Role of Potassium Channels in Regulation of Cerebral Vascular Tone
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Abstract
References (173)
Physiological roles and properties of potassium channels in arterial smooth muscle
1995 • 2,146 citations
Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle
1994 • 1,704 citations
Relaxation of Arterial Smooth Muscle by Calcium Sparks
1995 • 1,383 citations
Identification of Epoxyeicosatrienoic Acids as Endothelium-Derived Hyperpolarizing Factors
1996 • 1,226 citations
Hyperpolarizing Vasodilators Activate ATP-sensitive K + Channels in Arterial Smooth Muscle
1989 • 1,197 citations
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1996 • 539 citations
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Endothelium-dependent hyperpolarization: a role in the control of vascular tone
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Pressure-dependent membrane depolarization in cat middle cerebral artery.
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Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP‐sensitive potassium channels.
1995 • 356 citations
ATP-sensitive K+channels in pancreatic, cardiac, and vascular smooth muscle cells
1998 • 349 citations
Importance of endothelium-derived hyperpolarizing factor in human arteries.
1997 • 331 citations
Extracellular K(+)‐induced hyperpolarizations and dilatations of rat coronary and cerebral arteries involve inward rectifier K(+) channels.
1996 • 320 citations
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1996 • 295 citations
Perivascular Potassium and pH as Determinants of Local Pial Arterial Diameter in Cats
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Kv2.1/Kv9.3, a novel ATP-dependent delayed-rectifier K+ channel in oxygen-sensitive pulmonary artery myocytes
1997 • 284 citations
High affinity inhibition of Ca(2+)-dependent K+ channels by cytochrome P-450 inhibitors.
1992 • 280 citations
Ryanodine receptors regulate arterial diameter and wall [Ca2+] in cerebral arteries of rat via Ca2+‐dependent K+ channels
1998 • 273 citations
Inward rectifier K+ currents in smooth muscle cells from rat resistance-sized cerebral arteries
1993 • 256 citations
Hypoxia inhibits gene expression of voltage-gated K+ channel alpha subunits in pulmonary artery smooth muscle cells.
1997 • 253 citations
Oxygen radicals mediate the cerebral arteriolar dilation from arachidonate and bradykinin in cats.
1984 • 215 citations
Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery
1997 • 214 citations
Frequency modulation of Ca2+sparks is involved in regulation of arterial diameter by cyclic nucleotides
1998 • 212 citations
Endothelium-derived hyperpolarizing factor(s): updating the unknown
1997 • 208 citations
Lung epithelial Na channel subunits are differentially regulated during development and by steroids
1995 • 199 citations
Inhibition of 20-HETE Production Contributes to the Vascular Responses to Nitric Oxide
1997 • 198 citations
Molecular Characterization of an Arachidonic Acid Epoxygenase in Rat Brain Astrocytes
1996 • 193 citations
Chloride channel blockers inhibit myogenic tone in rat cerebral arteries
1997 • 190 citations
Display of the characteristics of endothelium‐derived hyperpolarizing factor by a cytochrome P450‐derived arachidonic acid metabolite in the coronary microcirculation
1994 • 189 citations
Role of Potassium Channels in Cerebral Blood Vessels
1995 • 187 citations
20-Hydroxyeicosatetraenoic Acid-induced Vasoconstriction and Inhibition of Potassium Current in Cerebral Vascular Smooth Muscle Is Dependent on Activation of Protein Kinase C
1997 • 182 citations
Acute nociception mediated by hindpaw P2X receptor activation in the rat
1997 • 180 citations
Mechanisms of Bradykinin-Induced Cerebral Vasodilatation in Rats
1997 • 178 citations
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1988 • 174 citations
A transferable, beta‐naphthoflavone‐inducible, hyperpolarizing factor is synthesized by native and cultured porcine coronary endothelial cells.
1996 • 174 citations
Endothelium‐derived factors and hyperpolarization of the carotid artery of the guinea‐pig
1996 • 174 citations
Possible role of P-450 metabolite of arachidonic acid in vasodilator mechanism of angiotensin II type 2 receptor in the isolated microperfused rabbit afferent arteriole.
1997 • 172 citations
IL-1 stimulates intestinal myofibroblast COX gene expression and augments activation of Cl- secretion in T84 cells
1996 • 170 citations
Effects of the BKCa channel activator, NS1619, on rat cerebral artery smooth muscle
1996 • 168 citations
Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels
1996 • 159 citations
Soluble guanylate cyclase: the forgotten sibling
1997 • 154 citations
Cloning, expression, and distribution of a Ca(2+)-activated K+ channel beta-subunit from human brain.
1996 • 152 citations
Flow-mediated dilatation of the basilar artery in vivo.
1991 • 150 citations
Increased Expression of Ca 2+ -Sensitive K + Channels in the Cerebral Microcirculation of Genetically Hypertensive Rats
1998 • 144 citations
Reduced production of cGMP underlies the loss of endothelium-dependent relaxations in the canine basilar artery after subarachnoid hemorrhage.
1992 • 137 citations
Characterization of the potassium channels involved in EDHF‐mediated relaxation in cerebral arteries
1997 • 132 citations
Increased Myogenic Tone and Diminished Responsiveness to ATP-Sensitive K + Channel Openers in Cerebral Arteries From Diabetic Rats
1997 • 128 citations
Endocannabinoids: a new class of vasoactive substances
1998 • 128 citations
ENDOTHELIUM‐DERIVED HYPERPOLARIZING FACTOR
1996 • 124 citations
ATP-sensitive K+ channels mediate dilatation of cerebral arterioles during hypoxia.
1994 • 122 citations
Possible cellular mechanism for cerebral vasospasm after experimental subarachnoid hemorrhage in the dog.
1987 • 122 citations
Cerebral vasodilation during hypercapnia. Role of glibenclamide-sensitive potassium channels and nitric oxide.
1994 • 122 citations
Activators of protein kinase C decrease Ca2+spark frequency in smooth muscle cells from cerebral arteries
1997 • 120 citations
Hydroxyl radical mediates the endothelium-dependent relaxation produced by bradykinin in mouse cerebral arterioles.
1987 • 110 citations
Inhibitors of the cytochrome P450‐mono‐oxygenase and endothelium‐dependent hyperpolarizations in the guinea‐pig isolated carotid artery
1996 • 109 citations
Role of Ca 2+ -Dependent K + Channels in Cerebral Vasodilatation Induced by Increases in Cyclic GMP and Cyclic AMP in the Rat
1996 • 108 citations
Effects of a Novel Inhibitor of Guanylyl Cyclase on Dilator Responses of Mouse Cerebral Arterioles
1997 • 107 citations
Hypoxia increases the activity of Ca2+-sensitive K+ channels in cat cerebral arterial muscle cell membranes
1994 • 106 citations
Evidence Against the Involvement of Cytochrome P450 Metabolites in Endothelium‐Dependent Hyperpolarization of the Rat Main Mesenteric Artery
1997 • 102 citations
Mechanisms of Adrenomedullin-Induced Dilatation of Cerebral Arterioles
1997 • 96 citations
Epoxyeicosatrienoic acids, potassium channel blockers and endothelium‐dependent hyperpolarization in the guinea‐pig carotid artery
1998 • 95 citations
Endothelium-Dependent Dilation of Feline Cerebral Arteries: Role of Membrane Potential and Cyclic Nucleotides
1989 • 90 citations
Cannabinoid CB1 receptor and endothelium‐dependent hyperpolarization in guinea‐pig carotid, rat mesenteric and porcine coronary arteries
1998 • 87 citations
Endothelium-dependent responses of cerebral blood vessels during chronic hypertension.
1991 • 87 citations
Studies on the effects of anandamide in rat hepatic artery
1997 • 82 citations
NO/PGI2‐independent vasorelaxation and the cytochrome P450 pathway in rabbit carotid artery
1997 • 82 citations
ATP-sensitive potassium channels in the basilar artery during chronic hypertension.
1993 • 82 citations
Global Ischemia Impairs ATP-Sensitive K + Channel Function in Cerebral Arterioles in Piglets
1996 • 82 citations
Cholinergic modulation of apical Na+ channels in turtle colon: analysis of CDPC-induced fluctuations
1990 • 82 citations
Differential effects of acetylcholine, nitric oxide and levcromakalim on smooth muscle membrane potential and tone in the rabbit basilar artery
1993 • 81 citations
Endothelium‐dependent relaxation to acetylcholine in the rabbit basilar artery: importance of membrane hyperpolarization
1992 • 81 citations
Calcitonin gene-related peptide and vasodilator nerves in large cerebral arteries of cats.
1989 • 78 citations
Dilatation of Cerebral Arterioles in Response to Activation of Adenylate Cyclase Is Dependent on Activation of Ca 2+ -Dependent K + Channels
1995 • 77 citations
Role of Potassium Channels in Relaxations of Isolated Canine Basilar Arteries to Acidosis
1997 • 76 citations
Effect of carbon monoxide on rabbit cerebral arteries.
1994 • 75 citations
β-Adrenoceptor stimulation activates large-conductance Ca2+-activated K+ channels in smooth muscle cells from basilar artery of guinea pig
1995 • 74 citations
Roles of calcium‐activated and voltage‐gated delayed rectifier potassium channels in endothelium‐dependent vasorelaxation of the rabbit middle cerebral artery
1998 • 74 citations
Pressure releases a transferable endothelial contractile factor in cat cerebral arteries.
1989 • 72 citations
The dual mode of inhibition of calmodulin-dependent nitric-oxide synthase by antifungal imidazole agents
1993 • 71 citations
Altered Function of Inward Rectifier Potassium Channels in Cerebrovascular Smooth Muscle After Ischemia/Reperfusion
1998 • 70 citations
Hyperpolarization and relaxation of resistance arteries in response to adenosine diphosphate. Distribution and mechanism of action.
1991 • 63 citations
ATP-sensitive K+ channels in the kidney
1996 • 63 citations
Substance P‐induced relaxation and hyperpolarization in human cerebral arteries
1995 • 63 citations
Comparison of electrical properties of middle cerebral and mesenteric artery in cat
1980 • 62 citations
Selective inhibition by barbiturates of the synthesis of endothelium‐derived hyperpolarizing factor in the rabbit carotid artery
1995 • 61 citations
Brain Injury Impairs ATP-Sensitive K + Channel Function in Piglet Cerebral Arteries
1997 • 61 citations
Mechanisms of Action of Endothelin on Isolated Feline Cerebral Arteries: In vitro Pharmacology and Electrophysiology
1989 • 59 citations
Barium inhibits the endothelium-dependent component of flow but not acetylcholine-induced relaxation in isolated rabbit cerebral arteries.
1995 • 58 citations
Factors inducing endothelium‐dependent relaxation in the guinea‐pig basilar artery as estimated from the actions of haemoglobin
1989 • 58 citations
Modulation of Endothelium-Dependent Hyperpolarization and Relaxation to Acetylcholine in Rat Mesenteric Artery by Cytochrome P450 Enzyme Activity
1996 • 58 citations
Control of Vascular Tone by Endogenous Endothelin-1 in Human Pial Arteries
1998 • 57 citations
Effect of diabetes mellitus on response of the basilar artery to activation of ATP-sensitive potassium channels
1994 • 57 citations
Relaxation of Subarachnoid HemorrhageInduced Spasm of Rabbit Basilar Artery by the K + Channel Activator Cromakalim
1996 • 56 citations
Inhibition of cytochrome P-450 reduces voltage-gated K+ currents in pulmonary arterial myocytes
1995 • 56 citations
Role of Nitric Oxide, Cyclic Nucleotides, and the Activation of ATP-Sensitive K+ Channels in the Contribution of Adenosine to Hypoxia-Induced Pial Artery Dilation
1997 • 56 citations
Two Metabotropic γ-Aminobutyric Acid Receptors Differentially Modulate Calcium Currents in Retinal Ganglion Cells
1997 • 56 citations
Activation of Cerebellar Climbing Fibers Increases Cerebellar Blood Flow
1998 • 56 citations
Effects of neuropeptide Y on contraction, relaxation, and membrane potential of rabbit cerebral arteries.
1989 • 55 citations
Effects of extravascular acidification and extravascular alkalinization on constriction and depolarization in rat cerebral arterioles in vitro
1994 • 54 citations
Endothelium-dependent modulation of endothelin-induced vasoconstriction and membrane depolarization in cat cerebral arteries.
1990 • 54 citations
Role of Potassium Channels in Relaxations of Canine Middle Cerebral Arteries Induced by Nitric Oxide Donors
1997 • 54 citations
Cellular mechanism of force development in cat middle cerebral artery by reducedPCO2
1985 • 53 citations
Activation of Protease-Activated Receptor-2 (PAR-2) Elicits Nitric Oxide–Dependent Dilatation of the Basilar Artery In Vivo
1998 • 53 citations
Mechanisms of impaired endothelium-dependent cerebral vasodilatation in response to bradykinin in hypertensive rats.
1991 • 53 citations
Effects of clozapine on rat striatal muscarinic receptors coupled to inhibition of adenylyl cyclase activity and on the human cloned m4 receptor
1997 • 50 citations
The Nitric Oxide–Cyclic GMP Signaling System
1996 • 50 citations
The role of membrane depolarization in the contractile response of the rabbit basilar artery to 5‐hydroxytryptamine.
1987 • 48 citations
The effect of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) and charybdotoxin (CTX) on relaxations of isolated cerebral arteries to nitric oxide
1998 • 48 citations
Ionic mechanisms in spontaneous vasomotion of the rat basilar artery in vivo.
1990 • 47 citations
Prevention of Cerebral Vasospasm by Calcitonin Gene-related Peptide Slow-release Tablet after Subarachnoid Hemorrhage in Monkeys
1996 • 47 citations
Role of impaired cAMP and calcium-sensitive K+ channel function in altered cerebral hemodynamics following brain injury
1997 • 45 citations
Calcium Sparks in Vascular Smooth Muscle—Relaxation Regulators
1995 • 44 citations
MEMBRANE PROPERTIES AND EXCITATORY NEUROMUSCULAR TRANSMISSION IN THE SMOOTH MUSCLE OF DOG CEREBRAL ARTERIES
1982 • 43 citations
Hemolysate-induced contraction in smooth muscle cells of the guinea pig basilar artery.
1984 • 42 citations
The resistance of some rat cerebral arteries to the vasorelaxant effect of cromakalim and other K+ channel openers
1992 • 41 citations
The Antifungal Imidazole Clotrimazole and its Major In Vivo Metabolite are Potent Blockers of the Calcium-Activated Potassium Channel in Murine Erythroleukemia Cells
1997 • 41 citations
Role of Ca 2+ -Activated K + Channels in the Regulation of Membrane Potential and Tone of Smooth Muscle in Human Pial Arteries
1996 • 41 citations
Actions of the novel thromboxane A2 antagonists, ONO-1270 and ONO-3708, on smooth muscle cells of the guinea-pig basilar artery
1986 • 40 citations
Differential electrophysiological actions of endothelin-1 on Cl- and K+ currents in myocytes isolated from aorta, basilar and pulmonary artery.
1998 • 40 citations
Nitric oxide of neuronal origin mediates NMDA-induced cerebral hyperemia in rats
1998 • 39 citations
Nicardipine actions on smooth muscle cells and neuromuscular transmission in the guinea-pig basilar artery.
1983 • 38 citations
Effects of Ischemia on Cerebral Arteriolar Dilation to Arterial Hypoxia in Piglets
1998 • 37 citations
Role of activation of calcium-sensitive K+ channels and cAMP in opioid-induced pial artery dilation
1997 • 37 citations
Membrane electrical mechanism of basilar artery constriction and pial artery dilation by norepinephrine.
1981 • 37 citations
Influence of Cytochrome P-450 Inhibitors on Endothelium-Dependent Nitro-L-Arginine-Resistant Relaxation and Cromakalim-Induced Relaxation in Rat Mesenteric Arteries
1997 • 37 citations
A Metabolic Sensor in Action: News From the ATP-Sensitive K+-Channel
1997 • 35 citations
Effect of calcitonin gene-related peptide on delayed cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits
1996 • 35 citations
Ischemia Reduces CGRP-Induced Cerebral Vascular Dilation in Piglets
1996 • 34 citations
Distribution and Physiological Roles of ATP-Sensitive K + Channels in the Vertebrobasilar System of the Rabbit
1996 • 33 citations
Inhalation Anesthetics Inhibit the Release of Endothelium-derived Hyperpolarizing Factor in the Rabbit Carotid Artery
1995 • 31 citations
Development of calcitonin gene-related peptide slow-release tablet implanted in CSF space for prevention of cerebral vasospasm after experimental subarachnoid haemorrhage
1996 • 30 citations
Role of endothelium in regulation of smooth muscle membrane potential and tone in the rabbit middle cerebral artery
1997 • 29 citations
Lack of a causal relationship between the vasodilator effect of papaverine and cyclic AMP production in the dog basilar artery
1984 • 29 citations
Effect of several vasoactive agents on guanylate cyclase activity in isolated rat brain microvessels
1989 • 29 citations
Effect of subarachnoid hemorrhage on calcitonin gene-related peptide-induced relaxation in rabbit basilar artery.
1989 • 28 citations
The effect of tolbutamide on cerebral blood flow during hypoxia and hypercapnia in the anaesthetized rat
1993 • 28 citations
Effect of Subarachnoid Hemorrhage on Cerebral Vasodilatation in Response to Activation of ATP-Sensitive K + Channels in Chronically Hypertensive Rats
1997 • 27 citations
Sympathetic neural control of vascular muscle in reduced renal mass hypertension.
1991 • 27 citations
Effects of Maturation on Cyclic GMP-Dependent Vasodilation in Ovine Basilar and Carotid Arteries
1994 • 27 citations
Cellular mechanisms of opiate receptor stimulation in cat middle cerebral artery
1984 • 26 citations
Relaxation of the Carotid Artery to Hypoxia Is Impaired in Watanabe Heritable Hyperlipidemic Rabbits
1995 • 26 citations
Electromechanical coupling in feline basilar artery in response to serotonin
1983 • 25 citations
A method for direct patch-clamp recording from smooth muscle cells embedded in functional brain microvessels
1998 • 24 citations
Calcium-Activated K+ Channels in Cerebral Arterioles in Piglets are Resistant to Ischemia
1997 • 23 citations
Steady-State Kinetics of Ramipril in Renal Failure
1989 • 23 citations
Neuropeptide Y and vasoactive intestinal polypeptide in cerebral arteries of the rat: relationships between innervation pattern and mechanical response
1988 • 22 citations
Subarachnoid Hemorrhage and the Role of Potassium Channels in Relaxations of Canine Basilar Artery to Nitrovasodilators
1998 • 22 citations
Ways and means for left shifts in the MaxiK channel
1997 • 22 citations
Internally applied endotoxin and the activation of BK channels in cerebral artery smooth muscle via a nitric oxide‐like pathway
1998 • 20 citations
Charybdotoxin block of Ca2+-activated K+ channels in colonic muscle depends on membrane potential dynamics
1998 • 20 citations
Neuropeptide Y in cerebrovascular function: comparison of membrane potential changes and vasomotor responses evoked by NPY and other vasoconstrictors in the guinea pig basilar artery
1990 • 20 citations
Ca2+ channel antagonists and inhibition of protein kinase C each block contraction but not depolarization to 5-hydroxytryptamine in the rabbit basilar artery
1993 • 19 citations
Dilating effect of perivascularly applied potassium channel openers cromakalim and pinacidil in rat and cat pial arteries in situ
1994 • 14 citations
Effects of Potassium Channel Openers in Isolated Human Cerebral Arteries
1995 • 14 citations
Role of potassium channels in the nitrergic nerve stimulation‐induced vasodilatation in the guinea‐pig isolated basilar artery
1998 • 14 citations
Influence of the endothelium and alpha‐adrenoreceptor antagonists on responses to noradrenaline in the rabbit basilar artery.
1989 • 14 citations
Electromechanical Coupling in Rat Basilar Artery in Response to Morphine
1983 • 14 citations
Smooth muscle hyperpolarization and relaxation to acetylcholine in the rabbit basilar artery
1994 • 13 citations
Inhibition by protein kinase C of the 86Rb+ efflux and vasorelaxation induced by P1075, a KATP channel opener, in rat isolated aorta
1997 • 11 citations
Membrane activation of smooth muscle from rabbit basilar artery by dopamine
1981 • 9 citations
Electrical and Mechanical Changes during Anoxic Contractions of the Isolated Canine Basilar Artery
1993 • 6 citations
Levcromakalim decreases cytoplasmic Ca2+ and vascular tone in canine basilar artery of SAH model
1998 • 1 citations