Protein zero (P0)–deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies

Peripheral Neuropathy

1993 • 626 citations

Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons

1992 • 493 citations

Mice deficient for the glycoprotein show subtle abnormalities in myelin

1994 • 370 citations

Charcot–Marie–Tooth neuropathy type 1B is associated with mutations of the myelin P0 gene

1993 • 361 citations

Hypermyelination and demyelinating peripheral neuropathy in Pmp22-deficient mice

1995 • 360 citations

Crucial Role for the Myelin‐associated Glycoprotein in the Maintenance of Axon‐Myelin Integrity

1995 • 226 citations

Tenascin promotes cerebellar granule cell migration and neurite outgrowth by different domains in the fibronectin type III repeats.

1992 • 211 citations

De novo mutation of the myelin Po gene in Dejerine–Sottas disease (hereditary motor and sensory neuropathy type III)

1993 • 202 citations

Deletion of the serine 34 codon from the major peripheral myelin protein P0 gene in Charcot–Marie–Tooth disease type 1B

1993 • 186 citations

Enhanced expression of the extracellular matrix molecule J1/tenascin in the regenerating adult mouse sciatic nerve

1990 • 162 citations

Many naturally occurring mutations of myelin proteolipid protein impair its intracellular transport

1994 • 159 citations

THE ROLE OF MACROPHAGES AND EICOSANOIDS IN THE PATHOGENESIS OF EXPERIMENTAL ALLERGIC NEURITIS

1988 • 152 citations

Mice doubly deficient in the genes for P0 and myelin basic protein show that both proteins contribute to the formation of the major dense line in peripheral nerve myelin

1995 • 150 citations

THE HYPERTROPHIC FORMS OF HEREDITARY MOTOR AND SENSORY NEUROPATHY

1987 • 123 citations

Progress in the molecular understanding of hereditary peripheral neuropathies reveals new insights into the biology of the peripheral nervous system

1993 • 122 citations

Morphometric Analysis of Normal, Mutant, and Transgenic CNS: Correlation of Myelin Basic Protein Expression to Myelinogenesis

1992 • 111 citations

Neurological mouse mutants and the genes of myelin

1994 • 97 citations

Mutation of the myelin Po gene in Charcot — Marie — Tooth neuropathy type 1B

1993 • 92 citations

Myelin protein zero gene mutated in Charcot-Marie-tooth type 1B patients.

1993 • 84 citations

Mutation of the Myelin Po Gene in Charcot-Marie-Tooth Neuropathy Type 1

1993 • 80 citations

Expression of myelin protein gene transcripts by schwann cells of regenerating nerve

1990 • 65 citations

Identification of a de novo insertional mutation in P_o in a patient with a Déjérine - Sottas syndrome (DSS) phenotype

1994 • 48 citations

New mutation of the myelin P0 gene in a pedigree of Charcot-Marie-Tooth neuropathy 1.

1993 • 44 citations

Tenascin-C expression during Wallerian degeneration in C57BL/Wlds mice: possible implications for axonal regeneration

1995 • 40 citations

Linkage and mutation analysis in an extended family with Charcot-Marie-Tooth disease type 1B.

1994 • 32 citations

Mutations in demyelinating peripheral neuropathies support molecular model of myelin PO‐glycoprotein extracellular domain

1994 • 25 citations

Imaging myelinated nerve fibres by confocal fluorescence microscopy: individual fibres in whole nerve trunks traced through multiple consecutive internodes

1994 • 24 citations

Two cases of congenital hypomyelination neuropathy

1984 • 18 citations

Age‐Related Changes of Myelin Proteins in the Rat Peripheral Nervous System

1986 • 16 citations