Calcium-sensitive cytosolic phospholipase A2 (cPLA2) is expressed in human brain astrocytes

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Neuronal activity triggers calcium waves in hippocampal astrocyte networks

1992 • 818 citations

Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells.

1982 • 754 citations

LONG TERM CULTURE OF NORMAL AND NEOPLASTIC HUMAN GLIA

1968 • 706 citations

Structure and Properties of a Human Non-pancreatic Phospholipase A2

1989 • 668 citations

Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action

1992 • 614 citations

Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus

1989 • 612 citations

NMDA receptors activate the arachidonic acid cascade system in striatal neurons

1988 • 600 citations

Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, and Other Derivatives of Carbon‐20 Unsaturated Fatty Acids

1982 • 580 citations

Cloning and Recombinant Expression of Phospholipase A2 Present in Rheumatoid Arthritic Synovial Fluid

1989 • 542 citations

Receptor-mediated activation of phospholipase A2 via GTP-binding proteins: arachidonic acid and its metabolites as second messengers

1988 • 512 citations

Astroglia in CNS injury

1991 • 496 citations

New roles for glia

1991 • 464 citations

Molecular cloning and expression of human Ca(2+)-sensitive cytosolic phospholipase A2

1991 • 447 citations

Functional receptors for neurotransmitters on astroglial cells

1987 • 436 citations

Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937.

1990 • 428 citations

The Ca2(+)-sensitive cytosolic phospholipase A2 is a 100-kDa protein in human monoblast U937 cells.

1991 • 413 citations

Brain Cortical Fatty Acids and Phospholipids During and Following Complete and Severe Incomplete Ischemia

1982 • 387 citations

Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells

1989 • 375 citations

Arachidonic Acid and Other Fatty Acids Directly Activate Potassium Channels in Smooth Muscle Cells

1989 • 353 citations

Potassium Channels in Cardiac Cells Activated by Arachidonic Acid and Phospholipids

1989 • 329 citations

Synthesis and release of neuroactive substances by glial cells

1992 • 327 citations

Astrocyte heterogeneity

1990 • 254 citations

Inflammatory factors stimulate expression of group II phospholipase A2 in rat cultured astrocytes. Two distinct pathways of the gene expression

1991 • 253 citations

Phospholipid Degradation and Cellular Edema Induced by Free Radicals in Brain Cortical Slices

1982 • 221 citations

Serotonin stimulates phospholipase A2 and the release of arachidonic acid in hippocampal neurons by a type 2 serotonin receptor that is independent of inositolphospholipid hydrolysis.

1990 • 215 citations

Chapter 30: Astrocytic response to injury

1992 • 191 citations

Activation of Ethanolamine Phospholipase A₂ in Brain During Ischemia

1982 • 183 citations

Receptors for neurotransmitters on astrocytes in the mammalian central nervous system

1993 • 181 citations

Arachidonic acid metabolites as mediators of somatostatin-induced increase of neuronal M-current

1990 • 170 citations

Characterization of phospholipase A2 (PLA2) activity in gerbil brain: enhanced activities of cytosolic, mitochondrial, and microsomal forms after ischemia and reperfusion

1991 • 151 citations

Glial cell receptors

1988 • 133 citations

Influence of Severe Hypoglycemia on Brain Extracellular Calcium and Potassium Activities, Energy, and Phospholipid Metabolism

1984 • 126 citations

Astrocytes as eicosanoid‐producing cells

1988 • 122 citations

The Influence of Bicuculline‐Induced Seizures on Free Fatty Acid Concentrations in Cerebral Cortex, Hippocampus, and Cerebellum

1982 • 121 citations

Substance P‐Induced Release of Prostaglandins from Astrocytes: Regional Specialisation and Correlation with Phosphoinositol Metabolism

1991 • 104 citations

Substance P and astrocytes: stimulation of the cyclooxygenase pathway of arachidonic acid metabolism

1988 • 98 citations

Postischemic production of eicosanoids in gerbil brain.

1987 • 80 citations

Macroglia: neural cells responsive to lymphokines and growth factors

1987 • 80 citations

Effect of Bicuculline‐Induced Status Epilepticus on Prostaglandins and Hydroxyeicosatetraenoic Acids in Rat Brain Subcellular Fractions

1987 • 80 citations

Modulatory effects of prostaglandin D2, E2 and F2α on the postsynaptic actions of inhibitory and excitatory amino acids in cerebellar purkinje cell dendrites in vitro

1985 • 76 citations

Phospholipid degradation and edema development in cold-injured rat brain

1983 • 75 citations

Release of arachidonic acid by NMDA-receptor activation in the rat hippocampus

1991 • 73 citations

Behavioral and neurochemical aspects of prostaglandins in brain function

1985 • 62 citations

A transfected m5 muscarinic acetylcholine receptor stimulates phospholipase A2 by inducing both calcium influx and activation of protein kinase C.

1990 • 58 citations

Myocardial phospholipases A2 and their membrane substrates

1992 • 50 citations

P2-purinoceptor induced prostaglandin synthesis in primary rat astrocyte cultures

1988 • 48 citations

α1‐Adrenergic Receptor Mediates Arachidonic Acid Release in Spinal Cord Neurons Independent of Inositol Phospholipid Turnover

1990 • 48 citations

Hydrolysis of Endogenous Phospholipids by Rat Brain Microsomes

1985 • 45 citations

The presence of thromboxane A2 receptors in cultured astrocytes from rabbit brain

1992 • 41 citations

Endothelin‐evoked Release of Arachidonic Acid from Mouse Astrocytes in Primary Culture

1992 • 36 citations

Cytosolic PLA2: mRNA levels and potential for transcriptional regulation.

1993 • 36 citations

THE ROLE OF ASTROCYTES IN THE INTERACTION BETWEEN THE IMMUNE AND NERVOUS SYSTEM

1986 • 35 citations

Type‐1 and type‐2 astrocytes are distinct targets for prostaglandins D₂, E₂, and F_2α

1992 • 32 citations

Structure, function and regulation of mammalian phospholipases A2.

1993 • 32 citations

Degradation of membrane phospholipids in the cultured human astroglial cell line UC-11MG during ATP depletion

1993 • 27 citations

Glucocorticoid regulation of eicosanoid production by glial cells under basal and stimulated conditions

1992 • 24 citations

Astrocytes in neurotransmission. A review.

1990 • 23 citations

Continuous human glioma-derived cell lines UC-11MG and UC-302MG

1986 • 21 citations

Involvement of Extracellular Calcium and Arachidonate in [<sup>3</sup>H] Dopamine Release from Rat Tuberoinfundibular Neurons

1989 • 21 citations

Modulation of receptor-mediated signal transduction by diacylglycerol mimetics in astrocytes

1988 • 19 citations

Cerebral Phosphoinositide and Energy Metabolism During and After Insulin‐Induced Hypoglycemia

1987 • 18 citations

Ca(2+)-sensitive cytosolic phospholipase A2 (cPLA2) in human platelets.

1993 • 10 citations

Transformations of the Polyunsaturated Fatty Acids in the Brain

1977 • 8 citations

Phospholipase A₂ Activity in Cultured Glial Cells Correlation with Appearance of Myelin Markers and Effects of Steroid Hormones

1988 • 4 citations