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Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate

Data up to Jan 2025

Published2003
Citations664
References65
Clinical Trials (1)

Total Citations Per Year

Abstract

References (65)

Chondroitinase ABC promotes functional recovery after spinal cord injury

2002 • 2,236 citations

Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex

2002 • 1,592 citations

Specificities of heparan sulphate proteoglycans in developmental processes

2000 • 706 citations

Proteoglycans in the Developing Brain: New Conceptual Insights for Old Proteins

2000 • 619 citations

Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC

2001 • 562 citations

Dermatan sulfate: new functions from an old glycosaminoglycan

2002 • 429 citations

Pleiotrophin signals increased tyrosine phosphorylation of β-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase β/ζ

2000 • 415 citations

Chapter 22 Chondroitin sulphate proteoglycans in the CNS injury response

2002 • 415 citations

Midkine Binds to Anaplastic Lymphoma Kinase (ALK) and Acts as a Growth Factor for Different Cell Types

2002 • 349 citations

Specific Molecular Interactions of Oversulfated Chondroitin Sulfate E with Various Heparin-binding Growth Factors

2002 • 319 citations

Biosynthesis of Chondroitin/Dermatan Sulfate

2002 • 309 citations

Nervous tissue proteoglycans

1993 • 269 citations

Chondroitin proteoglycans are involved in cell division of Caenorhabditis elegans

2003 • 252 citations

Brevican-Deficient Mice Display Impaired Hippocampal CA1 Long-Term Potentiation but Show No Obvious Deficits in Learning and Memory

2002 • 247 citations

Heparin and Heparan Sulfate Biosynthesis

2002 • 246 citations

Oversulfated Chondroitin/Dermatan Sulfates Containing GlcAβ1/IdoAα1–3GalNAc(4,6-O-disulfate) Interact with L- and P-selectin and Chemokines

2002 • 237 citations

Endocan Is a Novel Chondroitin Sulfate/Dermatan Sulfate Proteoglycan That Promotes Hepatocyte Growth Factor/Scatter Factor Mitogenic Activity

2001 • 230 citations

Modification of extracellular matrix by enzymatic removal of chondroitin sulfate and by lack of tenascin-R differentially affects several forms of synaptic plasticity in the hippocampus

2001 • 229 citations

Caenorhabditis elegans early embryogenesis and vulval morphogenesis require chondroitin biosynthesis

2003 • 212 citations

Molecular Cloning and Expression of a Human Chondroitin Synthase

2001 • 202 citations

Neurocan Is Dispensable for Brain Development

2001 • 197 citations

The DSD-1 Carbohydrate Epitope Depends on Sulfation, Correlates with Chondroitin Sulfate D Motifs, and Is Sufficient to Promote Neurite Outgrowth

1998 • 180 citations

Molecular Interactions of Neural Chondroitin Sulfate Proteoglycans in the Brain Development

2000 • 165 citations

Molecular Cloning of a Chondroitin Polymerizing Factor That Cooperates with Chondroitin Synthase for Chondroitin Polymerization

2003 • 163 citations

Heparin-binding proteins HB-GAM (pleiotrophin) and amphoterin in the regulation of cell motility

2000 • 152 citations

Human Homolog of Caenorhabditis elegans sqv-3 Gene Is Galactosyltransferase I Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans

1999 • 139 citations

Neuronal Cell Adhesion, Mediated by the Heparin-binding Neuroregulatory Factor Midkine, Is Specifically Inhibited by Chondroitin Sulfate E

2000 • 133 citations

sqv mutants of Caenorhabditis elegans are defective in vulval epithelial invagination

1999 • 127 citations

Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase β

1998 • 126 citations

SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP- N - acetylgalactosamine, and UDP-galactose

2001 • 126 citations

sqv-3 , -7 , and - 8 , a set of genes affecting morphogenesis in Caenorhabditis elegans , encode enzymes required for glycosaminoglycan biosynthesis

2000 • 123 citations

Chondrodysplasias due to proteoglycan defects

2002 • 122 citations

Oversulfated Dermatan Sulfate Exhibits Neurite Outgrowth-promoting Activity toward Embryonic Mouse Hippocampal Neurons

2003 • 122 citations

Molecular Cloning and Expression of Human ChondroitinN-Acetylgalactosaminyltransferase

2002 • 120 citations

Decorin-binding proteins A and B confer distinct mammalian cell type-specific attachment by Borrelia burgdorferi , the Lyme disease spirochete

2003 • 120 citations

Molecular Cloning and Expression of a Second Chondroitin N-Acetylgalactosaminyltransferase Involved in the Initiation and Elongation of Chondroitin/Dermatan Sulfate

2003 • 110 citations

Chinese Hamster Ovary Cell Mutants Defective in Glycosaminoglycan Assembly and Glucuronosyltransferase I

1999 • 108 citations

Identification of GIT1/Cat-1 as a substrate molecule of protein tyrosine phosphatase ζ/β by the yeast substrate-trapping system

2001 • 107 citations

Demonstration of glycosaminoglycans in Caenorhabditis elegans

1999 • 106 citations

Dermatan Sulfate Binds and Potentiates Activity of Keratinocyte Growth Factor (FGF-7)

2002 • 104 citations

No Obvious Abnormality in Mice Deficient in Receptor Protein Tyrosine Phosphatase β

2000 • 103 citations

Heterogeneity of the Chondroitin Sulfate Portion of Phosphacan/6B4 Proteoglycan Regulates Its Binding Affinity for Pleiotrophin/Heparin Binding Growth-associated Molecule

2003 • 96 citations

A Chondroitin Sulfate Proteoglycan PTPζ/RPTPβ Regulates the Morphogenesis of Purkinje Cell Dendrites in the Developing Cerebellum

2003 • 92 citations

Structure and Function of Oversulfated Chondroitin Sulfate Variants. Unique Sulfation Patterns and Neuroregulatory Activities.

2000 • 89 citations

Phosphacan Short Isoform, a Novel Non-proteoglycan Variant of Phosphacan/Receptor Protein Tyrosine Phosphatase-β, Interacts with Neuronal Receptors and Promotes Neurite Outgrowth

2003 • 87 citations

Interactions between M proteins of Streptococcus pyogenes and glycosaminoglycans promote bacterial adhesion to host cells

2003 • 86 citations

Adaptation of the Lyme disease spirochaete to the mammalian host environment results in enhanced glycosaminoglycan and host cell binding

2003 • 85 citations

The Caenorhabditis elegans Genes sqv-2and sqv-6, Which Are Required for Vulval Morphogenesis, Encode Glycosaminoglycan Galactosyltransferase II and Xylosyltransferase

2003 • 85 citations

Enhanced bacterial virulence through exploitation of host glycosaminoglycans

2002 • 85 citations

The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development

2002 • 85 citations

Functional Analysis of the Chondroitin 6-Sulfotransferase Gene in Relation to Lymphocyte Subpopulations, Brain Development, and Oversulfated Chondroitin Sulfates

2002 • 84 citations

Glycosaminoglycan structures required for strong binding to midkine, a heparin-binding growth factor

2002 • 79 citations

Herpes simplex virus type 1 glycoprotein C is necessary for efficient infection of chondroitin sulfate-expressing gro2C cells

2002 • 77 citations

The Mode of Action of Heparan and Dermatan Sulfates in the Regulation of Hepatocyte Growth Factor/Scatter Factor

2002 • 77 citations

Molecular Cloning and Characterization of a Novel Chondroitin Sulfate Glucuronyltransferase That Transfers Glucuronic Acid toN-Acetylgalactosamine

2002 • 73 citations

TheCaenorhabditis elegansvulval morphogenesis genesqv-4encodes a UDP-glucose dehydrogenase that is temporally and spatially regulated

2002 • 71 citations

The Low Sulfated Chondroitin Sulfate Proteoglycans of Human Placenta Have Sulfate Group-clustered Domains That Can Efficiently Bind Plasmodium falciparum-infected Erythrocytes

2003 • 68 citations

The Structural Motif in Chondroitin Sulfate for Adhesion ofPlasmodium falciparum-infected Erythrocytes Comprises Disaccharide Units of 4-O-Sulfated and Non-sulfated N-Acetylgalactosamine Linked to Glucuronic Acid

2002 • 63 citations

Tenascin glycoproteins and the complementary ligand DSD-1-PG/ phosphacan--structuring the neural extracellular matrix during development and repair.

2001 • 59 citations

Molecular basis for the dichotomy in Plasmodium falciparum adhesion to CD36 and chondroitin sulfate A

2002 • 57 citations

Appican, the Proteoglycan Form of the Amyloid Precursor Protein, Contains Chondroitin Sulfate E in the Repeating Disaccharide Region and 4-O-Sulfated Galactose in the Linkage Region

2001 • 56 citations

Neuronal polarity: Giving neurons heads and tails

1995 • 54 citations

Roles of Proteoglycans in Reception of the Midkine Signal.

2001 • 11 citations

Roles of Proteoglycans in Neuronal Circuit Formation of Retinotectal Projections( Roles of Extracellular Matrix in the Development and Regeneration of Nervous Systems)

2003 • 7 citations

Signal Transduction of Proteoglycan-type Protein Tyrosine Phosphatase, PTPζ( Roles of Extracellular Matrix in the Development and Regeneration of Nervous Systems)

2003 • 4 citations

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Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate (2003) – Current Opinion in Structural Biology | Metascience Observatory Explorer