Nerve growth factor regulates gene expression by several distinct mechanisms.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

DNA cloning : a practical approach

1985 • 2,302 citations

Physiology of nerve growth factor.

1980 • 1,602 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection.

1986 • 1,063 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

A cyclic AMP- and phorbol ester-inducible DNA element

1986 • 780 citations

PC12 Pheochromocytoma Cultures in Neurobiological Research

1982 • 728 citations

Characterization and isolation of proteolytically modified nerve growth factor

1976 • 677 citations

FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA

1982 • 668 citations

Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene

1988 • 661 citations

Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors.

1985 • 506 citations

The nerve growth factor: its mode of action on sensory and sympathetic nerve cells.

1966 • 456 citations

Nerve growth factor-induced increase in electrical excitability and acetylcholine sensitivity of a rat pheochromocytoma cell line

1977 • 395 citations

Induction of the proto-oncogene fos by nerve growth factor.

1985 • 359 citations

Cloning of Complementary DNA for GAP-43, a Neuronal Growth-Related Protein

1987 • 351 citations

K-252a: a specific inhibitor of the action of nerve growth factor on PC 12 cells

1988 • 320 citations

Inducible binding of a factor to the c-fos enhancer

1986 • 310 citations

Nerve growth factor mediates phosphorylation of specific proteins

1980 • 305 citations

Molecular Cloning of a Gene Sequence Regulated by Nerve Growth Factor

1985 • 279 citations

Alterations in the surface properties of cells responsive to nerve growth factor

1978 • 279 citations

Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells.

1987 • 267 citations

Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells.

1981 • 239 citations

Mutation of the c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and the nuclear regulatory factor binding in vitro.

1987 • 238 citations

Evidence for RNA synthesis-dependent and -independent pathways in stimulation of neurite outgrowth by nerve growth factor

1978 • 224 citations

Endothelial cell mitogens derived from retina and hypothalamus: biochemical and biological similarities.

1984 • 224 citations

Protein kinase C as a component of a nerve growth factor-sensitive phosphorylation system in PC12 cells.

1986 • 197 citations

Spectrophotometric quantitation of silver grains eluted from autoradiograms

1983 • 195 citations

Identification of c-fos sequences involved in induction by insulin and phorbol esters.

1988 • 184 citations

Nerve growth factor action is mediated by cyclic AMP- and Ca+2/phospholipid-dependent protein kinases.

1986 • 169 citations

The role of cAMP in nerve growth factor-promoted neurite outgrowth in PC12 cells.

1986 • 161 citations

Transcriptional and post-transcriptional effects of nerve growth factor on expression of the three neurofilament subunits in PC-12 cells.

1988 • 153 citations

Nerve growth factor induces the genes for two proteins related to a family of calcium-binding proteins in PC12 cells.

1988 • 148 citations

The induction of a neural-specific gene, SCG10, by nerve growth factor in PC12 cells is transcriptional, protein synthesis dependent, and glucocorticoid inhibitable

1988 • 148 citations

Neurite outgrowth induced by an endothelial cell mitogen isolated from retina.

1986 • 131 citations

Calcium-Dependent Nerve Growth Factor-Stimulated Hydrolysis of Phosphoinositides in PC12 Cells

1987 • 127 citations

Clonal variants of PC12 pheochromocytoma cells with defects in cAMP-dependent protein kinases induce ornithine decarboxylase in response to nerve growth factor but not to adenosine agonists.

1985 • 113 citations

Alterations of Lipid Metabolism in Response to Nerve Growth Factor

1982 • 97 citations

Metabolic aspects of the effect of nerve growth factor on sympathetic and sensory ganglia: Protein and ribonucleic acid synthesis

1965 • 88 citations

The neurite-promoting effect of fibroblast growth factor on PC12 cells

1983 • 88 citations

Nerve growth factor-induced reduction in epidermal growth factor responsiveness and epidermal growth factor receptors in PC12 cells: An aspect of cell differentiation

1979 • 84 citations

Identification and Characterization of mRnas Regulated by Nerve Growth Factor in PC12 Cells

1987 • 67 citations

Nerve growth factor-induced neuronal differentiation of PC12 pheochromocytoma cells: Lack of inhibition by a tumor promoter

1982 • 53 citations

Adenosine inhibits cell division and promotes neurite extension in PC12 cells

1984 • 51 citations

Selective inhibition of responses to nerve growth factor and of microtubule-associated protein phosphorylation by activators of adenylate cyclase.

1986 • 51 citations

The relationship between neurite extension and phospholipid metabolism in PC12 cells.

1984 • 44 citations

Cholera Toxin and Dibutyryl Cyclic AMP Inhibit the Expression of Neurofilament Protein Induced by Nerve Growth Factor in Cultures of Naive and Primed PC12 Cells

1987 • 37 citations

The role of the tryptophan residues in the activity of the nerve growth factor

1970 • 22 citations

Increased phosphorylation of a specific nuclear protein in rat superior cervical ganglia in response to nerve growth factor

1978 • 21 citations

Isolation of NILE Glycoprotein-Related cDNA Probes

1987 • 14 citations