Long-term administration of m-chlorophenylpiperazine (mCPP) to rats induces changes in serotonin receptor binding, dopamine levels and locomotor activity without altering prolactin and corticosterone secretion

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

1980 • 840 citations

Functional Correlates of Serotonin 5-HT₁Recognition Sites

1988 • 564 citations

Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro.

1987 • 550 citations

[³H]8‐Hydroxy‐2‐(Di‐n‐Propylamino)Tetralin Binding to Pre‐ and Postsynaptic 5‐Hydroxytryptamine Sites in Various Regions of the Rat Brain

1985 • 458 citations

Pharmacological Differentiation and Characterization of 5‐HT_1A, 5‐HT_1B, and 5‐HT_1C Binding Sites in Rat Frontal Cortex

1986 • 344 citations

Characterization of the 5-HTIB recognition site in rat brain: Binding studies with (−)[125I]Iodocyanopindolol

1985 • 281 citations

m-Chlorophenylpiperazine: A central serotonin agonist causing powerful anorexia in rats

1979 • 221 citations

Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors.

1987 • 217 citations

Two distinct effects of 5-hydroxytryptamine on single cortical neurons

1987 • 197 citations

Chronic treatment with antidepressants prevents the inhibitory effect of small doses of apomorphine on dopamine synthesis and motor activity

1979 • 193 citations

Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl)piperazine on locomotor activity.

1989 • 189 citations

Depression in Patients with Parkinsonism

1976 • 187 citations

Autoradiographic quantification of serotonin_1A receptors in rat brain following antidepressant drug treatment

1989 • 185 citations

Neuroendocrine Effects ofM-Chlorophenylpiperazine, a Serotonin Agonist, in Humans

1985 • 181 citations

Electroconvulsive Shock: Progressive Dopamine Autoreceptor Subsensitivity Independent of Repeated Treatment

1980 • 155 citations

Disposition and pharmacological effects of m-Chlorophenylpiperazine in rats

1981 • 127 citations

Effect of chronic antidepressant treatment and subsequent withdrawal on [3H]-5-hydroxytryptamine and [3H]-spiperone binding in rat frontal cortex and serotonin receptor mediated behaviour

1983 • 126 citations

(—)-m-Chlorophenyl-piperazine, a central 5-hydroxytryptamine agonist, is a metabolite of trazodone

1981 • 111 citations

Application of [125I]iodocyanopindolol to measure 5-hydroxytryptamine1B receptors in the brain of the rat.

1988 • 94 citations

Guanyl Nucleotide and Divalent Cation Regulation of Cortical S₂ Serotonin Receptors

1984 • 82 citations

Neuroendocrine and behavioral effects of m-chlorophenylpiperazine administration in rhesus monkeys

1984 • 73 citations

Spiperone differentiates multiple 5-hydroxytryptamine responses in rat hippocampal slices in vitro

1985 • 66 citations

Differential Neuroendocrine Responses to the 5-HT Agonist m-Chlorophenylpiperazine in Fawn-Hooded Rats Relative to Wistar and Sprague-Dawley Rats

1988 • 61 citations

Effects of m-chlorophenylpiperazine on receptor binding and brain metabolism of monoamines in rats

1981 • 59 citations

Pharmacological evidence of supersensitivity of central serotonergic receptors involved in the control of prolactin secretion

1981 • 58 citations

Development of selective tolerance to the serotonin behavioral syndrome and suppression of locomotor activity after repeated administration of either 5-MeODMT or mCPP

1985 • 54 citations

Serotonin receptor changes after chronic antidepressant treatments: Ligand binding, electrophysiological, and behavioral studies

1983 • 53 citations

Chronic effects of imipramine and lithium on 5-HT receptor subtypes in rat frontal cortex, hippocampus and choroid plexus: Quantitative receptor autoradiographic analysis.

1989 • 43 citations

Regulation of Serotonin Receptors and Responsiveness in the Brain

1988 • 40 citations

Down-regulation of serotonin2 but not of beta-adrenergic receptors during chronic treatment with amitriptyline is independent of stimulation of serotonin2 and beta-adrenergic receptors

1986 • 38 citations

Long‐term imipramine treatment enhances locomotor and food intake suppressant effects of m‐chlorophenylpiperazine in rats

1987 • 35 citations

Tricyclic antidepressants induce subsensitivity of presynaptic dopamine autoreceptors

1980 • 32 citations

Effects of daily oral m-Chlorophenylpiperazine in elderly depressed patients initial experience with a serotonin agonist

1990 • 26 citations

Analysis of trazodone and m-chlorophenylpiperazine in plasma and brain tissue by high-performance liquid chromatography

1986 • 26 citations

Electrophysiological Investigation of the Effects of Antidepressant Treatments on Serotonin Receptors

1990 • 9 citations

Serotonin in Depression and Anxiety

1990 • 7 citations

Long-term imipramine treatment potentiates m-chlorophenylpiperazine-induced changes in prolactin but not corticosterone or growth hormone levels in rats

1989 • 6 citations

Biphasic effects of m-chlorophenyl-piperazine on 3,4-dihydroxyphenylacetic acid concentration in rat brain.

1977 • 5 citations