Chinese Hamster Ovary Cell Mutants Defective in Glycosaminoglycan Assembly and Glucuronosyltransferase I

PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSES

1954 • 3,832 citations

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1991 • 2,437 citations

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

1991 • 1,507 citations

Molecular modeling of protein-glycosaminoglycan interactions.

1989 • 1,288 citations

The Biochemistry of Glycoproteins and Proteoglycans

1980 • 1,231 citations

Glycosaminoglycans: molecular properties, protein interactions, and role in physiological processes

1991 • 1,088 citations

CLONAL GROWTH OF MAMMALIAN CELLS IN A CHEMICALLY DEFINED, SYNTHETIC MEDIUM

1965 • 833 citations

Animal cell mutants defective in glycosaminoglycan biosynthesis.

1985 • 587 citations

Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans.

1992 • 550 citations

Glycosaminoglycan-protein interactions: definition of consensus sites in glycosaminoglycan binding proteins

1998 • 541 citations

Heparin-Binding Proteins

1998 • 515 citations

The Putative Tumor Suppressors EXT1 and EXT2 Are Glycosyltransferases Required for the Biosynthesis of Heparan Sulfate

1998 • 425 citations

The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate

1998 • 377 citations

TRANSPORTERS OF NUCLEOTIDE SUGARS, ATP, AND NUCLEOTIDE SULFATE IN THE ENDOPLASMIC RETICULUM AND GOLGI APPARATUS

1998 • 377 citations

A single mutation affects both N-acetylglucosaminyltransferase and glucuronosyltransferase activities in a Chinese hamster ovary cell mutant defective in heparan sulfate biosynthesis.

1992 • 286 citations

Domain Structure of Heparan Sulfates from Bovine Organs

1996 • 281 citations

Multiple Isoforms of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase

1999 • 237 citations

Liver heparan sulfate structure. A novel molecular design

1994 • 235 citations

Genetic analysis of proteoglycan structure, function and metabolism

1991 • 230 citations

Heparin and Related Polysaccharides

1992 • 217 citations

Influence of core protein sequence on glycosaminoglycan assembly

1996 • 204 citations

Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains.

1994 • 199 citations

The Purification and Properties of β-Galactosidase from Bovine Testes

1973 • 199 citations

Inhibition of chondroitin and heparan sulfate biosynthesis in Chinese hamster ovary cell mutants defective in galactosyltransferase I.

1987 • 190 citations

Expression of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase Isoforms Reveals Novel Substrate Specificities

1999 • 180 citations

Undersulfated heparan sulfate in a Chinese hamster ovary cell mutant defective in heparan sulfate N-sulfotransferase

1989 • 171 citations

Molecular Cloning and Expression of Glucuronyltransferase I Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans

1998 • 171 citations

Molecular cloning and expression of rat liver N-heparan sulfate sulfotransferase.

1992 • 163 citations

Molecular Cloning and Expression of a Third Member of the Heparan Sulfate/Heparin GlcNAcN-Deacetylase/N-Sulfotransferase Family

1999 • 161 citations

Molecular Cloning and Expression of Mouse and Human cDNAs Encoding Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase

1997 • 159 citations

Herpes simplex virus infection and propagation in a mouse L cell mutant lacking heparan sulfate proteoglycans

1993 • 156 citations

Molecular cloning and expression of a glycosaminoglycan N-acetylglucosaminyl N-deacetylase/N-sulfotransferase from a heparin-producing cell line.

1994 • 152 citations

cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an enzyme involved in the biosynthesis of heparin.

1994 • 151 citations

Presence of N-Unsubstituted Glucosamine Units in Native Heparan Sulfate Revealed by a Monoclonal Antibody

1995 • 147 citations

Phosphorylation of chondroitin sulfate in proteoglycans from the swarm rat chondrosarcoma.

1984 • 141 citations

Sequential isolation of proteoglycan synthesis mutants by using herpes simplex virus as a selective agent: evidence for a proteoglycan-independent virus entry pathway

1995 • 141 citations

Biosynthesis of heparan sulfate on beta-D-xylosides depends on aglycone structure.

1994 • 137 citations

An Animal Cell Mutant Defective in Heparan Sulfate Hexuronic Acid 2- -Sulfation

1996 • 132 citations

Sulfate transport-deficient mutants of Chinese hamster ovary cells. Sulfation of glycosaminoglycans dependent on cysteine.

1986 • 130 citations

Cloning and functional expression of a novel glucuronyltransferase involved in the biosynthesis of the carbohydrate epitope HNK-1

1997 • 129 citations

Structural studies on sulfated glycopeptides from the carbohydrate-protein linkage region of chondroitin 4-sulfate proteoglycans of swarm rat chondrosarcoma. Demonstration of the structure Gal(4-O-sulfate)beta 1-3Gal beta 1-4XYL beta 1-O-Ser.

1988 • 123 citations

Structural differences of heparan sulfates according to the tissue and species of origin

1983 • 114 citations

Transporters of nucleotide sugars, nucleotide sulfate and ATP in the Golgi apparatus

1997 • 111 citations

Structure of the heparan sulfate-protein linkage region. Demonstration of the sequence galactosyl-galactosyl-xylose-2-phosphate.

1985 • 104 citations

Molecular Characterization and Expression of Heparan-sulfate 6-Sulfotransferase

1998 • 101 citations

Biosynthesis of the Chondroitin Sulfate Proteoglycan

1972 • 101 citations

Biosynthesis of Chondroitin Sulfate Proteoglycan

1972 • 100 citations

Topography of glycosylation and UDP-xylose production

1993 • 91 citations

Sulfated N-linked oligosaccharides in mammalian cells. I. Complex-type chains with sialic acids and O-sulfate esters.

1988 • 90 citations

Identification and Expression in Mouse of Two Heparan Sulfate Glucosaminyl N-Deacetylase/N-Sulfotransferase Genes

1998 • 85 citations

Xylosylation and glucuronosylation reactions in rat liver Golgi apparatus and endoplasmic reticulum.

1986 • 77 citations

Two N-acetylgalactosaminyltransferase are involved in the biosynthesis of chondroitin sulfate

1985 • 73 citations

Structural Studies on the Hexasaccharide Alditols Isolated from the Carbohydrate-Protein Linkage Region of Dermatan Sulfate Proteoglycans of Bovine Aorta

1995 • 71 citations

Identification of a Novel Glycosaminoglycan Core-like Molecule I

1995 • 64 citations

Structure of heparan sulfate: identification of variable and constant oligosaccharide domains in eight heparan sulfates of different origins.

1998 • 64 citations

Two N-acetylglucosaminyltransferases catalyze the biosynthesis of heparan sulfate.

1994 • 63 citations

Structural analysis of the linkage region oligosaccharides and unsaturated disaccharides from chondroitin sulfate using CarboPac PA1.

1992 • 63 citations

Alpha- and beta-xylosides alter glycolipid synthesis in human melanoma and Chinese hamster ovary cells.

1993 • 61 citations

Expression and activities of a recombinant basic fibroblast growth factor-saporin fusion protein.

1994 • 55 citations

Formation of HNK-1 Determinants and the Glycosaminoglycan Tetrasaccharide Linkage Region by UDP-GlcUA:Galactose β1,3-Glucuronosyltransferases

1999 • 53 citations

Biosynthesis of the Proteoglycan Decorin Transient 2‐Phosphorylation of Xylose during Formation of the Trisaccharide Linkage Region

1997 • 53 citations

Reconstitution into proteoliposomes and partial purification of the Golgi apparatus membrane UDP-galactose, UDP-xylose, and UDP-glucuronic acid transport activities.

1992 • 47 citations

The Uniform Galactose 4‐Sulfate Structure in the Carbohydrate‐Protein Linkage Region of Human Urinary Trypsin Inhibitor

1995 • 45 citations

Characterization of a cell mutant specifically defective in the synthesis of anticoagulantly active heparan sulfate.

1994 • 42 citations

N-Acetylgalactosamine (GalNAc) Transfer to the Common Carbohydrate-Protein Linkage Region of Sulfated Glycosaminoglycans

1995 • 42 citations

Characterization of β-D-Xyloside-Induced Glycosaminoglycans and Oligosaccharides in Cultured Human Skin Fibroblasts1

1991 • 40 citations

Variations in the Chondroitin Sulfate-Protein Linkage Region of Aggrecans from Bovine Nasal and Human Articular Cartilages

1996 • 38 citations

The sulphated carbohydrate-protein linkage region isolated from chondroitin 4-sulphate chains of inter-α-trypsin inhibitor in human plasma

1995 • 35 citations

Post-translational phosphorylation of proteodermatan sulfate.

1986 • 33 citations

Polydispersity in Sulfation Profile of Oligosaccharide Alditols Isolated from the Protein‐Linkage Region and the Repeating Disaccharide Region of Chondroitin 4‐Sulfate of Bovine Nasal Septal Cartilage

1996 • 29 citations

Cell mutants defective in synthesizing a heparan sulfate proteoglycan with regions of defined monosaccharide sequence.

1990 • 27 citations

Disaccharide Composition of Heparan Sulfates: Brain, Nervous Tissue Storage Organelles, Kidney, and Lung

1994 • 27 citations

Chapter 17 Replica Plating of Animal Cells

1989 • 26 citations

UDP-glucuronate carboxy-lyase in cultured chondrocytes.

1977 • 24 citations

HNK-1-reactive Novel Oligosaccharide, Sulfate-O-3GlcAβ1– 4Xylβ1-(4-methylumbelliferone), Synthesized by Cultured Human Skin Fibroblasts

1995 • 23 citations

Identification of a Novel Glycosaminoglycan Core-like Molecule II

1995 • 22 citations

A novel oligosaccharide, GlcAβ1-4Xylβ1-(4-methylumbelliferone), synthesized by human cultured skin fibroblasts

1994 • 21 citations

Assessment of glycosaminoglycan-protein linkage tetrasaccharides as acceptors for GalNAc- and GlcNAc-transferases from mouse mastocytoma.

1997 • 21 citations

Chinese hamster ovary cell mutants deficient in an anion exchanger functionally similar to the erythroid band 3.

1988 • 19 citations

Structural variations in the glycosaminoglycan-protein linkage region of recombinant decorin expressed in Chinese hamster ovary cells

1997 • 19 citations

-N-Acetylgalactosamine-capping of chondroitin sulfate core region oligosaccharides primed on xylosides

1998 • 19 citations

A Novel Oligosaccharide, Xylosylβl-4Xylosylβ1-(4-Methylumbelliferone), Synthesized by Cultured Human Skin Fibroblasts in the Presence of 4-Methylumbelliferyl-β-D-Xyloside1

1994 • 18 citations

Secretion of unphosphorylated and phosphorylated xyloside-induced glycosaminoglycan chains

1988 • 14 citations

Characterization and Biological Significance of Sialyl 2-3Galactosyl 1-4Xylosyl l-(4-Methylumbelliferone) Synthesized in Cultured Human Skin Fibroblasts

1996 • 10 citations

Expression and Characterization of a Basic Fibroblast Growth Factor‐Saporin Fusion Protein in Escherichia coli^a

1991 • 8 citations