The trophic requirements of mature motoneurons

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Cell Death During Development of the Nervous System

1991 • 3,033 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

1991 • 1,507 citations

Radiochemical micro assays for the determination of choline acetyltransferase and acetylcholinesterase activities

1969 • 1,043 citations

Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB

1991 • 847 citations

A BDNF autocrine loop in adult sensory neurons prevents cell death

1995 • 743 citations

Severe sensory and sympathetic deficits in mice lacking neurotrophin-3

1994 • 635 citations

In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons

1995 • 593 citations

Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines

1990 • 591 citations

Disruption of the CNTF gene results in motor neuron degeneration

1993 • 566 citations

Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy

1992 • 559 citations

Arrest of Motor Neuron Disease in wobbler Mice Cotreated with CNTF and BDNF

1994 • 389 citations

Sensory but not motor neuron deficits in mice lacking NT4 and BDNF

1995 • 381 citations

Apoptosis and necrosis. Basic types and mechanisms of cell death.

1993 • 353 citations

Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor.

1995 • 337 citations

Trans-synaptic regulation of growth and development of adrenergic neurones in a mouse sympathetic ganglion

1971 • 296 citations

Ventral root avulsion: An experimental model of death of adult motor neurons

1994 • 293 citations

Neurotrophic Survival Molecules for Motoneurons: An Embarrassment of Riches

1996 • 271 citations

Myogenic differentiation in permanent clonal mouse myoblast cell lines: Regulation by macromolecular growth factors in the culture medium

1981 • 259 citations

Transforming growth factor-beta. A very potent inhibitor of myoblast differentiation, identical to the differentiation inhibitor secreted by Buffalo rat liver cells.

1986 • 247 citations

Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse

1994 • 242 citations

Brain-derived neurotrophic factor promotes survival and blocks nitric oxide synthase expression in adult rat spinal motoneurons after ventral root avulsion

1995 • 175 citations

Induction of motor neuron sprouting in vivo by ciliary neurotrophic factor and basic fibroblast growth factor

1992 • 163 citations

Increased Expression of BDNF and trkB mRNA in Rat Facial Motoneurons after Axotomy

1996 • 157 citations

The biological responses of axotomized adult motoneurons to brain- derived neurotrophic factor

1994 • 148 citations

Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons.

1994 • 120 citations

Role of muscle insulin-like growth factors in nerve sprouting: suppression of terminal sprouting in paralyzed muscle by IGF-binding protein 4.

1994 • 116 citations

IGF‐II is more active than IGF‐I in stimulating L6A1 myogenesis: Greater mitogenic actions of IGF‐I delay differentiation

1994 • 100 citations

Protection of transforming growth factor β activity by heparin and fucoidan

1994 • 100 citations

The effect of elevated potassium on the time course of neuron survival in cultures of dissociated dorsal root ganglia

1977 • 68 citations

Increased trkB mRNA expression by axotomized motoneurones

1994 • 67 citations

Actions of CNTF and neurotrophins on degenerating motoneurons: Preclinical studies and clinical implications

1994 • 67 citations

Development of Rat Spinal Cord

1979 • 66 citations

Skeletal muscle-derived trophic factors prevent motoneurons from entering an active cell death program in vitro

1994 • 56 citations

Motor neuron growth factors

1996 • 51 citations

Neurite growth from, and neuronal survival within, cultured explants of the nervous system: A critical review of morphometric and stereological methods, and suggestions for the future

1991 • 44 citations

Transforming growth factor-beta-2 (TGF-β2) is associated with mature rat neuromuscular junctions

1994 • 34 citations

Involvement of polyamines in epidermal growth factor (EGF), transforming growth factor (TGF)-α and -β1 action on culture of L6 and fetal bovine myoblasts

1994 • 20 citations

Neurotrophic factors in development and plasticity of spinal neurons

1993 • 19 citations