Phosphoinositide 3-kinase regulates β2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/β-arrestin complex

Synthesis and Function of 3-Phosphorylated Inositol Lipids

2001 • 1,527 citations

G PROTEIN–COUPLED RECEPTOR KINASES

1998 • 1,335 citations

β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor

1996 • 1,329 citations

PHOSPHOINOSITIDE KINASES

1998 • 1,321 citations

G Protein-coupled Receptors

1998 • 1,292 citations

G Protein-coupled Receptors

1998 • 1,033 citations

The Role of Phosphoinositide 3-Kinase Lipid Products in Cell Function

1999 • 1,007 citations

Role of β-Arrestin in Mediating Agonist-Promoted G Protein-Coupled Receptor Internalization

1996 • 938 citations

Seven-transmembrane-spanning receptors and heart function

2002 • 926 citations

CLATHRIN-COATED VESICLE FORMATION AND PROTEIN SORTING: An Integrated Process

1997 • 793 citations

Simultaneous Binding of PtdIns(4,5)P ₂ and Clathrin by AP180 in the Nucleation of Clathrin Lattices on Membranes

2001 • 719 citations

Cloning and Characterization of a G Protein-Activated Human Phosphoinositide-3 Kinase

1995 • 673 citations

Biological Basket Weaving: Formation and Function of Clathrin-Coated Vesicles

2001 • 626 citations

The β ₂ -adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis

1999 • 615 citations

PIP2 and PIP3

2000 • 538 citations

PHOSPHOINOSITIDE LIPIDS AS SIGNALING MOLECULES: Common Themes for Signal Transduction, Cytoskeletal Regulation, and Membrane Trafficking

1998 • 515 citations

Structural insights into phosphoinositide 3-kinase catalysis and signalling

1999 • 478 citations

Spatial control of coated-pit dynamics in living cells

1999 • 435 citations

The β -Adrenoceptor

1998 • 388 citations

The Interaction of β-Arrestin with the AP-2 Adaptor Is Required for the Clustering of β2-Adrenergic Receptor into Clathrin-coated Pits

2000 • 374 citations

Phosphoinositide–Ap-2 Interactions Required for Targeting to Plasma Membrane Clathrin-Coated Pits

1999 • 304 citations

Mechanism of β-Adrenergic Receptor Desensitization in Cardiac Hypertrophy Is Increased β-Adrenergic Receptor Kinase

1997 • 257 citations

Location, Location, Location: Membrane Targeting Directed by PX Domains

2001 • 237 citations

Synergistic Regulation of β₂-Adrenergic Receptor Sequestration: Intracellular Complement of β-Adrenergic Receptor Kinase and β-Arrestin Determine Kinetics of Internalization

1997 • 231 citations

Dynamin-dependent Transferrin Receptor Recycling by Endosome-derived Clathrin-coated Vesicles

2002 • 220 citations

Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes

1997 • 218 citations

The Class II Phosphoinositide 3-Kinase C2α Is Activated by Clathrin and Regulates Clathrin-Mediated Membrane Trafficking

2001 • 217 citations

Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding

1999 • 211 citations

Agonist-dependent Recruitment of Phosphoinositide 3-Kinase to the Membrane by β-Adrenergic Receptor Kinase 1

2001 • 180 citations

Angiotensin II Activates Phosphatidylinositol 3-Kinase in Vascular Smooth Muscle Cells

1997 • 172 citations

A Functional Phosphatidylinositol 3,4,5-Trisphosphate/Phosphoinositide Binding Domain in the Clathrin Adaptor AP-2 α Subunit. IMPLICATIONS FOR THE ENDOCYTIC PATHWAY

1996 • 162 citations

Functional Consequences of Altering Myocardial Adrenergic Receptor Signaling

2000 • 160 citations

PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1

1999 • 146 citations

Recruitment of Activated G Protein-coupled Receptors to Pre-existing Clathrin-coated Pits in Living Cells

2002 • 109 citations

Gastrin Stimulates Tyrosine Phosphorylation of Insulin Receptor Substrate 1 and Its Association with Grb2 and the Phosphatidylinositol 3-Kinase

1996 • 76 citations