell culture

1982 • 24 citations

Rapid intracellular degradation of newly synthesized collagen by bone cells Effect of dichloromethylenebisphosphonate

1982 • 21 citations

Reversible ultrastructural changes in human fibroblasts grown in hepes buffered MCDB-104 supplemented with human serum

1981 • 12 citations