Investigation of some properties of oligodeoxynucleotides containing 4'- thio-2'-deoxynucleotides: duplex hybridization and nuclease sensitivity

Evaluation of 2‘-modified oligonucleotides containing 2‘-deoxy gaps as antisense inhibitors of gene expression

1993 • 734 citations

Physicochemical properties of phospborothioate oligodeoxynucleotides

1988 • 567 citations

Therapeutic Applications of Oligonucleotides

1992 • 438 citations

Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

1993 • 410 citations

Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity

1995 • 344 citations

Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides.

1992 • 257 citations

Oligodeoxynucleotides as Antisense Inhibitors of Gene Expression

1992 • 234 citations

Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

1993 • 201 citations

Synthesis and biological activity of 2'-deoxy-4'-thio pyrimidine nucleosides

1991 • 170 citations

Therapeutic Applications Of Oligonucleotides

1992 • 158 citations

The synthesis and antiviral activity of some 4'-thio-2'-deoxy nucleoside analogs

1991 • 143 citations

Recent advances in the chemistry of anti-infective agents

1993 • 127 citations

Carbohydrate Modifications in Antisense Research

1994 • 120 citations

Comparative evaluation of seven oligonucleotide analogs as potential antisense agents

1993 • 114 citations

Mitochondrial Benzodiazepine Receptors and the Regulation of Steroid Biosynthesis

1992 • 114 citations

Progress toward oligonucleotide therapeutics: pharmacodynamic properties

1993 • 114 citations

Gene regulation : biology of antisense RNA and DNA

1992 • 106 citations

Synthesis and Anti-Herpes Virus Activity of 2‘-Deoxy-4‘-thiopyrimidine Nucleosides

1996 • 89 citations

Solvent effects on the dynamics of (dG‐dC)₃

1983 • 89 citations

Oligonucleotides as therapeutic agents

1991 • 81 citations

Synthesis and Antiviral Activity of 2‘-Deoxy-4‘-thio Purine Nucleosides

1996 • 69 citations

4′-Thio-oligo-β-D-ribonucleotides: synthesis of β-4′-thio-oligouridylates, nuclease resistance, base pairing properties, and interaction with HIV-1 reverse transcriptase

1993 • 50 citations

Sugar modified oligonucleotides I. Carbo-oligodeoxynucleotides as potential antisense agents

1989 • 46 citations

Synthesis and properties of oligodeoxynucleotides containing the analogue 2′-deoxy-4′-thiothemidine

1993 • 40 citations

Biochemical properties of oligo[(+)]-carbocyclic-thymidylates] and their complexes

1990 • 30 citations

Synthesis of decadeoxyribonucleotides containing 5-modified uracils and their interactions with restriction endonucleasesBglII,Sau3AI andMboI (Nucleosides and Nudeotides 82¹)

1988 • 25 citations

The Crystal Structure Analysis of d(CGCGAASSCGCG)2, a Synthetic DNA Dodecamer Duplex Containing Four 4'-Thio-2'-Deoxythymidine Nucleotides

1996 • 24 citations

Sugar modified oligonucleotides: Synthesis, nuclease resistance and base pairing of oligodeoxynucleotides containing 1-(4′-thio-β-d-ribofuranosyl)-thymine

1992 • 18 citations