NGF induction of the gene encoding the protease transin accompanies neuronal differentiation in PC12 cells

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Growth of a rat neuroblastoma cell line in serum-free supplemented medium.

1979 • 2,285 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1989 • 1,414 citations

Epidermal Growth Factor and a New Derivative

1972 • 1,225 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

1989 • 1,087 citations

pl Bl5: A cDNA Clone of the Rat mRNA Encoding Cyclophilin

1988 • 1,039 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene

1988 • 661 citations

Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein.

1986 • 645 citations

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

1985 • 506 citations

Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids.

1978 • 468 citations

Comparison of human stromelysin and collagenase by cloning and sequence analysis

1986 • 443 citations

Environmental influences in the development of neural crest derivatives: glucocorticoids, growth factors, and chromaffin cell plasticity

1985 • 406 citations

Plasminogen Activator Release at the Neuronal Growth Cone

1981 • 388 citations

The collagenase gene family in humans consists of at least four members

1988 • 364 citations

Acidic and basic fibroblast growth factors promote stable neurite outgrowth and neuronal differentiation in cultures of PC12 cells

1987 • 353 citations

Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts.

1985 • 344 citations

Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.

1986 • 339 citations

A bipotential neuroendocrine precursor whose choice of cell fate is determined by NGF and glucocorticoids

1986 • 337 citations

Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth

1988 • 337 citations

Growth Factors Regulate Transin Gene Expression by c- fos -Dependent and c- fos -Independent Pathways

1988 • 290 citations

The effect of fibroblast growth factor on PC12 cells

1985 • 270 citations

Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells.

1987 • 267 citations

The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors.

1986 • 260 citations

The NGF-inducible SCG10 mRNA encodes a novel membrane-bound protein present in growth cones and abundant in developing neurons

1988 • 239 citations

Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effect of antiserum to nerve growth factor.

1979 • 225 citations

Release of plasminogen activator and a calcium-dependent metalloprotease from cultured sympathetic and sensory neurons

1985 • 221 citations

Transcription from the stromelysin promoter is induced by interleukin-1 and repressed by dexamethasone.

1987 • 217 citations

Plasminogen activator secretion by granule neurons in cultures of developing cerebellum.

1981 • 188 citations

Identification of a Cyclic Adenosine Monophosphate-Responsive Element in the Rat Corticotropin-Releasing Hormone Gene

1988 • 187 citations

Dual regulation of GAP-43 gene expression by nerve growth factor and glucocorticoids.

1988 • 181 citations

Cloning and developmental expression of the murine neurofilament gene family

1986 • 180 citations

Glucocorticoid-modulated gene expression of tissue- and urinary-type plasminogen activator and plasminogen activator inhibitor 1 and 2.

1988 • 168 citations

Structure of the NGFI-A gene and detection of upstream sequences responsible for its transcriptional induction by nerve growth factor.

1989 • 164 citations

On the importance of being inhibited, or saying no to growth cones

1988 • 158 citations

Transcriptional and post-transcriptional effects of nerve growth factor on expression of the three neurofilament subunits in PC-12 cells.

1988 • 153 citations

The induction of a neural-specific gene, SCG10, by nerve growth factor in PC12 cells is transcriptional, protein synthesis dependent, and glucocorticoid inhibitable

1988 • 148 citations

Growth Cone Motility and Guidance

1988 • 134 citations

Coordinate regulation of stromelysin and collagenase genes determined with cDNA probes.

1987 • 129 citations

Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene

1987 • 127 citations

Acidic fibroblast growth factor atimulates adrenal chromaffin cells to proliferate and to extend neurites, but is not a long term survival factor

1988 • 109 citations

Further purification of epidermal growth factor by high-performance liquid chromatography

1982 • 103 citations

Nerve growth factor regulates gene expression by several distinct mechanisms.

1989 • 86 citations

Two adjacent promoter elements mediate nerve growth factor activation of the c-fos gene and bind distinct nuclear complexes.

1988 • 79 citations

Nerve growth factor activates Thy-1 and neurofilament gene transcription in rat PC12 cells

1986 • 76 citations

The dynamics of nerve growth factor-induced neurofilament and vimentin filament expression and organization in PC12 cells

1984 • 65 citations

Neurite Penetration into Collagen Gels Requires Ca<sup>2+</sup>-Dependent Metalloproteinase Activity

1989 • 61 citations

On the role of proteases, their inhibitors and the extracellular matrix in promoting neurite outgrowth.

1985 • 54 citations

Transcriptional modulation of transin gene expression by epidermal growth factor and transforming growth factor beta.

1988 • 49 citations

What happens when growth cones meet neurites: attraction or repulsion?

1987 • 17 citations