Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (25)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1970 • 253,849 citations
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 • 47,043 citations
Small GTP-Binding Proteins
1992 • 526 citations
cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein
1993 • 322 citations
Role of Protein Modification Reactions in Programming Interactions Between Ras-Related GTPases and Cell Membranes
1994 • 279 citations
Rab proteins and the road maps for intracellular transport
1993 • 276 citations
The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins.
1991 • 230 citations
REP-2, a Rab escort protein encoded by the choroideremia-like gene.
1994 • 183 citations
C terminus of the small GTP-binding protein smg p25A contains two geranylgeranylated cysteine residues and a methyl ester.
1991 • 169 citations
Identification of a C-terminal protein carboxyl methyltransferase in rat liver membranes utilizing a synthetic farnesyl cysteine-containing peptide substrate.
1990 • 150 citations
Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export.
1994 • 110 citations
cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase
1993 • 94 citations
Characterization of a plasma membrane-associated prenylcysteine-directed alpha carboxyl methyltransferase in human neutrophils.
1994 • 71 citations
Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates
1992 • 70 citations
Post-translational processing of Schizosaccharomyces pombe YPT proteins.
1992 • 68 citations
A single activity carboxyl methylates both farnesyl and geranylgeranyl cysteine residues
1991 • 66 citations
Modification of eukaryotic signaling proteins by C-terminal methylation reactions
1993 • 57 citations
Kinetic mechanism of isoprenylated protein methyltransferase.
1992 • 48 citations
Identification of yeast component A: reconstitution of the geranylgeranyltransferase that modifies Ypt1p and Sec4p.
1994 • 42 citations
GTP-stimulated carboxyl methylation of a soluble form of the GTP-binding protein G25K in brain.
1992 • 41 citations
p23rab2, a ras-like GTPase with a -GGGCC C-terminus, is isoprenylated but not detectably carboxymethylated in NIH3T3 cells.
1992 • 35 citations
Post-translational Processing and Membrane Association of the Two Early Endosome-Associated rab GTP-Binding Proteins (rab4 and rab5)
1993 • 34 citations
Isolation and DNA sequence of the STE14 gene encoding farnesyl cysteine: Carboxyl methyltransferase
1993 • 31 citations
Nucleotide Sequence of the Yeast STE14 Gene, Which Encodes Farnesylcysteine Carboxyl Methyltransferase, and Demonstration of its Essential Role in a-Factor Export
1994 • 29 citations
Post-translational processing of Schizosaccharomyces pombe YPT5 protein. In vitro and in vivo analysis of processing mutants.
1993 • 22 citations