Binding of NF-kB to the HIV-1 LTR Is Not Sufficient to Induce HIV-1 LTR Activity

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Complete nucleotide sequence of the AIDS virus, HTLV-III

1985 • 2,236 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

1989 • 1,660 citations

Turnover of Inositol Phospholipids and Signal Transduction

1984 • 1,629 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

Trans -Activator Gene of Human T-Lymphotropic Virus Type III (HTLV-III)

1985 • 872 citations

Activation of the AIDS Retrovirus Promoter by the Cellular Transcription Factor, Sp1

1986 • 741 citations

HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA

1986 • 673 citations

Location of the Trans -Activating Region on the Genome of Human T-Cell Lymphotropic Virus Type III

1985 • 558 citations

UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein.

1989 • 549 citations

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

1989 • 517 citations

Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA

1990 • 445 citations

Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter

1987 • 407 citations

Regulatory pathways governing HIV-1 replication

1989 • 401 citations

Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-1 long terminal repeat.

1989 • 357 citations

Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro.

1988 • 309 citations

Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events.

1987 • 246 citations

The HIV-1 Tat protein: An RNA sequence-specific processivity factor?

1990 • 220 citations

Role of SP1-binding domains in in vivo transcriptional regulation of the human immunodeficiency virus type 1 long terminal repeat

1989 • 188 citations

Transcriptional but not translational regulation of HIV-1 by the tat gene product

1988 • 158 citations

UV-induced transcription from the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and UV-induced secretion of an extracellular factor that induces HIV-1 transcription in nonirradiated cells

1989 • 119 citations

In vitro activation of the HIV-1 enhancer in extracts from cells treated with a phorbol ester tumor promoter.

1987 • 100 citations

Stimulation of a human T-cell clone with anti-CD3 or tumor necrosis factor induces NF-kappa B translocation but not human immunodeficiency virus 1 enhancer-dependent transcription.

1990 • 93 citations

Variable role of the long terminal repeat Sp1-binding sites in human immunodeficiency virus replication in T lymphocytes

1991 • 90 citations

The engelbreth-holm-swarm mouse tumor produces undersulfated heparan sulfate and oversulfated galactosaminoglycans

1989 • 75 citations

DNA and RNA virus species are inhibited by xanthates, a class of antiviral compounds with unique properties.

1984 • 65 citations

Trans-activation of the human immunodeficiency virus long terminal repeat sequences, expressed in an adenovirus vector, by the adenovirus E1A 13S protein.

1988 • 57 citations

Antibodies to recombinant HIV-1 vif, tat, and nef proteins in human sera

1990 • 42 citations

Inhibition of c-fos transcription and phosphorylation of the serum response factor by an inhibitor of phospholipase C-type reactions.

1990 • 30 citations

Reversion of bovine papillomavirus-induced transformation and immortalization by a xanthate compound

1985 • 28 citations

Inhibition of the Phosphorylation of the Regulatory Non-structural Protein of Vesicular Stomatitis Virus by an Antiviral Xanthate Compound

1987 • 27 citations

Inhibition of HIV-1 Replication by an Antiviral Xanthate Compound In Vitro

1988 • 23 citations

Interruption of growth signal transduction by an antiviral and antitumoral xanthate compound

1988 • 20 citations

Synergistic antiviral effect of xanthates and ionic detergents

1987 • 17 citations

Effects of the phorbolester TPA and of the ionophore A 23187 on phospholipase A2 and C activities in the mouse epidermal cell line HEL-30

1987 • 10 citations

The Therapeutic Efficacy of a Xanthate Compound on Herpes Simplex Virus in Skin Lesions of Mice and Guinea-pigs

1985 • 6 citations