Modulation of Aβ peptides by estrogen in mouse models

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

1996 • 4,118 citations

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1995 • 2,456 citations

Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease

1996 • 1,640 citations

Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1

1996 • 1,439 citations

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1998 • 1,336 citations

Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins

1997 • 1,015 citations

Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model

2000 • 984 citations

Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides

1998 • 545 citations

Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats

1985 • 526 citations

Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein.

1994 • 365 citations

Estradiol and progesterone regulate neuronal structure and synaptic connectivity in adult as well as developing brain

1994 • 297 citations

The Profile of Soluble Amyloid β Protein in Cultured Cell Media

1996 • 293 citations

Augmented Senile Plaque Load in Aged Female β-Amyloid Precursor Protein-Transgenic Mice

2001 • 260 citations

Ovariectomy and 17β-estradiol modulate the levels of Alzheimer’s amyloid β peptides in brain

2000 • 221 citations

Turnover of Amyloid β-Protein in Mouse Brain and Acute Reduction of Its Level by Phorbol Ester

1998 • 213 citations

Reorganization of Cholinergic Terminals in the Cerebral Cortex and Hippocampus in Transgenic Mice Carrying Mutated Presenilin-1 and Amyloid Precursor Protein Transgenes

1999 • 196 citations

Amyloid Phenotype Characterization of Transgenic Mice Overexpressing both Mutant Amyloid Precursor Protein and Mutant Presenilin 1 Transgenes

1999 • 188 citations

Estrogen Enhances Uptake of Amyloid β‐Protein by Microglia Derived from the Human Cortex

2000 • 153 citations

Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice

1999 • 104 citations

Estrogens Influence Growth, Maturation, and Amyloid β-Peptide Production in Neuroblastoma Cells and in a β-APP Transfected Kidney 293 Cell Line

1997 • 60 citations

Effective Oral Administration of 17β-Estradiol to Female C57BL/6J Mice through the Drinking Water1

1986 • 53 citations