Expression of VEGF‐C and VEGF‐D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1

1996 • 3,851 citations

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

1996 • 1,670 citations

Molecular and Biological Properties of the Vascular Endothelial Growth Factor Family of Proteins

1992 • 1,612 citations

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

1995 • 1,421 citations

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

2001 • 1,217 citations

Interleukin 6 Induces the Expression of Vascular Endothelial Growth Factor

1996 • 1,031 citations

Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors.

1992 • 900 citations

The Spread of Rectal Cancer and its Effect on Prognosis

1958 • 807 citations

Tumor-Associated Macrophages Express Lymphatic Endothelial Growth Factors and Are Related to Peritumoral Lymphangiogenesis

2002 • 778 citations

Proteolytic processing regulates receptor specificity and activity of VEGF-C

1997 • 773 citations

Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells.

1994 • 702 citations

Vascular endothelial growth factor C induces angiogenesis in vivo

1998 • 558 citations

VEGFR-3 and Its Ligand VEGF-C Are Associated with Angiogenesis in Breast Cancer

1999 • 550 citations

VEGFs, receptors and angiogenesis

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A multivariate analysis of clinical and pathological variables in prognosis after resection of large bowel cancer

1985 • 467 citations

Proinflammatory Cytokines Regulate Expression of the Lymphatic Endothelial Mitogen Vascular Endothelial Growth Factor-C

1998 • 404 citations

Expression of Angiogenesis Stimulators and Inhibitors in Human Thyroid Tumors and Correlation with Clinical Pathological Features

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Induction of Vascular Endothelial Growth Factor Gene Expression by Interleukin-1 β in Rat Aortic Smooth Muscle Cells

1995 • 347 citations

The Mouse Gene for Vascular Endothelial Growth Factor

1996 • 335 citations

Biosynthesis of Vascular Endothelial Growth Factor-D Involves Proteolytic Processing Which Generates Non-covalent Homodimers

1999 • 330 citations

Vascular Endothelial Growth Factors VEGF-B and VEGF-C Are Expressed in Human Tumors

1998 • 328 citations

Identification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor family.

1996 • 315 citations

Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer.

1999 • 313 citations

Expression of vascular endothelial growth factors A, B, C, and D and their relationships to lymph node status in lung adenocarcinoma.

2000 • 288 citations

Vascular endothelial growth factor-C expression in human prostatic carcinoma and its relationship to lymph node metastasis

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The relationship of survival to staging and grading of colorectal carcinoma: A prospective study of 503 cases

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Expression of vascular endothelial growth factor family members in head and neck squamous cell carcinoma correlates with lymph node metastasis

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VEGF-A, VEGF-C, and VEGF-D in Colorectal Cancer Progression

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Clinicopathological significance of vascular endothelial growth factor (VEGF)-C in human esophageal squamous cell carcinomas

2001 • 193 citations

PREDICTION OF OUTCOME AFTER CURATIVE RESECTION FOR LARGE BOWEL CANCER

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Slowed Release of Thrombin-cleaved Factor VIII from von Willebrand Factor by a Monoclonal and a Human Antibody Is a Novel Mechanism for Factor VIII Inhibition

1996 • 175 citations

Expression of Vascular Endothelial Growth Factor (VEGF) Family Members in Breast Cancer

1999 • 174 citations

Endoscopic treatment of submucosal invasive colorectal carcinoma with special reference to risk factors for lymph node metastasis

1995 • 171 citations

The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor.

1993 • 164 citations

Localization of vascular endothelial growth factor-D in malignant melanoma suggests a role in tumour angiogenesis

2001 • 143 citations

Vascular endothelial growth factor-C expression predicts lymph node metastasis of human gastric carcinomas invading the submucosa

2002 • 127 citations

Clinical Significance of Vascular Endothelial Growth Factor C Expression and Angiogenesis at the Deepest Invasive Site of Advanced Colorectal Carcinoma

2002 • 110 citations

In Fibroblasts Vegf-D Expression Is Induced by Cell-Cell Contact Mediated by Cadherin-11

2001 • 87 citations

Proliferating Cell Nuclear Antigen Expression Correlates with the Metastatic Potential of Submucosal Invasive Colorectal Carcinoma

1995 • 52 citations

Significance of angiogenic factors in liver metastatic tumors originating from colorectal cancers.

1998 • 43 citations

Angiogenesis at the site of deepest penetration predicts lymph node metastasis of submucosal colorectal cancer

2001 • 42 citations

Cathepsin D expression as a possible predictor of lymph node metastasis in submucosal colorectal cancer

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Evolution of Mirizzi syndrome with biliobiliary fistula

1995 • 26 citations

Hypoxia Up-regulates Mouse Vascular Endothelial Growth Factor D Promoter Activity in Rat Pulmonary Microvascular Smooth-Muscle Cells

2002 • 22 citations