Lack of Cross-Tolerance for Hypophagia Induced by DOI versus m-CPP Suggests Separate Mediation by 5-HT2A and 5-HT2C Receptors, Respectively

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

1982 • 1,049 citations

Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor

1988 • 691 citations

The binding of serotonergic ligands to the porcine choroid plexus: Characterization of a new type of serotonin recognition site

1984 • 598 citations

A proposed new nomenclature for 5-HT receptors

1993 • 551 citations

Structure and functional expression of cloned rat serotonin 5HT-2 receptor.

1988 • 381 citations

Radioligand binding evidence implicates the brain 5-HT2 receptor as a site of action for LSD and phenylisopropylamine hallucinogens

1988 • 334 citations

m-Chlorophenylpiperazine: A central serotonin agonist causing powerful anorexia in rats

1979 • 221 citations

Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors.

1987 • 217 citations

Serotonin-selective arylpiperazines with neuroendocrine, behavioral, temperature, and cardiovascular effects in humans.

1991 • 216 citations

Molecular biology of 5-HT receptors

1989 • 214 citations

Autoradiographic characterization of (+-)-1-(2,5-dimethoxy-4-[125I] iodophenyl)-2-aminopropane ([125I]DOI) binding to 5-HT2 and 5-HT1c receptors in rat brain.

1990 • 175 citations

A quantitative autoradiographic study of serotonin1A receptor regulation. Effect of 5,7-dihydroxytryptamine and antidepressant treatments.

1991 • 175 citations

Involvement of 5-HT1C-receptors in drug-induced penile erections in rats

1990 • 151 citations

Potencies of antagonists indicate that 5‐HT_1C receptors mediate 1–3(chlorophenyl)piperazine‐induced hypophagia

1991 • 150 citations

Serotonin-releasing effects of substituted piperazines in vitro

1984 • 104 citations

5-HT1C receptor-mediated stimulation of inositol phosphate production in pig choroid plexus

1989 • 102 citations

Iodine-125 labeled 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane: an iodinated radioligand that specifically labels the agonist high-affinity state of 5-HT2 serotonin receptors

1988 • 97 citations

Food deprivation increases brain nitric oxide synthase and depresses brain serotonin levels in rats

1994 • 92 citations

1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI) exerts an anorexic action that is blocked by 5-HT2 antagonists in rats

1988 • 81 citations

Hyper- and hyposensitivity of central serotonin receptors: [3H]serotonin binding and functional studies in the rat

1980 • 78 citations

Discriminative stimulus properties of the serotonergic agent 1-(2, 5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)

1986 • 70 citations

Problems in in vitro receptor binding studies and identification and role of serotonin receptor sites

1984 • 65 citations

Effects of various serotonin receptor subtype-selective antagonists alone and on m-chlorophenylpiperazine-induced neuroendocrine changes in rats.

1992 • 59 citations

Novel regulation of 5-HT1C receptors: down-regulation induced both by 5-HT1C/2 receptor agonists and antagonists

1993 • 55 citations

Development of selective tolerance to the serotonin behavioral syndrome and suppression of locomotor activity after repeated administration of either 5-MeODMT or mCPP

1985 • 54 citations

Intravenous administration of the serotonin agonist m-chlorophenylpiperazine (mCPP) increases extracellular serotonin in the diencephalon of awake rats

1993 • 51 citations

Denervation supersensitivity of 5-HT-1c receptors in rat choroid plexus

1987 • 49 citations

Properties of some 1-arylpiperazines as antagonists of stereotyped behaviors mediated by central serotonergic receptors in rodents.

1988 • 48 citations

The 5-HT transporter is an additional site of action for the 5-HT agonists RU 24969 and TFMPP

1991 • 41 citations

Regulation of 5-HT2 receptors in rat cortex

1991 • 40 citations

Long-term administration of m-chlorophenylpiperazine (mCPP) to rats induces changes in serotonin receptor binding, dopamine levels and locomotor activity without altering prolactin and corticosterone secretion

1992 • 37 citations

Regional analysis of 5-HT1A and 5-HT2 receptors in the Fawn-Hooded rat

1992 • 32 citations

Evidence for involvement of 5-HT1C and 5-HT2 receptors in the food intake suppressant effects of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)

1992 • 28 citations

Effect of 5,7-dihydroxytryptamine lesion on mianserin-induced conditioned place aversion and on 5-hydroxytryptamine1C receptors in the rat brain

1993 • 26 citations

Analysis of the 5-HT1C receptor and the serotonin uptake site in Fawn-Hooded rat brain

1993 • 25 citations

Molecular biology of 5-HT, receptors

1993 • 13 citations

Differential effects of chronic antidepressant treatment on 5-HT1C receptor binding sites in Wistar rat brain

1994 • 8 citations