Transforming growth factor beta as a potential tumor progression factor among hyperdiploid glioblastoma cultures: evidence for the role of platelet-derived growth factor.

THE UNLABELED ANTIBODY ENZYME METHOD OF IMMUNOHISTOCHEMISTRY PREPARATION AND PROPERTIES OF SOLUBLE ANTIGEN-ANTIBODY COMPLEX (HORSERADISH PEROXIDASE-ANTIHORSERADISH PEROXIDASE) AND ITS USE IN IDENTIFICATION OF SPIROCHETES

1970 • 5,141 citations

pl Bl5: A cDNA Clone of the Rat mRNA Encoding Cyclophilin

1988 • 1,039 citations

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

1987 • 998 citations

Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation

1990 • 812 citations

TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

1990 • 756 citations

Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development.

1991 • 677 citations

TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains

1990 • 612 citations

A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma.

1985 • 607 citations

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

1986 • 541 citations

The murine transforming growth factor-beta precursor.

1986 • 492 citations

Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation

1992 • 486 citations

Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential.

1990 • 398 citations

Cellular transformation by coordinated action of three peptide growth factors from human platelets

1984 • 383 citations

Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class.

1988 • 314 citations

Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors

1994 • 304 citations

Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation.

1988 • 288 citations

Alterations of the TP53 gene in human gliomas.

1994 • 246 citations

Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer.

1992 • 237 citations

Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets

1990 • 226 citations

The retinoblastoma gene is involved in malignant progression of astrocytomas

1994 • 220 citations

Murine Transforming Growth Factor-β2 cDNA Sequence and Expression in Adult Tissues and Embryos

1989 • 220 citations

Platelet-derived growth factor receptor-beta is induced during tumor development and upregulated during tumor progression in endothelial cells in human gliomas.

1992 • 202 citations

Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation

1991 • 196 citations

A v-erbB-related protooncogene, c-erb-B-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma

1985 • 195 citations

Type beta transforming growth factor/growth inhibitor stimulates entry of monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval.

1985 • 191 citations

Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts.

1992 • 181 citations

High levels of transforming growth factor beta 1 correlate with disease progression in human colon cancer.

1995 • 179 citations

Transforming growth factor β stimulates mamary adenocarcinoma cell invasion and metastasis potential

1990 • 164 citations

Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1.

1992 • 155 citations

TGF‐β stimulates primary human skin fibroblast DNA synthesis via an autocrine production of PDGF‐related peptides

1989 • 154 citations

Human keratinocytes are a major source of cutaneous platelet-derived growth factor.

1993 • 149 citations

The effect of transforming growth factor-β2-specific phosphorothioate-anti-sense oligodeoxynucleotides in reversing cellular immunosuppression in malignant glioma

1993 • 142 citations

Growth Factor Synthesis and Human Breast Cancer Progression

1995 • 140 citations

Chromosomal evolution in malignant human gliomas starts with specific and usually numerical deviations

1986 • 139 citations

Transforming growth factor beta 1 can induce estrogen-independent tumorigenicity of human breast cancer cells in athymic mice.

1993 • 138 citations

Differential regulation of expression of two platelet-derived growth factor receptor subunits by transforming growth factor-β

1989 • 136 citations

Agents that increase cAMP accumulation block endothelial c-sis induction by thrombin and transforming growth factor-beta.

1987 • 126 citations

A Correlative Study of p53 Protein Alteration and p53 Gene Mutation in Glioblastoma Multiforme

1993 • 119 citations

Loss of growth factor dependence and conversion of transforming growth factor-beta 1 inhibition to stimulation in metastatic H-ras-transformed murine fibroblasts.

1988 • 113 citations

Transforming growth factor‐βs inhibit mitogen‐stimulated proliferation of astrocytes

1993 • 109 citations

TGFβ₁ and TGFβ₂ are potential growth regulators for low‐grade and malignant gliomas in vitro: Evidence in support of an autocrine hypothesis

1991 • 107 citations

Synthesis, phosphorylation, and degradation of multiple forms of the platelet-derived growth factor receptor studied using a monoclonal antibody.

1987 • 102 citations

Transforming growth factor-β1 regulates platelet-derived growth factor receptor β subunit in human liver fat-storing cells

1995 • 99 citations

Expression of multi-cytokine resistance and multi-growth factor independence in advanced stage metastatic cancer. Malignant melanoma as a paradigm.

1992 • 89 citations

Mitogenic effect of transforming growth factor β1 on human fibroblasts involves the induction of platelet‐derived growth factor α receptors

1990 • 88 citations

Regulation of platelet-derived growth factor gene expression by transforming growth factor beta and phorbol ester in human leukemia cell lines.

1987 • 86 citations

Development of resistance mechanisms to the growth-inhibitory effects of transforming growth factor-beta during tumor progression.

1993 • 86 citations

Effects of Transforming Growth Factor β1 on Astroglial Cells in Culture

1990 • 85 citations

Control of astrocytosis by interleukin-1 and transforming growth factor-β1 in human brain

1993 • 77 citations

Response of low-passage human malignant gliomas in vitro to stimulation and selective inhibition of growth factor-mediated pathways

1991 • 75 citations

Transforming growth factor β‐1 positively modulates the bioactivity of fibroblast growth factor on corneal endothelial cells

1989 • 73 citations

Transforming growth factor‐β1 inhibits the proliferation of rat astrocytes induced by serum and growth factors

1995 • 69 citations

Platelet Derived Growth Factor (PDGF) autocrine components in human tumor cell lines

1990 • 69 citations

Transforming growth factor β1 is a powerful modulator of platelet‐derived growth factor action in vascular smooth muscle cells

1992 • 64 citations

Progression of Colorectal Cancer Is Associated with Multiple Tumor Suppressor Gene Defects but Inhibition of Tumorigenicity Is Accomplished by Correction of Any Single Defect via Chromosome Transfer

1992 • 64 citations

Transforming growth factor β1 treatment of AKR-2B cells is coupled through a pertussis-toxin-sensitive G-protein(s)

1989 • 57 citations

Prognostic value of cytogenetic analysis in human cerebral astrocytomas

1992 • 52 citations

Transforming Growth Factor-β Induces Platelet-Derived Growth Factor (PDGF) Messenger RNA and PDGF Secretion while Inhibiting Growth in Normal Human Mammary Epithelial Cells

1990 • 50 citations

Identification of a soluble receptor for platelet-derived growth factor in cell-conditioned medium and human plasma

1993 • 49 citations

Regulation of neuroendocrine peptide gene expression

1989 • 47 citations

Differential effects of transforming growth factor beta 1 on the growth of poorly and highly metastatic murine melanoma cells.

1990 • 44 citations

TGFβ1 and TGFβ2 are potential growth regulators for medulloblastomas, primitive neuroectodermal tumors, and ependymomas: Evidence in support of an autocrine hypothesis

1994 • 38 citations

Retinoic acid induces secretion of latent transforming growth factor beta 1 and beta 2 in normal and human papillomavirus type 16-immortalized human keratinocytes.

1992 • 37 citations

Control of the expression of c-sis mRNA in human glioblastoma cells by phorbol ester and transforming growth factor beta 1.

1989 • 34 citations

Expression of platelet-derived growth factor and transforming growth factor and their correlation with cellular morphology in glial tumors

1991 • 34 citations

Transforming growth factor beta stimulates phosphoinositol metabolism and translocation of protein kinase C in cultured astrocytes

1988 • 32 citations

The effects of type beta transforming growth factor on proliferation and epidermal growth factor receptor expression in a human glioblastoma cell line

1988 • 31 citations

Immunophenotypic differences between normal glia, astrocytomas and malignant gliomas: correlations with karyotype, natural history and survival

1989 • 28 citations

Expression of multi-cytokine resistance and multi-growth factor independence in advanced stage metastatic cancer. Malignant melanoma as a paradigm.

1992 • 26 citations

Reduction of TGF‐beta activity abrogates growth promoting tumor cell‐cell interactions in vivo

1991 • 26 citations

Interaction of acidic fibroblast growth factor and transforming growth factor-β in normal and transformed glia in vitro

1992 • 20 citations

Phenotypic alterations in fibroblasts and fibrosarcoma cells that overexpress latent transforming growth factor-beta 1.

1992 • 16 citations

Regulation of Platelet-Derived Growth Factor Gene Expression by Transforming Growth Factor β and Phorbol Ester in Human Leukemia Cell Lines

1987 • 14 citations

EFFECT OF TRANSFORMING GROWTH FACTOR‐β1 ON PLATELET‐DERIVED GROWTH FACTOR RECEPTOR BINDING AND GENE EXPRESSION IN VASCULAR SMOOTH MUSCLE CELLS FROM SHR AND WKY RATS

1994 • 13 citations

Five novel cell surface antigens of CNS neoplasms

1989 • 12 citations

DNA index and S-phase in primary brain tumors

1994 • 10 citations

Factor analysis of the immunophenotypes of astrocytomas and malignant gliomas: Correlations with tumor grade and patient survival

1990 • 8 citations

Deleted Work

1955 • 0 citations

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