Inhibition of protein breakdown in cultured cells is a consistent response to growth factors

Epidermal Growth Factor

1979 • 2,964 citations

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

1963 • 2,742 citations

Isolation of a Mouse Submaxillary Gland Protein Accelerating Incisor Eruption and Eyelid Opening in the New-born Animal

1962 • 2,192 citations

Purification of a fibroblast growth factor from bovine pituitary.

1975 • 595 citations

Growth Factors in Mammalian Cell Culture

1976 • 483 citations

“Pleiotypic Response”

1971 • 415 citations

Characterization of a New Human Diploid Cell Strain, IMR-90

1977 • 371 citations

Inhibition by Insulin of Valine Turnover in Liver

1970 • 338 citations

Polypeptides with nonsuppressible insulin-like and cell-growth promoting activities in human serum: isolation, chemical characterization, and some biological properties of forms I and II.

1976 • 319 citations

Isolation and characterization of cells from rat adipose tissue developing into adipocytes.

1978 • 252 citations

Nonsuppressible insulin-like activity (NSILA) from human serum: Recent accomplishments and their physiologic implications

1978 • 246 citations

Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells

1976 • 234 citations

Action of growth factors in the cell cycle

1979 • 125 citations

Reduced rates of proteolysis in transformed cells

1977 • 96 citations

Effect of medium composition on protein degradation and DNA synthesis in rat embryo fibroblasts.

1977 • 65 citations

Lysosomal sequestration of intracellular protein as a regulatory step in hepatic proteolysis.

1977 • 53 citations

Hormonal Regulation of Protein Degradation in Hepatoma Cells in Tissue Culture

1974 • 40 citations